Team:BGU Israel/Basic Part

OriginALS

OriginALS

Basic Parts

These basic parts compose the OriginALS two-dimensional ALS therapy.
We can not wait to see what other projects these parts will be part of!

For more information click on the part link:

Short description

NickName

Part link

Tissue inhibitor of metalloproteinases-1 promoter (pTIMP1)

pTIMP1

BBa_K2538005

gRNA#1 for SaCas9 targeting of IKKβ  under U6 promoter

U6 g1

BBa_K2538000

gRNA#2 for SaCas9 targeting of IKKβ  under U6 promoter

U6-g2

BBa_K2538001

gRNA#5 for SaCas9 targeting of IKKβ  under U6 promoter

U6-g5

BBa_K2538002

gRNA#6 for SaCas9 targeting of IKKβ  under U6 promoter

U6-g6

BBa_K2538003

Microglia specific promoter pF4/80

pF4/80

BBa_K2538006

Six Transmembrane Epithelial Antigen of Prostate 4 promoter (pSTEAP4) with a point mutation

pSTEAP4 +mut

BBa_K2538007

Six Transmembrane Epithelial Antigen of Prostate 4 promoter (pSTEAP4)

pSTEAP4

BBa_K2538008

Synthetic minimal adenovirus major late promoter (pMLPm)

pMLP

BBa_K2538009

Ribozyme flanked gRNA for SadCas9 VP64 targeting synthetic activation promoter pMLPm

RGR gRNA

BBa_K2538010

OriginALS

About Us


The BGU-iGEM team “OriginALS” hopes to develop an innovative therapeutic approach to prolong the life expectancy of ALS patients, using Synthetic Biology. We are dedicated to promoting ALS awareness and research in Israel through public engagement and educational activities.