Difference between revisions of "Team:New York City/HD/"

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<div class="container">
 
    <nav class="sticky-top py-3 navbar navbar-expand-lg navbar-light mr-auto">
 
        <div class="container d-flex flex-column flex-md-row justify-content-between">
 
            <div class="navbar-brand"><a href="https://2018.igem.org/Team:New_York_City/">HD Resolution</a></div>
 
            <div class="collapse navbar-collapse" id="navbarSupportedContent">
 
                <ul class="navbar-nav mr-auto">
 
                    <li class="nav-item dropdown">
 
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                            Project
 
                        </a>
 
                        <div class="dropdown-menu" aria-labelledby="navbarPR">
 
                            <a class="dropdown-item" href="https://2018.igem.org/Team:New_York_City/HD/">What is HD?</a>
 
                            <a class="dropdown-item" href="">Coming Soon</a>
 
                        </div>
 
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                            Notebook
 
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                        <div class="dropdown-menu" aria-labelledby="navbarNB">
 
                            <a class="dropdown-item" href="">Coming Soon</a>
 
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                        <a class="nav-link dropdown-toggle py-2 d-none d-md-inline-block" href="#" id="navbarHP" role="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false">
 
                            Human Practices
 
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                            <a class="dropdown-item" href="">Coming Soon</a>
 
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                        <a class="nav-link" href="#">Team</a>
 
                    </li>
 
                </ul>
 
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    </nav>
 
</div>
 
  
<div class="container bg-light py-1 align-middle">
 
    <h2 align="center">What is Huntington's Disease?</h2>
 
</div>
 
 
<div class="container">
 
    <p clas="lead">Huntington's disease (HD) is an inherited, autosomal dominant disorder that causes the progressive degeneration
 
        of nerve cells in the basal ganglia, a part of the brain that is responsible for coordination and movement. It
 
        is caused by a trinucleotide repeat of 40 or more CAG codons in the huntingtin protein. The exact function of
 
        the huntingtin protein is unknown but it is critical in nerve cell function. Thus, there is a wide range of
 
        symptoms and signs from cognitive, movement, and psychiatric disorders such as:</p>
 
    <ul>
 
        <li>Muscle problems, such as contraction or rigidity</li>
 
        <li>Abnormal eye movements</li>
 
        <li>Difficulty processing information</li>
 
        <li>Fatigue, loss of energy</li>
 
        <li>Social withdrawal</li>
 
        <li>Mood swings and depression</li>
 
        <li>Amnesia and handicapped judgement</li>
 
        <li>Impaired speaking abilities and significant weight loss</li>
 
        <li>Involuntary movement and loss of physical coordination</li>
 
    </ul>
 
    <p>HD is adult-onset, usually affecting people in between their 30's to 50's. Symptoms typically worsen over a
 
        10 to 25 year period and greatly impact both mental and physical abilities. Eventually, they pass away due
 
        to heart failure or other complications.</p>
 
</div>
 
 
<div class="container bg-light py-1 align-middle">
 
    <h2 align="center">Who is affected by Huntington's Disease?</h2>
 
</div>
 
 
<div class="container">
 
    <p>Huntington's disease affects all people regardless of their gender or ethnicity; however, some group is more
 
        prone to the disease than others are. It occurs more frequently among people with European origin than among
 
        any other population. In the United States, around 30,000 people are diagnosed with Huntington's disease. This
 
        is only a small percentage of the US population, but it has the potential to grow quickly. 200,000 people are at
 
        risk of inheriting HD, as the child of an affected parent has a 50-50% chance of having a gene that
 
        causes the disease.</p>
 
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<div class="container bg-light py-1 align-middle">
 
    <h2 align="center">Is There a Cure?</h2>
 
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<div class="container">
 
    <p>Currently, the complications of Huntington's disease can be mitigated by medication for movement disorders and
 
        psychiatric disorders (such as antidepressants), along with psychotherapy, speech therapy, physical therapy,
 
        and occupational therapy. However, there exists no treatment to completely cure or slow the development of HD,
 
        although there has been ongoing research and experimental therapies.</p>
 
    <p>Our goal is to employ genetics to find an efficient resolution for HD, hence our name:
 
        <span class="shiny"><strong>HD Resolution</strong></span></p>
 
</div>
 
 
<div class="container">
 
    <p>Sources:</p>
 
    <ol>
 
        <li><a href="http://hdsa.org/what-is-hd/">hdsa.org</a></li>
 
    </ol>
 
</div>
 
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Latest revision as of 07:13, 31 August 2018