Team:BUCT-China

Welcome to our team——BUCT-China!

Research and Construction of Multi-Type Fatty Acids and Glyoxylic Acid Oscillators

Background

The GntR family is a class of genes with potential transcriptional regulatory functions located in the genome of a cell. Many members of the GntR family have been shown to play an important role in the survival of various strains such as Escherichia coli, Vibrio cholerae, and Mycobacterium tuberculosis under various stressful conditions.

Description

The purpose of this experimental study was to study the key sequences, mechanism of action, and site of action of some transcriptional regulators in the GntR/FadR family. Based on this research, a new transcriptional regulatory factor was designed as a new biological component. And together with other components to construct a biological module or gene loop, through the dynamic regulation of the metabolic processes in the microbial cells, improve the yield and quality of the target product production.

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