Difference between revisions of "Team:New York City"

(Undo revision 201609 by Amars (talk))
(Undo revision 201601 by Andy kim (talk))
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{{New_York_City}}
 
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     <link rel="stylesheet" href="https://stackpath.bootstrapcdn.com/bootstrap/4.1.3/css/bootstrap.min.css" integrity="sha384-MCw98/SFnGE8fJT3GXwEOngsV7Zt27NXFoaoApmYm81iuXoPkFOJwJ8ERdknLPMO"
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        <div class="container d-flex flex-column flex-md-row justify-content-between">
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                <div class="navbar-brand"><a href="https://2018.igem.org/Team:New_York_City">New York City iGEM</a></div>
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            <div class="navbar-brand"><a href="https://2018.igem.org/Team:New_York_City">New York City iGEM</a></div>
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                <div class="collapse navbar-collapse" id="navbarSupportedContent">
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            <div class="collapse navbar-collapse" id="navbarSupportedContent">
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                            <a class="nav-link dropdown-toggle py-2 d-none d-md-inline-block" href="#" id="navbarPR"
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                        <a class="nav-link dropdown-toggle py-2 d-none d-md-inline-block" href="#" id="navbarPR" role="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false">
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                                role="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false">
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                            Project
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                                Project
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                        </a>
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                            </a>
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                        <div class="dropdown-menu" aria-labelledby="navbarPR">
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                            <div class="dropdown-menu" aria-labelledby="navbarPR">
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                            <a class="dropdown-item" href="https://2018.igem.org/Team:New_York_City/HD">What is Huntington's?</a>
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                                <a class="dropdown-item" href="https://2018.igem.org/Team:New_York_City/HD">What is
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                            <a class="dropdown-item" href="https://2018.igem.org/Team:New_York_City/Description">Description</a>
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                                    Huntington's?</a>
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                            <a class="dropdown-item" href="https://2018.igem.org/Team:New_York_City/Design">Design</a>
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                                <a class="dropdown-item" href="https://2018.igem.org/Team:New_York_City/Description">Description</a>
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                        </div>
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                                <a class="dropdown-item" href="https://2018.igem.org/Team:New_York_City/Design">Design</a>
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                            Notebook
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                                role="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false">
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                        <div class="dropdown-menu" aria-labelledby="navbarNB">
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                                Notebook
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                            <a class="dropdown-item" href="">Coming Soon</a>
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                            </a>
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                            <div class="dropdown-menu" aria-labelledby="navbarNB">
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                                <a class="dropdown-item" href="">Coming Soon</a>
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                            </div>
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                        <a class="nav-link dropdown-toggle py-2 d-none d-md-inline-block" href="#" id="navbarHP" role="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false">
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                            Human Practices
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                        <li class="nav-item dropdown">
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                        </a>
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                            <a class="nav-link dropdown-toggle py-2 d-none d-md-inline-block" href="#" id="navbarHP"
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                        <div class="dropdown-menu" aria-labelledby="navbarHP">
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                                role="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false">
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                            <a class="dropdown-item" href="https://2018.igem.org/Team:New_York_City/Human_Practices">Human Practices</a>
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                                Human Practices
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                            <a class="dropdown-item" href="https://2018.igem.org/Team:New_York_City/Integrated_Practices">Integrated Practices</a>
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                            </a>
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                        </div>
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                            <div class="dropdown-menu" aria-labelledby="navbarHP">
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                    </li>
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                                <a class="dropdown-item" href="https://2018.igem.org/Team:New_York_City/Human_Practices">Human
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                                    Practices</a>
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                                <a class="dropdown-item" href="https://2018.igem.org/Team:New_York_City/Integrated_Practices">Integrated
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                                    Practices</a>
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                         <li class="nav-item">
 
                         <li class="nav-item">
 
                             <a class="nav-link py-2 d-none d-md-inline-block" href="https://2018.igem.org/Team:New_York_City/Team"
 
                             <a class="nav-link py-2 d-none d-md-inline-block" href="https://2018.igem.org/Team:New_York_City/Team"
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                             </a>
 
