Difference between revisions of "Team:KCL UK"

 
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{{:Team:KCL_UK/Templates/Header}}
 
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     <body>
 
     <body>
  
     <header>
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        <img src="https://static.igem.org/mediawiki/2018/0/08/T--KCL_UK--kclfinallogo.gif" alt="logo" class="logo">
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        <nav>
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            <ul>
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                <li><a href="https://2018.igem.org/Team:KCL_UK" class="nav-buttonmasks standalonenav">Home</a></li>
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                <li class="nav-buttonmasks">Team
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                  <a href="https://2018.igem.org/Team:KCL_UK/Team" class="dropdown-nav-buttonmasks dropdownone">Team Members</a>
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                    <a href="https://2018.igem.org/Team:KCL_UK/Collaborations" class="dropdown-nav-buttonmasks dropdowntwo">Collaborations</a>
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                </li>
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                <li class="nav-buttonmasks">Project
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                  <a href="https://2018.igem.org/Team:KCL_UK/Description" class="dropdown-nav-buttonmasks dropdownone">Description</a>
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                  <a href="https://2018.igem.org/Team:KCL_UK/InterLab" class="dropdown-nav-buttonmasks dropdowntwo">InterLab</a>
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                  <a href="https://2018.igem.org/Team:KCL_UK/Design" class="dropdown-nav-buttonmasks dropdownthree">Design</a>
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                  <a href="https://2018.igem.org/Team:KCL_UK/Model" class="dropdown-nav-buttonmasks dropdownfour">Model</a>
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                  <a href="https://2018.igem.org/Team:KCL_UK/Results" class="dropdown-nav-buttonmasks dropdownfive">Results</a>
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                  <a href="https://2018.igem.org/Team:KCL_UK/Attributions" class="dropdown-nav-buttonmasks dropdownsix">Attributions</a>
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                </li>
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                <li class="nav-buttonmasks">Parts
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                  <a href="https://2018.igem.org/Team:KCL_UK/Parts" class="dropdown-nav-buttonmasks dropdownone">Parts Overview</a>
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                  <a href="https://2018.igem.org/Team:KCL_UK/Basic_Part" class="dropdown-nav-buttonmasks dropdowntwo">Basic Parts</a>
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                  <a href="https://2018.igem.org/Team:KCL_UK/Composite_Part" class="dropdown-nav-buttonmasks dropdownthree">Composite Parts</a>
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                </li>
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                <a href="https://2018.igem.org/Team:KCL_UK/Safety" class="nav-buttonmasks standalonenav">Safety</a>
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                <li class="nav-buttonmasks">Human Practices
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                  <a href="https://2018.igem.org/Team:KCL_UK/Human_Practices" class="dropdown-nav-buttonmasks dropdownone" id="navadjust">Integrated HP</a>
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                  <a href="https://2018.igem.org/Team:KCL_UK/Public_Engagement" class="dropdown-nav-buttonmasks dropdowntwo" id="navadjust">Education and Engagement</a>
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                </li>
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                <a href="acknowledgements.html" class="nav-buttonmasks standalonenav">Acknowledgements</a>
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            </ul>
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        </nav>
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    </header>
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   <div class="loading">
 
   <div class="loading">
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     <section class="home-about">
 
