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− | <link rel="stylesheet" type="text/css" href="https://2018.igem.org/wiki/index.php?
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− | title=Template:NTHU_Taiwan/css&action=raw&ctype=text/css">
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− | <body>
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− | <div class="content">
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− | <div class="project-title">Our project this year</div>
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− | <div class="description">
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− | In an island state such as Taiwan or Japan, the aquaculture is an important industry. However, the Vibrio-related
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− | infection of aquatic animal has been a critical threat for a long time.The Vibrio-related infection leads to
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− | inestimable financial damage in Taiwan and Japan, thus, exerting huge impact on the global fishery market.
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− | <br><br>
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− | Traditionally, in order to solve the problem of Vibrio infection, the fisherman add antibiotics into the fishpond
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− | directly. But in this way, the abuse of antibiotics will lead to irreversible harm to the Mother Nature.
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− | <br><br>
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− | Our goal this year is to design a system which based on the model of succession. Our engineered E. coli will detect
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− | the chemicals secreted by Vibrio which is called AHL, then it triggers our engineered bacteria LUX system to produce
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− | an antimicrobial peptide called colicin which is able to kill Vibrio.
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− | <br><br>
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− | When the concentration of Vibrio decreases, the LUX system shuts down and triggers the expression of the suicide gene
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− | Gp2. Moreover, the regulation system is STAR/ anti – STAR system. Thus, it causes the death of our engineered bacteria
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− | and finally causes the increase of Vibrio concentration. In this way, our engineered bacteria coexist with the Vibrio
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− | and control the population. Therefore, we can control the Vibrio population and avoid fish and shrimp infection.
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− | </div>
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− | <div class="title">XGEM</div>
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− | <div class="description">
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− | We attempt to make an platfrom for igemers, expect us!
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− | </div>
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− | <div class="title">Keep in touch</div>
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− | <div class="description">
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− | <a href="https://www.facebook.com/NTHU.iGEM">
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− | <img class='icon' src="https://github.com/igem-tw-nthu/Wiki/blob/master/Image/fb_icon.png?raw=true">
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− | </a>
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− | <a href="https://www.instagram.com/igem_tw_nthu/">
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− | <img class='icon' src="https://github.com/igem-tw-nthu/Wiki/blob/master/Image/ig-logo-300x300.jpg?raw=true">
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− | </a>
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− | </div>
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− | </div>
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− | </body>
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− | </html>
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