                             </a>
 
                         </li>
 
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    <div align="center">
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        <h1>Meet the Team!</h1>
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    </div>
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    <div class="row teamRow text-center">
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                    <img class="card-img-top head" src="https://static.igem.org/mediawiki/2018/4/41/T--New_York_City--Julia_Lee.JPG">
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                    <h5 class="card-title">Julia Lee</h5>
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                    <p class="card-text">Hey, everyone! I am one of the Project Leads for our team, as well as a member
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                        of Wet Lab, Outreach/Fundraising, and Art. I'm a senior at Stuyvesant High School, and I enjoy
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                        watching cute dog videos, writing, and playing tennis.</p>
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                </div>
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             </div>
 
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        <div class="col-sm-6">
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</div>
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                <div class="card-body">
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                    <img class="card-img-top head" src="https://static.igem.org/mediawiki/2018/f/f7/T--New_York_City--Selena_Park.JPG">
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                    <h5 class="card-title">Selena Park</h5>
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                    <p class="card-text">Hi guys! I'm Selena, a senior at Stuyvesant, and I'm part of Wet Lab, Art
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                        Team, Photography, and the Coordinator for our team! I plan on becoming a medical examiner in
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                        the future. I enjoy doing many things such as reading a variety of literature and watching
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                        dissection videos from Inside Nature's Giants.</p>
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    </div>
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    <div class="row teamRow text-center">
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<div class="container text-center" align="center">
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         <div class="col-sm-12" align="center">
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            <h1 class="display-4">Testing the efficacy of mRNA displacement technique in huntingtin cell lines to
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                    <img class="card-img-top head" src="https://static.igem.org/mediawiki/2018/b/b5/T--New_York_City--Rachel_Lee.JPG">
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                 treat Huntington's Disease</h1>
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                    <h5 class="card-title">Rachel Lee</h5>
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             <br/>
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                    <p class="card-text">Hello! I'm one of the Computational Liaison and Design Leads, and I'm also a
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                        part of Photography. I'm a senior at Stuyvesant High School, and I aspire to be an architect.
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                        In my free time, I love to fence, travel, and watch Netflix.</p>
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         <div class="col-sm-6">
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                <div class="card-body">
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                    <img class="card-img-top head" src="https://static.igem.org/mediawiki/2018/8/8e/T--New_York_City--Erica_Sugimura.JPG">
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                    <h5 class="card-title">Erica Sugimura</h5>
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                    <p class="card-text">Hey! My name is Erica and I am part of the Website, Social Media, and
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                        Photography Team. I am a rising sophomore at Stuyvesant High School and a part of Robotics
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                        there. In my free time, I like to skate around my neighborhood listening to music.</p>
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         </div>
 
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     </div>
 
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     <div class="row teamRow text-center">
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            <div class="card">
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             <img class="headimage" src="https://static.igem.org/mediawiki/2018/1/1c/T--New_York_City--logo.PNG" width=100%/>
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                <div class="card-body">
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                    <img class="card-img-top head" src="https://static.igem.org/mediawiki/2018/0/09/T--New_York_City--Anton_Tarazi.JPG">
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                    <h5 class="card-title">Anton Tarazi</h5>
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                    <p class="card-text">Hi! I'm Anton, a rising senior at Bronxville High School. This year I am
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                        working in iGEM as a co-lead on both the Wet Lab Team and the Computational Chemistry Team.
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                        During my free time I enjoy mountain biking and practicing card magic.</p>
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                <div class="card-body">
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                    <img class="card-img-top head" src="https://static.igem.org/mediawiki/2018/8/82/T--New_York_City--Andy_Kim.JPG">
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                    <h5 class="card-title">Andy Kim</h5>
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                    <p class="card-text">Hi! I'm Andy, a rising senior at Ridge High School. This year, I will be
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                        working with fellow iGEM students as the Website Team Lead, Outreach/Fundraising Co-Lead, and
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                        member of the Video Production Team. Back home in New Jersey, I love to play basketball, eat
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                        with friends, and 3D print.</p>
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                </div>
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            </div>
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         </div>
 
