Difference between revisions of "Team:NTU-Singapore/Test Page"

 
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     <meta name="keywords" content="iGEM, NTU, Singapore, ModVision">
 
     <meta name="keywords" content="iGEM, NTU, Singapore, ModVision">
 
     <meta name="description" content="">
 
     <meta name="description" content="">
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     <meta name="viewport" content="width=device-width, initial-scale=1.2, viewport-fit=cover">
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     <meta name="viewport" content="width=device-width, initial-scale=1.0">
 
      
 
      
 
<link rel="stylesheet" type="text/css" href="https://2018.igem.org/wiki/index.php?title=Team:NTU-Singapore/Test_Page/BootstrapCSS&action=raw&ctype=text/css">
 
<link rel="stylesheet" type="text/css" href="https://2018.igem.org/wiki/index.php?title=Team:NTU-Singapore/Test_Page/BootstrapCSS&action=raw&ctype=text/css">
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<script src="https://2018.igem.org/wiki/index.php?title=Team:NTU-Singapore/Test_Page/BlocsJS&action=raw&ctype=text/javascript"></script>
 
<script src="https://2018.igem.org/wiki/index.php?title=Team:NTU-Singapore/Test_Page/BlocsJS&action=raw&ctype=text/javascript"></script>
 
<script src="https://2018.igem.org/wiki/index.php?title=Team:NTU-Singapore/Test_Page/LazyJS&action=raw&ctype=text/javascript" defer></script>
 
<script src="https://2018.igem.org/wiki/index.php?title=Team:NTU-Singapore/Test_Page/LazyJS&action=raw&ctype=text/javascript" defer></script>
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     <title>Home</title>
 
     <title>Home</title>
 
      
 
      
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   #home_logo, #sideMenu { display:none; }
 
   #home_logo, #sideMenu { display:none; }
 
   #sideMenu, #top_title, .patrollink  {display:none;}
 
   #sideMenu, #top_title, .patrollink  {display:none;}
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   #content { width:100%; padding:0px;  margin-top:-7px; margin-left:0px;}
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   #content { width:100%; padding:0px;  margin-top:-20px; margin-left:0px;}
 
   body {background-color:white; }
 
   body {background-color:white; }
 
   #bodyContent h1, #bodyContent h2, #bodyContent h3, #bodyContent h4, #bodyContent h5 { margin-bottom: 0px; }  
 
   #bodyContent h1, #bodyContent h2, #bodyContent h3, #bodyContent h4, #bodyContent h5 { margin-bottom: 0px; }  
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<nav class="navbar row mini-nav">
 
<nav class="navbar row mini-nav">
 
<div class="navbar-header">
 
<div class="navbar-header">
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<a class="navbar-brand logo-margin" href="index.html"><img src="img/lazyload-ph.png" data-src="https://static.igem.org/mediawiki/2018/2/2b/T--NTU-Singapore--Logo.png" alt="logo" width="120" height="35" class="lazyload" /></a>
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<a class="navbar-brand logo-margin" href="index.html"><img src="img/lazyload-ph.png" data-src="https://static.igem.org/mediawiki/2018/2/2b/T--NTU-Singapore--Logo.png" alt="logo" width="150" height="42" class="lazyload" /></a>
 
<button id="nav-toggle" type="button" class="ui-navbar-toggle navbar-toggle menu-icon-uneven-b-list" data-toggle="collapse" data-target=".navbar-1">
 
<button id="nav-toggle" type="button" class="ui-navbar-toggle navbar-toggle menu-icon-uneven-b-list" data-toggle="collapse" data-target=".navbar-1">
 
<span class="sr-only">Toggle navigation</span><span class="icon-bar"></span><span class="icon-bar"></span><span class="icon-bar"></span>
 
<span class="sr-only">Toggle navigation</span><span class="icon-bar"></span><span class="icon-bar"></span><span class="icon-bar"></span>
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</div>
 
</div>
 
<div class="collapse navbar-collapse navbar-1 nav-special sidebar-nav">
 
<div class="collapse navbar-collapse navbar-1 nav-special sidebar-nav">
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<ul class="site-navigation nav navbar-nav pull-right nav-margin object-hidden">
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<ul class="site-navigation nav navbar-nav pull-right nav-margin object-hidden ">
 
<li>
 
<li>
 
<a href="index.html">Home</a>
 
<a href="index.html">Home</a>
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<ul class="dropdown-menu" role="menu">
 
<ul class="dropdown-menu" role="menu">
 
<li>
 
<li>
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<a href="index.html">Team Members</a>
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<a href="index.html">Our Team</a>
 
</li>
 
</li>
 
<li>
 
<li>
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<ul class="dropdown-menu" role="menu">
 
<ul class="dropdown-menu" role="menu">
 
<li>
 
<li>
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<a href="index.html">Description</a>
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<a href="index.html">DNA Editor</a>
 
