|
|
(6 intermediate revisions by the same user not shown) |
Line 1: |
Line 1: |
− | {{NTHU_Taiwan/TopBar}} | + | {{NTHU_Taiwan/index}} |
− | | + | |
− | | + | |
− | <html>
| + | |
− | <head>
| + | |
− | <link rel="stylesheet" type="text/css" href="https://2018.igem.org/wiki/index.php?
| + | |
− | title=Template:NTHU_Taiwan/css&action=raw&ctype=text/css">
| + | |
− | <link rel="stylesheet" type="text/css" href="https://2018.igem.org/wiki/index.php?
| + | |
− | title=Template:NTHU_Taiwan/NoUglyDefault&action=raw&ctype=text/css">
| + | |
− | </haed>
| + | |
− | | + | |
− | <style>
| + | |
− | .index-project-title{
| + | |
− | font-size: 30px;
| + | |
− | padding: 10px 10px 0px 10px;
| + | |
− | }
| + | |
− | | + | |
− | .index-description{
| + | |
− | padding: 10px;
| + | |
− | color: gray;
| + | |
− | }
| + | |
− | | + | |
− | .index-title{
| + | |
− | padding: 10px 10px 0px 10px;
| + | |
− | font-size: 20px;
| + | |
− | }
| + | |
− | | + | |
− | .index-icon{
| + | |
− | height: 30px;
| + | |
− | width: 30px;
| + | |
− | padding: 0 5px;
| + | |
− | }
| + | |
− | | + | |
− | .index-herf{
| + | |
− | text-decoration-line: none
| + | |
− | }
| + | |
− | | + | |
− | </style>
| + | |
− | | + | |
− | <body>
| + | |
− | <div class="index-content">
| + | |
− | <div class="index-project-title">Our project this year</div>
| + | |
− | <div class="index-description">
| + | |
− | In an island state such as Taiwan or Japan, the aquaculture is an important industry. However, the Vibrio-related
| + | |
− | infection of aquatic animal has been a critical threat for a long time.The Vibrio-related infection leads to
| + | |
− | inestimable financial damage in Taiwan and Japan, thus, exerting huge impact on the global fishery market.
| + | |
− | <br><br>
| + | |
− | Traditionally, in order to solve the problem of Vibrio infection, the fisherman add antibiotics into the fishpond
| + | |
− | directly. But in this way, the abuse of antibiotics will lead to irreversible harm to the Mother Nature.
| + | |
− | <br><br>
| + | |
− | Our goal this year is to design a system which based on the model of succession. Our engineered E. coli will detect
| + | |
− | the chemicals secreted by Vibrio which is called AHL, then it triggers our engineered bacteria LUX system to produce
| + | |
− | an antimicrobial peptide called colicin which is able to kill Vibrio.
| + | |
− | <br><br>
| + | |
− | When the concentration of Vibrio decreases, the LUX system shuts down and triggers the expression of the suicide gene
| + | |
− | Gp2. Moreover, the regulation system is STAR/ anti – STAR system. Thus, it causes the death of our engineered bacteria
| + | |
− | and finally causes the increase of Vibrio concentration. In this way, our engineered bacteria coexist with the Vibrio
| + | |
− | and control the population. Therefore, we can control the Vibrio population and avoid fish and shrimp infection.
| + | |
− | </div>
| + | |
− | </div>
| + | |
− | | + | |
− | </body>
| + | |
− | | + | |
− | </html>
| + | |