         </div>
 
     </div>
 
     </div>
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    <div class="row teamRow text-center">
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</div>
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<br/>
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<div class="container" align="center">
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                <div class="card-body">
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    <div class="row">
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                    <img class="card-img-top head" src="https://static.igem.org/mediawiki/2018/2/22/T--New_York_City--Abraham_Lee.JPG">
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        <div class="col-sm-4">
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                    <h5 class="card-title">Abraham Lee</h5>
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            <div class="container">
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                    <p class="card-text">Hello everyone! I'm Abraham, a rising senior at Stuyvesant High School. I am a
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                <h2 class="display-4">WHAT</h2>
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                        part of the outreach and the social media teams. I love watching and playing sports as well as
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                <p align="left" class="lead">Huntington's Disease (HD) is a genetic disorder that results in the breakdown of nerve cells in the
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                        meeting new people. I hope to have a successful and enjoyable time working with my peers!</p>
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                    brain. Although the disease affects the whole brain, the basal ganglia, which plays a critical role in
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                </div>
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                    motor functions and behavior, is most severely affected. Thus, symptoms of HD include involuntary
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                    movements, personality changes, and cognitive problems. Over time, the effects of HD is extremely
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                    debilitating, eventually rendering a patient unable to speak, walk, or even reason.</p>
 
             </div>
 
             </div>
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            <br>
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        <div class="col-sm-6">
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             <div class="container">
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             <div class="card">
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                 <h2 class="display-4">WHY</h2>
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                 <div class="card-body">
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                <p align="left" class="lead">HD is a result of a specific mutation in the huntingtin (HTT) gene, which results in a faulty production
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                    <img class="card-img-top head" src="https://static.igem.org/mediawiki/2018/f/f2/T--New_York_City--Jennifer_Liu.JPG">
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                    of the HTT protein, mHTT. The mutation is a trinucleotide repeat of the codon CAG, where 40 or more will
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                    <h5 class="card-title">Jennifer Liu </h5>
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                    lead to the expression of HD.</p>
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                    <p class="card-text">Hi everyone! My name is Jennifer, but I normally go by Jennie. I am a co-lead
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                        of the Video Production Team as well as a member of the Outreach & Fundraising and Photography
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                        & Documenting Teams. This coming fall, I will be a senior at Stuyvesant High School. My
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                        passions are singing, songwriting, and dancing.</p>
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             </div>
 
             </div>
 
         </div>
 
         </div>
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         <div class="col-sm-4" align="center">
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    </div>
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            <img src="https://static.igem.org/mediawiki/2018/d/d8/T--New_York_City--neuron.jpg" width=300>
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    <div class="row teamRow text-center">
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         <div class="col-sm-6">
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                <div class="card-body">
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                    <img class="card-img-top head" src="https://static.igem.org/mediawiki/2018/6/6b/T--New_York_City--Glen_Chung.JPG">
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                    <h5 class="card-title">Glen Chung</h5>
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                    <p class="card-text">Hi! My name is Glen and I'm a sophomore at Dwight school. I'm a member of the
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                        Outreach team. My passions are hockey and drum.</p>
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         </div>
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         <div class="col-sm-6">
+
         <div class="col-sm-4">
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             <div class="card">
+
             <div class="container">
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                 <div class="card-body">
+
                 <h2 class="display-4">WHO</h2>
−
                    <img class="card-img-top head" src="https://static.igem.org/mediawiki/2018/9/9d/T--New_York_City--Lucas_Lee.JPG">
+
                <p align="left" class="lead">The most common form of HD is adult-onset, affecting people between their 30s and 40s.
−
                    <h5 class="card-title">Lucas Lee</h5>
+
                    Many people form families and have children by the time they are diagnosed with HD, which automatically
−
                    <p class="card-text">I'm Lucas Lee from Korea, a rising junior at Brook Hill School in Texas. This
+
                    gives their children a 50% chance of inheriting the disease. HD affects about 1 in every 10,000
−
                        year I'm working for art design and film for iGEM. I love to play soccer with my friends and
+
                    people worldwide.</p>
−
                        watch movies. Nice to meet you guys.</p>
+
−
                </div>
+
 
