Difference between revisions of "Template:Virginia/index"

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     <img src="https://static.igem.org/mediawiki/2018/7/73/T--Virginia--2018_dark_1.svg" alt="logo" class="center">
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   <h3>Microbial Symphony</h3>
 
   <h3>Microbial Symphony</h3>
 
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     <h3>Constitutive Expression</h3>
 
     <h3>Constitutive Expression</h3>
 
     <!-- <img src="/images/landing_page/lp_wildtype.svg" alt="constitutive expression"></img> -->
 
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     <p>The gene of interest is hooked up to a constitutive promoter, resulting in constant expression. The primary benefit of this "system" is its inherent simplicity - expression will always just occur. However, when optimizing yields, a flaw in this system becomes evident; low yields.</p>
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     <p>This system involves hookin a gene of interest up to a constitutive promoter, resulting in constant expression. The primary benefit of this "system" is its inherent simplicity - expression will always just occur. However, when optimizing yields, a flaw in this system becomes evident; low yields.</p>
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    <button class="constitutive_button">Click to see it in action</button>
 
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     <h3>Inducible Expression</h3>
 
     <h3>Inducible Expression</h3>
 
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     <!-- <img src="/images/landing_page/lp_quorus.svg" alt="induced expression"></img> -->
     <p>A better solution resulting in higher yields involves hooking the gene in question up to an inducible promoter. This system gives the culture time to grow without gene expression; growth occurs an at an accelerated rate because all metabolic activity is focused on growth. Once the culture has reached an optimal cell density, an artificial inducer can be added, switching on production of the gene in question.</p>
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     <p>This system involves hooking the gene in question up to an inducible promoter. Growth occurs an at an accelerated rate because no metabolic activity is put towards production. Once the culture has grown to an optimal density, an artificial inducer can be added, switching production on.</p>
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    <button class="inducible_button">Click to see it in action</button>
 
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Revision as of 21:37, 4 October 2018

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Microbial Symphony

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 <section>

Constitutive Expression

This system involves hookin a gene of interest up to a constitutive promoter, resulting in constant expression. The primary benefit of this "system" is its inherent simplicity - expression will always just occur. However, when optimizing yields, a flaw in this system becomes evident; low yields.

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The Problem

In biomanufacturing, there are two common systems for inducing expression of some gene of interest.

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 <section>

Inducible Expression

This system involves hooking the gene in question up to an inducible promoter. Growth occurs an at an accelerated rate because no metabolic activity is put towards production. Once the culture has grown to an optimal density, an artificial inducer can be added, switching production on.

   <button class="inducible_button">Click to see it in action</button>
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