     <section class="home-about">
 
         <div class="home-about-textbox">
 
         <div class="home-about-textbox">
             <h1>what are we doing?</h1>
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             <h1>What Have We Done?</h1>
             <p id="projectdescshort">We are developing a new technology platform based on 3'UTR sequence characterisation to control soluble protein expression in E.coli. <br> <br>We will use E.coli K12 to test our "Proof of Concept" Principle by engineering 3'UTR sequences (Sharma et al, 2011) to interact with either cytosolic proteins or 5'UTR sequences of our gene of interest: trxA and gor. Down regulation of these genes will be quantified by assessing quantitatively GFP signal. Efficiency of down regulation of genes will be quantified by assessing reaction kinetics of Alkaline Phosphatase (AP).</p>
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             <p id="projectdescshort">Our team have engineered a library of sRNA scaffolds that have the potential to be used as a tool in the understanding of sRNA functions such as regulation of protein expression. </br></br>
             <a href="#" class= "buttonmask buttonmask-accent">Full Project Description</a>
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Our project is based on a “Proof of Concept” principle and we have used E.coli K12 to test this. Regulation of gene expression has been quantitively assessed through GFP signalling. We have chosen to focus on sRNAs that target the 3’ UTR of mRNA.</br></br>
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We hope that future scientists will be able to use our novel tool as a way to use sRNAs to tackle issues involving sRNA interactions such as antibiotic resistance.
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    </p>
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             <a href="https://2018.igem.org/Team:KCL_UK/Description" class= "buttonmask buttonmask-accent">Full Project Description</a>
 
         </div>
 
         </div>
 
     </section>
 
     </section>
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             <img src="https://static.igem.org/mediawiki/2018/f/fe/T--KCL_UK--symposium.png" alt="portfolio item">
 
             <img src="https://static.igem.org/mediawiki/2018/f/fe/T--KCL_UK--symposium.png" alt="portfolio item">
 
             <figcaption class="port-desc">
 
             <figcaption class="port-desc">
                 <p>iGEM Symposium</p>
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                 <p>Integrated Human Practices</p>
                 <a href="" class="buttonmask buttonmask-accent buttonmask-small">See More</a>
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                 <a href="https://2018.igem.org/Team:KCL_UK/Human_Practices" class="buttonmask buttonmask-accent buttonmask-small">See More</a>
 
             </figcaption>
 
             </figcaption>
 
         </figure>
 
         </figure>
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             <figcaption class="port-desc">
 
             <figcaption class="port-desc">
 
                 <p>Bexley School Visit</p>
 
                 <p>Bexley School Visit</p>
                 <a href="" class="buttonmask buttonmask-accent buttonmask-small">See More</a>
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                 <a href="https://2018.igem.org/Team:KCL_UK/Public_Engagement" class="buttonmask buttonmask-accent buttonmask-small">See More</a>
 
             </figcaption>
 
             </figcaption>
 
         </figure>
 
         </figure>
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             <figcaption class="port-desc">
 
             <figcaption class="port-desc">
 
                 <p>Social Media</p>
 
                 <p>Social Media</p>
                 <a href="" class="buttonmask buttonmask-accent buttonmask-small">See More</a>
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                 <a href="https://www.instagram.com/igem_kcl/" class="buttonmask buttonmask-accent buttonmask-small">See More</a>
 
             </figcaption>
 
             </figcaption>
 
         </figure>
 
         </figure>
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             <figcaption class="port-desc">
 
             <figcaption class="port-desc">
 
                 <p>Lab Work</p>
 
                 <p>Lab Work</p>
                 <a href="" class="buttonmask buttonmask-accent buttonmask-small">See More</a>
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                 <a href="https://2018.igem.org/Team:KCL_UK/Design" class="buttonmask buttonmask-accent buttonmask-small">See More</a>
 
             </figcaption>
 
             </figcaption>
 
         </figure>
 
         </figure>

Latest revision as of 11:12, 17 October 2018

KCL iGEM

KCL iGEM

What Have We Done?

Our team have engineered a library of sRNA scaffolds that have the potential to be used as a tool in the understanding of sRNA functions such as regulation of protein expression.

Our project is based on a “Proof of Concept” principle and we have used E.coli K12 to test this. Regulation of gene expression has been quantitively assessed through GFP signalling. We have chosen to focus on sRNAs that target the 3’ UTR of mRNA.

We hope that future scientists will be able to use our novel tool as a way to use sRNAs to tackle issues involving sRNA interactions such as antibiotic resistance.

Full Project Description

Some of Our Work

portfolio item

Integrated Human Practices

See More
portfolio item

Bexley School Visit

See More
portfolio item

Social Media

See More
portfolio item

Lab Work

See More