             </div>
 
             </div>
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        </div>
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            <br>
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    </div>
+
             <div class="container">
−
    <div class="row teamRow text-center">
+
                 <h2 class="display-4">HOW</h2>
−
        <div class="col-sm-6">
+
                <p align="left" class="lead">Our goal is to develop a cure to Huntington's Disease by employing RNA strand displacement
−
             <div class="card">
+
                    technology to target erroneous mRNA within the affected cells and replace it with the corrected RNA
−
                 <div class="card-body">
+
                     strand for proper protein synthesis.
−
                    <img class="card-img-top head" src="https://static.igem.org/mediawiki/2018/7/75/T--New_York_City--Jaeah_Kim.JPG">
+
                </p>
−
                    <h5 class="card-title">Jaeah Kim</h5>
+
−
                    <p class="card-text">Hi! My name is Jaeah and I'm a sophomore at Hunter College High School. I am a
+
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                        member of the Wet-Lab team. My hobbies are biology, research, and stargazing.</p>
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                </div>
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        </div>
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                     <img class="card-img-top head" src="https://static.igem.org/mediawiki/2018/2/29/T--New_York_City--Jaejeong_Kim.JPG">
+
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                    <h5 class="card-title">Jaejeong Kim</h5>
+
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                    <p class="card-text">Hi! My name is Jae and I'm a rising sophomore at Hunter College High School. I
+
−
                        am a member of the Wet-Lab team. In my spare time, I like to sleep, read, and go birdwatching.</p>
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                </div>
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             </div>
 
             </div>
 
         </div>
 
         </div>
 
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</div>
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    <br />
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<div align="center">
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                <div class="card-body">
+
    <video height="320" width="auto" controls>
−
                    <img class="card-img-top head" src="https://static.igem.org/mediawiki/2018/7/7c/T--New_York_City--Eric_Ha.JPG">
+
        <source src="https://static.igem.org/mediawiki/2018/0/06/T--New_York_City--Video.mp4" type="video/mp4">
−
                    <h5 class="card-title">Eric (Yunsu) Ha</h5>
+
        </video>
−
                    <p class="card-text">Hi, everyone! I am one of the Project Leads for our team, and I am also part
+
</div>
−
                        of the Wetlab team. I am a senior at St. Francis Preparatory High School, and I like to play
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<br/>
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                        the guitar, watch movies, and play soccer during my free time.</p>
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<div class="container" align="center">
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                </div>
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    <div class="row" align="center">
−
            </div>
+
        <div class="col-sm-4">
 +
            <a href="https://hdsa.org/"><img class="sponsor" src="https://static.igem.org/mediawiki/2018/a/a4/T--New_York_City--hdsa.png"/></a>
 
         </div>
 
         </div>
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         <div class="col-sm-4">
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             <div class="card">
+
             <a href="http://www.hdfoundation.org/"><img class="sponsor" src="https://static.igem.org/mediawiki/2018/8/86/T--New_York_City--hdf.png"/></a>
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                <div class="card-body">
+
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+
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                    <h5 class="card-title">Emily</h5>
+
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                    <p class="card-text">Hi there! My name's Emily, and I'm a rising senior at Stuart Country Day
+
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                        School. I am a Project Lead, as well as a member of the Wetlab, Photography, and Video
+
−
                        Production teams. I also act as the final editor for the Website team. If you follow our iGEM
+
−
                        twitter account, you can also catch me there! In my free time, I'll either be singing, fencing,
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                        or reading a good book.</p>
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                </div>
+
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            </div>
+
 