</li>
 
</li>
 
<li>
 
<li>
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<a href="index.html">Design</a>
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<a href="index.html">REPAIR</a>
 
</li>
 
</li>
 
<li>
 
<li>
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<a href="index.html">Experiments</a>
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<a href="index.html">Nanopore</a>
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</li>
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<li>
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<a href="index.html">Notebook</a>
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</li>
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<li>
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<a href="interlab-measurement.html">InterLab</a>
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</li>
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<li>
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<a href="index.html">Model</a>
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</li>
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<li>
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<a href="index.html">Results</a>
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</li>
 
</li>
 
<li>
 
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</ul>
 
</ul>
 
</div>
 
</div>
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</li>
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<li>
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<a href="interlab-measurement.html">InterLab</a>
 
</li>
 
</li>
 
<li>
 
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<li>
 
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<a href="index.html">Composite Parts</a>
 
<a href="index.html">Composite Parts</a>
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</li>
 
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<li>
 
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<a href="index.html">Part Collection</a>
 
 
</li>
 
</li>
 
</ul>
 
</ul>
 
</div>
 
</div>
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</li>
 
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<a href="interlab-measurement.html">Safety</a>
 
 
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<ul class="dropdown-menu" role="menu">
 
<ul class="dropdown-menu" role="menu">
 
<li>
 
<li>
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<a href="index.html">Home</a>
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<a href="index.html">Metal Criteria</a>
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</li>
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<li>
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<a href="index.html">Best Human Practice</a>
 
</li>
 
</li>
 
</ul>
 
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</div>
 
</div>
 
<div class="container">
 
<div class="container">
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<div class="row picture-margin ">
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<div class="row picture-margin">
 
<div class="col-sm-12">
 
<div class="col-sm-12">
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<img src="img/lazyload-ph.png" data-src="https://static.igem.org/mediawiki/2018/3/3e/T--NTU-Singapore--Logo_Eye.png" class="center-block mg-sm hero-break img-responsive lazyload" width="500" srcset="img/Eye%20Structure.png 2x, img/Eye%20Structure.png 3x" /><img src="img/lazyload-ph.png" data-src="https://static.igem.org/mediawiki/2018/2/2b/T--NTU-Singapore--Logo.png" class="center-block mg-lg img-responsive logo-break lazyload" width="218" height="38" />
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<img src="img/lazyload-ph.png" data-src="https://static.igem.org/mediawiki/2018/3/3e/T--NTU-Singapore--Logo_Eye.png" class="center-block mg-sm hero-break img-responsive lazyload" width="500" srcset="img/Eye%20Structure.png 2x, img/Eye%20Structure.png 3x" /><img src="img/lazyload-ph.png" data-src="https://static.igem.org/mediawiki/2018/2/2b/T--NTU-Singapore--Logo.png" class="center-block mg-lg img-responsive logo-break lazyload" width="218" height="38" />
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<h1 class="text-center mg-lg hero-bloc-text tc-white ">
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<h1 class="text-center hero-bloc-text mg-md tc-white ">
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<span style="font-size:80%;">A CRISPR/Cas Base-Editing Toolkit </span>
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A CRISPR/Cas Base-Editing Toolkit
 
</h1>
 
</h1>
 
<h3 class="text-center mg-lg hero-bloc-text-sub tc-white ">
 
<h3 class="text-center mg-lg hero-bloc-text-sub tc-white ">
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<div class="col-sm-6 col-sm-pull-6">
 
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<h2 class="mg-lg tc-black  text-left">
 
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<span style="font-size:80%;">A Continuation and Beyond.</span>
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A Continuation and Beyond.
 
</h2>
 
</h2>
 
<h3 class=" mg-md text-left">
 
<h3 class=" mg-md text-left">
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<span style="font-size:80%;">CRISPR/Cas9 DNA Base Editor</span>
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CRISPR/Cas9 DNA Base Editor
 
</h3>
 
</h3>
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<p class=" mg-lg text-left">
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<p class=" mg-lg text-justify">
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<div style="text-align: left;"><div style="line-height: 200%;">With the successful truncated dCas9-mediated transcriptional activation last year, we moved further this year into DNA base editing using CRISPR/Cas9 system. We also improved our truncated dCas9 further with novel strategies for higher binding efficiency.</div></div>
+
With the successful truncated dCas9-mediated transcriptional activation last year, we moved further this year into DNA base editing using CRISPR/Cas9 system. We also improved our truncated dCas9 further with novel strategies for higher binding efficiency.
 
