Difference between revisions of "Team:Tec-Chihuahua/Collaborations"

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            <center><img src="https://static.igem.org/mediawiki/2017/b/b6/T--Tec-Chihuahua--ErwiFinalB.png"/></center>
  
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<center><h2>Bee a hero!</h2>
  
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<h3>★  ALERT! </h3>
 
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<p>This page is used by the judges to evaluate your team for the <a href="https://2018.igem.org/Judging/Medals">medal criterion</a> or <a href="https://2018.igem.org/Judging/Awards"> award listed below</a>. </p>
 
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<p> Delete this box in order to be evaluated for this medal criterion and/or award. See more information at <a href="https://2018.igem.org/Judging/Pages_for_Awards"> Instructions for Pages for awards</a>.</p>
 
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<p align="justify"> American and European Foulbrood are diseases found in honey bee (Apis mellifera) beehives all around the world that affect larva in their prepupal stage. The causal agents of these are two gram-positive bacteria, Paenibacillus larvae, and Melissococcus plutonius. Nowadays, two techniques for the treatment of AFB and EFB have used: antibiotics (chloramphenicol and oxytetracycline) and incineration of affected hives. The first technique promotes the development of antibiotic resistance in the bacteria and the second one causes great monetary losses for beekeepers. The production of heterologous proteins in Escherichia coli is proposed for P. larvae and M. plutonius inhibition. An expression vector with native bee antimicrobial peptide genes (defensin 1/abaecin and defensin 2/apidaecin) will be inserted in the bacteria. Interactions between these peptides will be confirmed through a factorial experiment with a factor for each peptide. The final product, purified proteins with a specific packaging that can be released in the presence of P. larvae and M. plutonius will be available for beekeepers to apply in their beehives and inhibit the proliferation of pathogenic bacteria.  </p>
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<h1>Collaborations</h1>
 
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Sharing and collaboration are core values of iGEM. We encourage you to reach out and work with other teams on difficult problems that you can more easily solve together.
 
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<h3>Silver Medal Criterion #2</h3>
 
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Complete this page if you intend to compete for the silver medal criterion #2 on collaboration. Please see the <a href="https://2018.igem.org/Judging/Medals">2018 Medals Page</a> for more information.
 
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<h4> Which other teams can we work with? </h4>
 
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You can work with any other team in the competition, including software, hardware, high school and other tracks. You can also work with non-iGEM research groups, but they do not count towards the iGEM team collaboration silver medal criterion.
 
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In order to meet the silver medal criteria on helping another team, you must complete this page and detail the nature of your collaboration with another iGEM team.
 
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Here are some suggestions for projects you could work on with other teams:
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<li> Improve the function of another team's BioBrick Part or Device</li>
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<li> Characterize another team's part </li>
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<li> Debug a construct </li>
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<li> Model or simulate another team's system </li>
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<li> Test another team's software</li>
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<li> Help build and test another team's hardware project</li>
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<li> Mentor a high-school team</li>
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Revision as of 23:07, 11 June 2018

Erwinions

Bee a hero!

American and European Foulbrood are diseases found in honey bee (Apis mellifera) beehives all around the world that affect larva in their prepupal stage. The causal agents of these are two gram-positive bacteria, Paenibacillus larvae, and Melissococcus plutonius. Nowadays, two techniques for the treatment of AFB and EFB have used: antibiotics (chloramphenicol and oxytetracycline) and incineration of affected hives. The first technique promotes the development of antibiotic resistance in the bacteria and the second one causes great monetary losses for beekeepers. The production of heterologous proteins in Escherichia coli is proposed for P. larvae and M. plutonius inhibition. An expression vector with native bee antimicrobial peptide genes (defensin 1/abaecin and defensin 2/apidaecin) will be inserted in the bacteria. Interactions between these peptides will be confirmed through a factorial experiment with a factor for each peptide. The final product, purified proteins with a specific packaging that can be released in the presence of P. larvae and M. plutonius will be available for beekeepers to apply in their beehives and inhibit the proliferation of pathogenic bacteria.




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