         </div>
 
         </div>
−
    </div>
+
         <div class="col-sm-4">
−
    <div class="row teamRow text-center">
+
             <a href="https://www.cerebralpalsy.org.au/"><img class="sponsor" src="https://static.igem.org/mediawiki/2018/0/03/T--New_York_City--cpa.png"/></a>
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         <div class="col-sm-6">
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                    <h5 class="card-title">Karis</h5>
+
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                    <p class="card-text">Hi, I'm Karis, a sophomore at Jericho High School. I'm a part of the social
+
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                        media team, managing the Facebook page, and the wet lab team. I like to play the violin and
+
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                        volleyball, watch Netflix, and listen to music in my free time.</p>
+
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                </div>
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+
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        </div>
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−
        <div class="col-sm-6">
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+
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+
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                    <h5 class="card-title">Minuk</h5>
+
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                    <p class="card-text">Hi, I'm Minuk, a junior at Stuyvesant High School. I am part of Wet Lab Team,
+
−
                        the Computational Chemistry Team and the Website Team. I enjoy playing the guitar and watching
+
−
                        soccer. I am looking forward to work with awesome team members over summer!</p>
+
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                </div>
+
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            </div>
+
 
         </div>
 
         </div>
 
     </div>
 
     </div>
−
     <div class="row teamRow text-center">
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     <br/>
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</div>
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+
<div class="container" align="center">
−
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    <div class="row" align="center">
−
 
+
        <div class="col-sm-4">
−
                    <h5 class="card-title">Sangmin</h5>
+
            <a href="https://www.steptember.us/"><img class="sponsor" src="https://static.igem.org/mediawiki/2018/3/38/T--New_York_City--step.png"/></a>
−
                    <p class="card-text">Hello! I am a junior at the Horace Mann School, and I will be taking part in
+
−
                        the Website, Video Production, and Computational Chem teams. In my free time, I play basketball
+
−
                        and go out into the city to eat lots of different food with my friends.</p>
+
−
                </div>
+
−
            </div>
+
 
         </div>
 
         </div>
−
         <div class="col-sm-6">
+
         <div class="col-sm-4">
−
             <div class="card">
+
             <a href="https://nya.hdsa.org//"><img class="sponsor" src="https://static.igem.org/mediawiki/2018/6/61/T--New_York_City--ya.png"/></a>
−
                <div class="card-body">
+
−
 
+
−
                    <h5 class="card-title">Syhyoung</h5>
+
−
                    <p class="card-text">Hello, I'm Syhyoung. I am in the Outreach and Fundraising team. I am rising
+
−
                        junior at Marianapolis Prep School. I am interested in economics. I usually watch sports
+
−
                        videos, especially soccer videos, and play soccer in free time. I also like to watch action
+
−
                        movies.</p>
+
−
                </div>
+
−
            </div>
+
 
         </div>
 
         </div>
−
    </div>
+
         <div class="col-sm-4">
−
    <div class="row teamRow text-center">
+
             <a href="https://hdsa.donordrive.com/index.cfm?fuseaction=donorDrive.participant&participantID=48528"><img class="sponsor" src="https://static.igem.org/mediawiki/2018/1/11/T--New_York_City--hope.png"/></a>
−
 
+
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         <div class="col-sm-6">
+
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+
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+
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+
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                    <h5 class="card-title">Justin</h5>
+
−
                    <p class="card-text">Hi, My name is Jiho (Justin) Lee. I am a rising junior at Canterbury School in
+
−
                        Connecticut. I'm part of the outreach and fundraising team, social media team, and a co-lead in
+
−
                        website team. I like to play football and lacrosse, watch movies, and listen to music in my
+
−
                        free time.</p>
+
−
                </div>
+
−
            </div>
+
−
        </div>
+
−
        <div class="col-sm-6">
+
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+
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                <div class="card-body">
+
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+
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                    <h5 class="card-title">Suyoung</h5>
+
−
                    <p class="card-text">Hi! I'm Young. I am rising junior at Shattuck St.Mary's School in Minnesota. I
+
−
                        am in Wet Lab and Fundraising Team. I love watching movies and playing violin in free time. I
+
−
                        am really looking forward to work with great members and experience new things.</p>
+
−
                </div>
+
−
            </div>
+
 
