Difference between revisions of "Team:NEU China A/Model"
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<span class="card-title black-text" style="font-size:2.5em">Introduction</span> | <span class="card-title black-text" style="font-size:2.5em">Introduction</span> | ||
<p class="gray-text" style="font-size:1.5em">In the affected area of patients with inflammatory bowel disease, the concentration of nitric oxide is significantly increased, so we chose it as the input signal of our anti-inflammatory device. However, the nitric oxide is very unstable, so we have introduced an amplifier which can converts unstable gas signals into stable intracellular signals for sustained high-level output. The amplifier is based on a positive feedback loop. Transcription activator B-A can self-drive in a manner independent of the input signal for a period of time after the signal is input, and the metabolic flow in this cycle can be transferred to the output circuit (Figure 1). </p> | <p class="gray-text" style="font-size:1.5em">In the affected area of patients with inflammatory bowel disease, the concentration of nitric oxide is significantly increased, so we chose it as the input signal of our anti-inflammatory device. However, the nitric oxide is very unstable, so we have introduced an amplifier which can converts unstable gas signals into stable intracellular signals for sustained high-level output. The amplifier is based on a positive feedback loop. Transcription activator B-A can self-drive in a manner independent of the input signal for a period of time after the signal is input, and the metabolic flow in this cycle can be transferred to the output circuit (Figure 1). </p> | ||
| − | <img style="width:100%;height:100%;" src="https:// | + | <img style="width:100%;height:100%;" src="https://static.igem.org/mediawiki/2018/6/6c/T--NEU_China_A--model_figure1.png"></img> |
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Revision as of 15:24, 15 October 2018
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Introduction
In the affected area of patients with inflammatory bowel disease, the concentration of nitric oxide is significantly increased, so we chose it as the input signal of our anti-inflammatory device. However, the nitric oxide is very unstable, so we have introduced an amplifier which can converts unstable gas signals into stable intracellular signals for sustained high-level output. The amplifier is based on a positive feedback loop. Transcription activator B-A can self-drive in a manner independent of the input signal for a period of time after the signal is input, and the metabolic flow in this cycle can be transferred to the output circuit (Figure 1).