Americans generally do not consume enough Omega-‐‑3 fatty acids, which are abundant only in fatty fish and certain seeds. Alpha linoleic acid (ALA) is essential to humans (required diet for life) and is converted within human cells, albeit inefficiently, into eicosapentanoic acid (EPA) and docosahexanoic acid (DHA). These unsaturated fatty acids cannot be included in multivitamin pills, as they quickly oxidize (become rancid) at room temperature. Few use them as cooking oils due to the taste. I propose instead to create a Bacillus subtilis strain that imports linoleic acid (LA), the principle component of corn oil, and converts it into ALA, EPA and DHA within the chicken gut (Figure 1). Americans collectively consume 9 billion broiler chickens and 80 billion eggs each year; serving sizes are more than sufficient to mask the flavor of fish oil. Most chickens, both egg layers and broilers, live on feed composed mostly of corn and soy bean meal. Corn oil is mostly linoleic acid (Omega-‐‑6). Bacillus subtilis is routinely fed to chickens as a probiotic, so a strain that over-‐‑expressed a fatty acid transporter, desaturases and elongases Enterprising poultry scientists have already shown that chickens fed a diet including 10% flax seeds produce meat and eggs that contain Omega-‐‑3 fatty acids. To begin, we have constructed a set of novel genetic tools for B. subtilis and Lactobacillus plantarum (another probiotic species).
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Styling your wiki
You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.
While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.
Uploading pictures and files
You must upload any pictures and files to the iGEM 2018 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name.
When you upload, set the "Destination Filename" to T--YourOfficialTeamName--NameOfFile.jpg. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)
Wiki template information
We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the Pages for awards link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!
Editing your wiki
On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world!
Use WikiTools - Edit in the black menu bar to edit this page