         </div>
 
         </div>
 
     </div>
 
     </div>
−
     <div class="row teamRow text-center">
+
     <br/>
−
        <div class="col-sm-6">
+
</div>
−
            <div class="card">
+
<div class="container" align="center">
−
                <div class="card-body">
+
    <div class="row" align="center">
−
 
+
        <div class="col-sm-3">
−
                    <h5 class="card-title">Si Yeon (Sean) Cho</h5>
+
−
                    <p class="card-text">I'm a senior at Avon Old Farms, a boarding school in Connecticut. I was born
+
−
                        in Incheon then moved to Vancouver, Canada when I was 3 years old. I lived there for thirteen
+
−
                        years then moved to Connecticut for boarding school. I play soccer and hockey as well as play
+
−
                        the Alto Saxophone.</p>
+
−
                </div>
+
−
            </div>
+
 
         </div>
 
         </div>
−
 
+
         <div class="col-sm-2">
−
         <div class="col-sm-6">
+
             <a href="https://www.facebook.com/HDResolution/"><i class="fab fa-facebook-f display-4"></i></a>
−
             <div class="card">
+
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                <div class="card-body">
+
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                    <h5 class="card-title">Hedy</h5>
+
−
                    <p class="card-text">I'm Hedy, a rising junior at Stuyvesant! I enjoy exploring quaint cafes and
+
−
                        marathoning horror movies with friends, volunteering with Red Cross, and listening to tropical
+
−
                        house to relieve stress. Although this is my first year, I'm excited to participate in iGEM as
+
−
                        Wetlab lead, secretary, and member of outreach!</p>
+
−
                </div>
+
−
            </div>
+
 
         </div>
 
         </div>
−
    </div>
+
         <div class="col-sm-2">
−
 
+
             <a href="https://twitter.com/HDNYC_iGEM"><i class="fab fa-twitter display-4"></i></a>
−
    <div class="row teamRow text-center">
+
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                    <h5 class="card-title">Junsu (James) Ha</h5>
+
−
                    <p class="card-text">Hello, I'm James, a rising junior at Fulton Science Academy. This year I am
+
−
                        working in website and fundraising for IGEM. In my free time, I love to play soccer and watch
+
−
                        movies.</p>
+
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+
−
            </div>
+
 
         </div>
 
         </div>
−
         <div class="col-sm-6">
+
         <div class="col-sm-2">
−
             <div class="card">
+
             <a href="https://www.instagram.com/nyc_igem/"><i class="fab fa-instagram display-4"></i></a>
−
                <div class="card-body">
+
−
 
+
−
                    <h5 class="card-title">Hojun (Terry) Kang</h5>
+
−
                    <p class="card-text">Hi, I'm Hojun(Terry) Kang. I was born in Seoul and came to Columbia, South
+
−
                        Carolina to study in 2016. I'm a rising junior at Ben Lippen High School and I'm a part of
+
−
                        fundraising and website team. </p>
+
−
                </div>
+
−
            </div>
+
 
         </div>
 
         </div>
−
    </div>
+
         <div class="col-sm-3">
−
 
+
−
    <div class="row teamRow text-center">
+
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         <div class="col-sm-6">
+
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            <div class="card">
+
−
                <div class="card-body">
+
−
 
+
−
                    <h5 class="card-title">Eumin</h5>
+
−
                    <p class="card-text">Hi everyone, I'm one of the Project Leads for our team, and I'm also part of
+
−
                        the Wetlab, Computational Liaison, Outreach, and Website teams. I'm a senior at Horace Mann,
+
−
                        and I enjoy playing the cello and playing cards with friends during my free time.</p>
+
−
                </div>
+
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            </div>
+
−
        </div>
+
−
        <div class="col-sm-6">
+
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            <div class="card">
+
−
                <div class="card-body">
+
−
 
