Difference between revisions of "Team:DLUT China B/Human Practices"

(修改内容图片。)
(修改文案。)
Line 20: Line 20:
 
         <div id="contents"></div>
 
         <div id="contents"></div>
 
         <div id="article">
 
         <div id="article">
 +
            <div class="mainText">
 +
                <p>We carried out human practices from the perspectives of the public, doctors and researchers, and get
 +
                    different feedback to promote our projects further.</p>
 +
            </div>
 +
 
             <div>
 
             <div>
                 <h2 class="title">Brochure Designing and Preaching</h2>
+
                 <h2 class="title">Interview with the public</h2>
 
                 <div class="mainText">
 
                 <div class="mainText">
                     <p>Our team of practice designed a brochure on knowledge about kidney disease carefully in order to
+
                     <p>The team members conducted a social survey. We found that many people are too busy to go to the
                         make more patients with diabetes and hypertension recognize the dangers of the development of
+
                         hospital for regular medical examinations. People pay less attention to the health of the
                         chronic kidney disease(CKD), and help the old to prevent CKD, hypertension and diabetes early.In
+
                         kidneys. We want to change this situation by using our portable urine testing equipment.
                         July 2018, we held a knowledge preaching about the early prevention of CKD in Jianshan Community
+
                         According to the practical data, we have found that more than 80% of respondents are willing to
                         of Dalian ,and at the same time, we distributed our brochure designed by ourselves.In a summer
+
                        use our products. Considering about the binding time of antigen and antibody and the
                         house in the community, we distributed the brochure to some aunts,which lead them to understand
+
                         corresponding time of liquid crystal, the acceptable waiting time for respondents is about 40
                        the dangers of kidney disease, the causes of kidney disease, and methods for preventing early
+
                         minutes. We will shorten the waiting time under the condition of ensuring the accuracy of
                         kidney disease. Besides, we answered many questions about diabetes and high blood pressure asked
+
                         measurement in the subsequent experiments.</p>
                        by those aunts patiently. After we had a further communication with community residents by
+
                    <p>This interview and sample survey enriched our project background data. We analyzed and processed
                         interviewing them, we clearly felt that they had a deeper understanding of the dangers of CKD
+
                         the data obtained from the survey and found that our project does have certain market demand.
                         and the importance of its early prevention,which means our practice is successful enough.</p>
+
                         This also laid the foundation for our subsequent optimization of experimental conditions.</p>
 
                     <table class="img">
 
                     <table class="img">
 
                         <tr>
 
                         <tr>
                             <td><img src="https://static.igem.org/mediawiki/2018/0/0c/T--DLUT_China_B--HumanPractice6.jpg"></td>
+
                             <td><img src="https://static.igem.org/mediawiki/2018/b/b4/T--DLUT_China_B--HumanPractice14.jpg">
                             <td><img src="https://static.igem.org/mediawiki/2018/1/17/T--DLUT_China_B--HumanPractice7.jpg"></td>
+
                             </td>
 
                         </tr>
 
                         </tr>
 
                         <tr>
 
                         <tr>
                             <td><img src="https://static.igem.org/mediawiki/2018/3/38/T--DLUT_China_B--HumanPractice8.jpg"></td>
+
                             <td>
                             <td><img src="https://static.igem.org/mediawiki/2018/f/f1/T--DLUT_China_B--HumanPractice9.jpg"></td>
+
                                <p class="footnote">Fig.1 interview with the public</p>
 +
                             </td>
 
                         </tr>
 
                         </tr>
 
                     </table>
 
                     </table>
Line 48: Line 54:
  
 
             <div>
 
             <div>
                 <h2 class="title">Interviews with Doctors</h2>
+
                 <h2 class="title">Interviews with doctors</h2>
 