</p><a href="index.html" class="btn btn-wire btn-rd pull-left btn-lg">Project Improve</a>
 
</p><a href="index.html" class="btn btn-wire btn-rd pull-left btn-lg">Project Improve</a>
 
</div>
 
</div>
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<div class="col-sm-6">
 
<div class="col-sm-6">
 
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<h2 class="ipad-bloc-text-vc tc-black  mg-lg">
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<span style="font-size:80%;">Human-Centred Research</span>
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Human-Centred Research
 
</h2>
 
</h2>
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<p class="mg-lg  text-left">
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<p class="mg-lg  text-justify">
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<div style="text-align: left;"><div style="line-height: 200%;">Our research involves not only the students and scientists, but also the Singapore public. While doing our project, we looked into the public opinions towards gene editing. Our human practice tells how&nbsp;our project evolved around the local community that we live in.&nbsp;</div></div>
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Our research involves not only the students and scientists, but also the Singapore public. While doing our project, we looked into the public opinions towards gene editing. Our human practice tells how&nbsp;our project evolved around the local community that we live in.&nbsp;
 
</p><a href="index.html" class="btn btn-wire btn-rd">Integrated Human Practice</a>
 
</p><a href="index.html" class="btn btn-wire btn-rd">Integrated Human Practice</a>
 
</div>
 
</div>
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<div class="col-sm-6 col-sm-pull-6">
 
<div class="col-sm-6 col-sm-pull-6">
 
<h2 class="mg-lg  tc-black text-left">
 
<h2 class="mg-lg  tc-black text-left">
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<span style="font-size:80%;">Adapt to Change.</span>
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Adapt to Change.
 
</h2>
 
</h2>
 
<h3 class="text-left  mg-md">
 
<h3 class="text-left  mg-md">
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<span style="font-size:80%;">CRISPR/Cas13b RNA Base Editor</span>
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CRISPR/Cas13b RNA Base Editor
 
</h3>
 
</h3>
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<p class="mg-lg  text-left">
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<p class="mg-lg  text-justify">
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<div style="text-align: left;"><div style="line-height: 200%;">As we have learnt through our interviews with medical doctors and interaction with the public, it is evident that RNA editing is more promising and better accep-ted in our society. Hence, we reflected on our project and ventured into RNA editing.</div></div>
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As we have learnt through our interviews with medical doctors and interaction with the public, it is evident that RNA editing is more promising and better accep-ted in our society. Hence, we reflected on our project and ventured into RNA editing.
 
</p><a href="index.html" class="btn btn-wire btn-rd pull-left">Project REPAIR</a>
 
</p><a href="index.html" class="btn btn-wire btn-rd pull-left">Project REPAIR</a>
 
</div>
 
</div>
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<div class="col-sm-6">
 
<div class="col-sm-6">
 
<h2 class="mg-lg  tc-black">
 
<h2 class="mg-lg  tc-black">
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<span style="font-size:80%;">Aim Even Higher.</span>
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Aim Even Higher.
 
</h2>
 
</h2>
 
<h3 class=" mg-md">
 
<h3 class=" mg-md">
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<span style="font-size:80%;">Modification-Sensitive&nbsp;Nanopore Sequencing</span>
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Modification-Sensitive&nbsp;Nanopore Sequencing
 
</h3>
 
</h3>
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<p class="mg-lg ">
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<p class="mg-lg text-justify">
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<div style="text-align: left;"><div style="line-height: 200%;">To address the significant concern around the safety of RNA editing technology, we designed an unbiased, accurate RNA sequencing tool. Expanding the nanopore sequencing platform, we hope to enhance the saftey of RNA editing.</div></div>
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To address the significant concern around the safety of RNA editing technology, we designed an unbiased, accurate RNA sequencing tool. Expanding the nanopore sequencing platform, we hope to enhance the saftey of RNA editing.
 
</p><a href="index.html" class="btn btn-wire btn-rd pull-left">Project Nanopore</a>
 
</p><a href="index.html" class="btn btn-wire btn-rd pull-left">Project Nanopore</a>
 
</div>
 
</div>
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</div>
 
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Latest revision as of 17:37, 23 September 2018

Home

A Continuation and Beyond.

CRISPR/Cas9 DNA Base Editor

With the successful truncated dCas9-mediated transcriptional activation last year, we moved further this year into DNA base editing using CRISPR/Cas9 system. We also improved our truncated dCas9 further with novel strategies for higher binding efficiency.

Project Improve

Human-Centred Research

Our research involves not only the students and scientists, but also the Singapore public. While doing our project, we looked into the public opinions towards gene editing. Our human practice tells how our project evolved around the local community that we live in. 

Integrated Human Practice

Adapt to Change.

CRISPR/Cas13b RNA Base Editor

As we have learnt through our interviews with medical doctors and interaction with the public, it is evident that RNA editing is more promising and better accep-ted in our society. Hence, we reflected on our project and ventured into RNA editing.

Project REPAIR

Aim Even Higher.

Modification-Sensitive Nanopore Sequencing

To address the significant concern around the safety of RNA editing technology, we designed an unbiased, accurate RNA sequencing tool. Expanding the nanopore sequencing platform, we hope to enhance the saftey of RNA editing.

Project Nanopore