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Revision as of 08:59, 24 August 2018
To achieve our goal, we want to design a L. jensenii with a spermicidal effect which can allow a long term contraception for women. We are focusing on different types of spermidical molecules :
We are going to use two bacteria : Bacillus subtilis and Lactobacillus jensenii, two gram positive bacteria. We choosed B. subtilis because it's a model bacteria for the gram positive. Indeed the final goal is to modify L. jensenii.
Description
The different parts of the Vagineering project
Name
Type of molecule
Origin
Nisin
Lantipeptid
Lactococcus lactis
Lacticin 3147
Lantipeptid
Lactococcus lactis
Subtilosin A
Sactipeptid
Bacillus subtilis
Magainin II
Magainin
Xenopus laevis
LL37
Cathelicidin antimicrobial peptid
Homo sapiens
YLP20
Antibody
Homo sapiens
AS16
Antibody
Homo sapiens
The chassis