                 <div class="mainText">
 
                 <div class="mainText">
                     <p>During the summer vacation, the team members carried out practical activities throughout the
+
                     <p>In August 2018, the team members went to Linyi City People's Hospital of Shandong Province to
                        country and went to the hospital to interview the specialists in the kidney department. We not
+
                        interview Dr. Liu Haijun, a specialist in nephrology. We knew that early diagnosis and treatment
                         only understand the serious situation that diabetes and hypertension cause the proportion of
+
                         are extremely important in delaying the development of kidney disease. Only when the patient has
                        chronic kidney disease in China to rise year by year, but also know that patients with diabetes
+
                         obvious symptoms will he go to the hospital for an examination. But they may already have
                         have no early and staged awareness. When patients come to the hospital for treatment, most of
+
                         entered the dominant diabetic nephropathy (overtDN).</p>
                        them have obvious symptoms and enter CKD phase III, and early visits and treatments are
+
                    <p>Blood test is the most common diagnosis method of the hospital currently. It takes ¥48 to test
                         extremely important for the development of delayed kidney disease. At present, the diagnosis
+
                        the blood β2-microglobulin. However, Dr.Liu said that if a portable urine test method can be
                        method of the hospital is mainly blood test, but the doctor said that if a non-invasive portable
+
                        developed, it can not only alleviate the pain of blood drawing, but also greatly improve the
                        detection method through urine can be developed, it can not only alleviate the pain of blood
+
                        awareness of diabetes patients and the rate of early visits.</p>
                        drawing, but also have a very high rate of early detection and treatment. In this interview, we
+
                    <p>In this interview we exchanged ideas with doctors, and we have learned that from a clinical
                         learned the importance and urgent needs of early detection in the treatment of chronic kidney
+
                         perspective, our project is more suitable for use at home. It can greatly arouse the awareness
                         disease and the importance of improving the awareness of early treatment of patients, and more
+
                         of early patients, which can indirectly improve the diagnosis rate and provide the best time for
                         deeply recognized the practicality and usefulness of our projects.</p>
+
                         treatment.</p>
 
                     <table class="img">
 
                     <table class="img">
 
                         <tr>
 
                         <tr>
                             <td><img src="https://static.igem.org/mediawiki/2018/9/9c/T--DLUT_China_B--HumanPractice10.jpg"></td>
+
                             <td><img src="https://static.igem.org/mediawiki/2018/9/9c/T--DLUT_China_B--HumanPractice10.jpg">
                             <td><img src="https://static.igem.org/mediawiki/2018/d/d4/T--DLUT_China_B--HumanPractice11.jpg"></td>
+
                            </td>
 +
                             <td><img src="https://static.igem.org/mediawiki/2018/d/d4/T--DLUT_China_B--HumanPractice11.jpg">
 +
                            </td>
 +
                        </tr>
 +
                        <tr>
 +
                            <td colspan="2">
 +
                                <p class="footnote">Fig.2 Interviews with doctors</p>
 +
                            </td>
 
                         </tr>
 
                         </tr>
 
                     </table>
 
                     </table>
Line 73: Line 86:
  
 
             <div>
 
             <div>
                 <h2 class="title">Product Research, Fun Marketing</h2>
+
                 <h2 class="title">Interview with the researches in the Dalian Institute of Chemical Physics(DICP)</h2>
 
                 <div class="mainText">
 
                 <div class="mainText">
                     <p>In order to further understand the market demand for our products, the patient's recognition of
+
                     <p>In order to better understand the current situation of urine testing, the team members came to
                         products and their performance expectations for the products, we designed a questionnaire of the
+
                         the Research Group of Biomolecular Efficient Separation and Characterization of Dalian Institute
                         product. And to help people understand the superiority of our products, we have designed a
+
                        of Chemical Physics, Chinese Academy of Sciences in October 2018. We exchanged ideas with
                         product-based storyline, and we hope to attract more people who interest in our products in the
+
                         researcher Yuan Huiming. Researcher Yuan said that the main problem in urine testing is to
                         form of anthropomorphic storytelling and made our content of the project is impressive.</p>
+
                        eliminate interference from other proteins in the urine. The nanobody of β2-microglobulin we
 +
                         selected is more specific and can solve this problem well. On the other hand, our liquid crystal
 +
                         detection method has extremely high sensitivity and has great advantages for the detection of
 +
                        trace proteins in urine.</p>
 +
                    <p>This exchange allowed us to see the achievability and practical application of our project from
 +
                        the aspect of technical application. It also let us have confidence in our projects.</p>
 
