Difference between revisions of "Team:NTU-Singapore"

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<img src="img/lazyload-ph.png" data-src="https://static.igem.org/mediawiki/2018/3/3e/T--NTU-Singapore--Logo_Eye.png" class="center-block mg-sm hero-break img-responsive lazyload" width="500" srcset="img/Eye%20Structure.png 2x, img/Eye%20Structure.png 3x" style="padding-top: 3%;"/><img src="img/lazyload-ph.png" data-src="https://static.igem.org/mediawiki/2018/2/2b/T--NTU-Singapore--Logo.png" class="center-block mg-lg img-responsive logo-break lazyload" width="218" height="38" />
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<img src="img/lazyload-ph.png" data-src="https://static.igem.org/mediawiki/2018/3/3e/T--NTU-Singapore--Logo_Eye.png" class="center-block mg-sm hero-break img-responsive lazyload" width="500" srcset="img/Eye%20Structure.png 2x, img/Eye%20Structure.png 3x" /><img src="img/lazyload-ph.png" data-src="https://static.igem.org/mediawiki/2018/2/2b/T--NTU-Singapore--Logo.png" class="center-block mg-lg img-responsive logo-break lazyload" width="218" height="38" />
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<span style="font-size:80%;">A CRISPR/Cas Base-Editing Toolkit </span>
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A CRISPR/Cas Base-Editing Toolkit
 
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<span style="font-size:80%;">A Continuation and Beyond.</span>
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A Continuation and Beyond.
 
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<span style="font-size:80%;">CRISPR/Cas9 DNA Base Editor</span>
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CRISPR/Cas9 DNA Base Editor
 
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<div style="text-align: left;"><div style="line-height: 200%;">With the successful truncated dCas9-mediated transcriptional activation last year, we moved further this year into DNA base editing using CRISPR/Cas9 system. We also improved our truncated dCas9 further with novel strategies for higher binding efficiency.</div></div>
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With the successful truncated dCas9-mediated transcriptional activation last year, we moved further this year into DNA base editing using CRISPR/Cas9 system. We also improved our truncated dCas9 further with novel strategies for higher binding efficiency.
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</p><a href="index.html" class="btn btn-wire btn-rd pull-left btn-lg" style="margin-top: 5%;">Project Improve</a>
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</p><a href="index.html" class="btn btn-wire btn-rd pull-left btn-lg">Project Improve</a>
 
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<span style="font-size:80%;">Human-Centred Research</span>
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Human-Centred Research
 
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<div style="text-align: left;"><div style="line-height: 200%;">Our research involves not only the students and scientists, but also the Singapore public. While doing our project, we looked into the public opinions towards gene editing. Our human practice tells how&nbsp;our project evolved around the local community that we live in.&nbsp;</div></div>
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Our research involves not only the students and scientists, but also the Singapore public. While doing our project, we looked into the public opinions towards gene editing. Our human practice tells how&nbsp;our project evolved around the local community that we live in.&nbsp;
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</p><a href="index.html" class="btn btn-wire btn-rd" style="margin-top: 5%;">Integrated Human Practice</a>
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</p><a href="index.html" class="btn btn-wire btn-rd">Integrated Human Practice</a>
 
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<span style="font-size:80%;">Adapt to Change.</span>
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Adapt to Change.
 
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<span style="font-size:80%;">CRISPR/Cas13b RNA Base Editor</span>
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CRISPR/Cas13b RNA Base Editor
 
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<div style="text-align: left;"><div style="line-height: 200%;">As we have learnt through our interviews with medical doctors and interaction with the public, it is evident that RNA editing is more promising and better accep-ted in our society. Hence, we reflected on our project and ventured into RNA editing.</div></div>
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As we have learnt through our interviews with medical doctors and interaction with the public, it is evident that RNA editing is more promising and better accep-ted in our society. Hence, we reflected on our project and ventured into RNA editing.
 
</p><a href="index.html" class="btn btn-wire btn-rd pull-left">Project REPAIR</a>
 
</p><a href="index.html" class="btn btn-wire btn-rd pull-left">Project REPAIR</a>
 
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<span style="font-size:80%;">Aim Even Higher.</span>
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Aim Even Higher.
 
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<span style="font-size:80%;">Modification-Sensitive&nbsp;Nanopore Sequencing</span>
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Modification-Sensitive&nbsp;Nanopore Sequencing
 
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<div style="text-align: left;"><div style="line-height: 200%;">To address the significant concern around the safety of RNA editing technology, we designed an unbiased, accurate RNA sequencing tool. Expanding the nanopore sequencing platform, we hope to enhance the saftey of RNA editing.</div></div>
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To address the significant concern around the safety of RNA editing technology, we designed an unbiased, accurate RNA sequencing tool. Expanding the nanopore sequencing platform, we hope to enhance the saftey of RNA editing.
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</p><a href="index.html" class="btn btn-wire btn-rd pull-left" style="margin-top: 5%;">Project Nanopore</a>
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</p><a href="index.html" class="btn btn-wire btn-rd pull-left">Project Nanopore</a>
 
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Revision as of 18:12, 23 September 2018

Home

A Continuation and Beyond.

CRISPR/Cas9 DNA Base Editor

With the successful truncated dCas9-mediated transcriptional activation last year, we moved further this year into DNA base editing using CRISPR/Cas9 system. We also improved our truncated dCas9 further with novel strategies for higher binding efficiency.

Project Improve

Human-Centred Research

Our research involves not only the students and scientists, but also the Singapore public. While doing our project, we looked into the public opinions towards gene editing. Our human practice tells how our project evolved around the local community that we live in. 

Integrated Human Practice

Adapt to Change.

CRISPR/Cas13b RNA Base Editor

As we have learnt through our interviews with medical doctors and interaction with the public, it is evident that RNA editing is more promising and better accep-ted in our society. Hence, we reflected on our project and ventured into RNA editing.

Project REPAIR

Aim Even Higher.

Modification-Sensitive Nanopore Sequencing

To address the significant concern around the safety of RNA editing technology, we designed an unbiased, accurate RNA sequencing tool. Expanding the nanopore sequencing platform, we hope to enhance the saftey of RNA editing.

Project Nanopore