+
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                    <h5 class="card-title">Kaitlyn</h5>
+
−
                    <p class="card-text">Hey! I am Kaitlyn, and I am a member of the Wetlab lab team. I am a senior at
+
−
                        Bergen County Academies in New Jersey, where I captain the school's fencing team and advocate
+
−
                        with the UNICEF club. Outside of school, I enjoy competing in club fencing, traveling, and
+
−
                        photography.</p>
+
−
                </div>
+
−
            </div>
+
−
        </div>
+
−
    </div>
+
−
    <div align="center">
+
−
        <h1>Advisors</h1>
+
−
    </div>
+
−
    <div class="row teamRow text-center">
+
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        <div class="col-sm-6">
+
−
            <div class="card">
+
−
                <div class="card-body">
+
−
                    <img class="card-img-top head" src="https://static.igem.org/mediawiki/2018/6/6e/T--New_York_City--Frank.JPG">
+
−
                    <h5 class="card-title">Frank Muradov</h5>
+
−
                    <p class="card-text">Frank is our project advisor and PI, and he has a passion for management and
+
−
                        team building. With over ten years of experience in investment management, research and real
+
−
                        estate, Frank enjoys turning around companies, from start-ups to investment companies and real
+
−
                        estate properties to drive innovation, efficiency and performance. Currently studying part-time
+
−
                        in Law School and educated at Columbia University, Frank enjoys cycling and active lifestyle.</p>
+
−
                </div>
+
−
            </div>
+
−
        </div>
+
−
        <div class="col-sm-6">
+
−
            <div class="card">
+
−
                <div class="card-body">
+
−
                    <img class="card-img-top head" src="https://static.igem.org/mediawiki/2018/f/f7/T--New_York_City--Russell.JPG">
+
−
                    <h5 class="card-title">Russell Hanson</h5>
+
−
                    <p class="card-text">Russell Hanson is our PI and Advisor, and is an assistant professor of
+
−
                        Genetics at Mt. Sinai Medical School. He is interested in applying synthetic biology and
+
−
                        computational genetic techniques to neuroscience and personalized health care. He also likes
+
−
                        cats and techno music.</p>
+
−
                </div>
+
−
            </div>
+
−
        </div>
+
−
    </div>
+
−
    <div class="row teamRow text-center">
+
−
        <div class="col-sm-6">
+
−
            <div class="card">
+
−
                <div class="card-body">
+
−
                    <img class="card-img-top head" src="https://static.igem.org/mediawiki/2018/6/6e/T--New_York_City--Frank.JPG">
+
−
                    <h5 class="card-title">Amar Seoparson</h5>
+
−
                    <p class="card-text">Amar is our Website advisor. He is an NYU grad with extensive experience in
+
−
                        entrepreneurship.</p>
+
−
                </div>
+
−
            </div>
+
−
        </div>
+
−
        <div class="col-sm-6">
+
−
            <div class="card">
+
−
                <div class="card-body">
+
−
                    <img class="card-img-top head" src="https://static.igem.org/mediawiki/2018/4/4f/T--New_York_City--Jamie.JPG">
+
−
                    <h5 class="card-title">Jamie Lee</h5>
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Revision as of 02:47, 6 October 2018

Testing the efficacy of mRNA displacement technique in huntingtin cell lines to treat Huntington's Disease



WHAT

Huntington's Disease (HD) is a genetic disorder that results in the breakdown of nerve cells in the brain. Although the disease affects the whole brain, the basal ganglia, which plays a critical role in motor functions and behavior, is most severely affected. Thus, symptoms of HD include involuntary movements, personality changes, and cognitive problems. Over time, the effects of HD is extremely debilitating, eventually rendering a patient unable to speak, walk, or even reason.


WHY

HD is a result of a specific mutation in the huntingtin (HTT) gene, which results in a faulty production of the HTT protein, mHTT. The mutation is a trinucleotide repeat of the codon CAG, where 40 or more will lead to the expression of HD.

WHO

The most common form of HD is adult-onset, affecting people between their 30s and 40s. Many people form families and have children by the time they are diagnosed with HD, which automatically gives their children a 50% chance of inheriting the disease. HD affects about 1 in every 10,000 people worldwide.


HOW

Our goal is to develop a cure to Huntington's Disease by employing RNA strand displacement technology to target erroneous mRNA within the affected cells and replace it with the corrected RNA strand for proper protein synthesis.