                     <table class="img">
 
                     <table class="img">
 
                         <tr>
 
                         <tr>
                             <td><img src="https://static.igem.org/mediawiki/2018/c/c4/T--DLUT_China_B--HumanPractice12.jpg"></td>
+
                             <td><img src="https://static.igem.org/mediawiki/2018/c/c4/T--DLUT_China_B--HumanPractice12.jpg">
                             <td><img src="https://static.igem.org/mediawiki/2018/3/31/T--DLUT_China_B--HumanPractice13.jpg"></td>
+
                            </td>
 +
                             <td><img src="https://static.igem.org/mediawiki/2018/3/31/T--DLUT_China_B--HumanPractice13.jpg">
 +
                            </td>
 +
                        </tr>
 +
                        <tr>
 +
                            <td colspan="2">
 +
                                <p class="footnote">Fig.3 Interview with the researches</p>
 +
                            </td>
 
                         </tr>
 
                         </tr>
 
                     </table>
 
                     </table>

Revision as of 13:17, 16 October 2018

Human Practices

Human Practices

We carried out human practices from the perspectives of the public, doctors and researchers, and get different feedback to promote our projects further.

Interview with the public

The team members conducted a social survey. We found that many people are too busy to go to the hospital for regular medical examinations. People pay less attention to the health of the kidneys. We want to change this situation by using our portable urine testing equipment. According to the practical data, we have found that more than 80% of respondents are willing to use our products. Considering about the binding time of antigen and antibody and the corresponding time of liquid crystal, the acceptable waiting time for respondents is about 40 minutes. We will shorten the waiting time under the condition of ensuring the accuracy of measurement in the subsequent experiments.

This interview and sample survey enriched our project background data. We analyzed and processed the data obtained from the survey and found that our project does have certain market demand. This also laid the foundation for our subsequent optimization of experimental conditions.

Fig.1 interview with the public

Interviews with doctors

In August 2018, the team members went to Linyi City People's Hospital of Shandong Province to interview Dr. Liu Haijun, a specialist in nephrology. We knew that early diagnosis and treatment are extremely important in delaying the development of kidney disease. Only when the patient has obvious symptoms will he go to the hospital for an examination. But they may already have entered the dominant diabetic nephropathy (overtDN).

Blood test is the most common diagnosis method of the hospital currently. It takes ¥48 to test the blood β2-microglobulin. However, Dr.Liu said that if a portable urine test method can be developed, it can not only alleviate the pain of blood drawing, but also greatly improve the awareness of diabetes patients and the rate of early visits.

In this interview we exchanged ideas with doctors, and we have learned that from a clinical perspective, our project is more suitable for use at home. It can greatly arouse the awareness of early patients, which can indirectly improve the diagnosis rate and provide the best time for treatment.

Fig.2 Interviews with doctors

Interview with the researches in the Dalian Institute of Chemical Physics(DICP)

In order to better understand the current situation of urine testing, the team members came to the Research Group of Biomolecular Efficient Separation and Characterization of Dalian Institute of Chemical Physics, Chinese Academy of Sciences in October 2018. We exchanged ideas with researcher Yuan Huiming. Researcher Yuan said that the main problem in urine testing is to eliminate interference from other proteins in the urine. The nanobody of β2-microglobulin we selected is more specific and can solve this problem well. On the other hand, our liquid crystal detection method has extremely high sensitivity and has great advantages for the detection of trace proteins in urine.

This exchange allowed us to see the achievability and practical application of our project from the aspect of technical application. It also let us have confidence in our projects.

Fig.3 Interview with the researches