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| − | <html>
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| − | <head>
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| − | <title>iGEM-bg</title>
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| − | <meta name="viewport" content="width=device-width, initial-scale=1">
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| − | </head>
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| − | <style>
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| − | body { margin:0px; background-color: #fff; max-width: 100%; min-width: 600px; font-family: Proxima Nova regular;}
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| − | /*------------Get rid of iGEM stuff----------------------------------*/
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| − | #home_logo, #sideMenu { display:none; }
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| − | #sideMenu, #top_title, .patrollink {display:none;}
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| − | #content { margin-left:0px; margin-top:-7px; padding:0px; width:100%;}
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| − | /*-------------------------------------------------------------------*/
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| − | /*--Top Navigation Styling--*/
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| − | #topnav {
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| − | text-align: center;
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| − | margin: 0 auto;
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| − | #topnav li ul{
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| − | position: relative;
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| − | display: none;
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| − | }
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| − | #topnav li ul li a {display:block !important;}
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| − | /* -- dropdown container-- */
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| − | .dropdown {
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| − | display: inline-block
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| − | }
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| − | /* --Dropdown button-- */
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| − | .dropdown .dropbtn {
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| − | font-size: 20px;
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| − | border: none;
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| − | color: white;
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| − | padding: 14px 16px;
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| − | background-color: inherit;
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| − | font-family: inherit;
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| − | margin: 0;
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| − | }
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| − | /*-- Dropdown content (hidden by default) --*/
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| − | .dropdown-content {
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| − | display: none;
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| − | position: absolute;
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| − | background-color: #eff1f2;
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| − | min-width: 200px;
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| − | border-radius: 7px;
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| − | box-shadow: 0px 8px 16px 0px rgba(0,0,0,0.2);
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| − | z-index: 1;
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| − | }
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| − | /*-- Links inside the dropdown-- */
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| − | .dropdown-content a {
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| − | color: black;
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| − | padding: 12px 16px;
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| − | text-decoration: none;
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| − | display: block;
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| − | text-align:left;
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| − | }
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| − | /*-- Add a grey background color to dropdown links on hover-- */
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| − | .dropdown-content a:hover {
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| − | background-color: #ddd;
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| − | }
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| − | /* --Show the dropdown menu on hover --*/
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| − | .dropdown:hover .dropdown-content {
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| − | display: block;
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| − | }
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| − | /*-----------Burger Menu Styling-------------*/
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| − | .topnav .burger {
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| − | display: none;
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| − | float: right;
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| − | margin-right: 20px;
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| − | z-index: 1;
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| − | color: #d9a900;
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| − | font-size: 20px;
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| − | }
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| − | .topnav .b-dropdown-content {
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| − | display: none;
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| − | border-radius: 7px;
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| − | .burger-content {
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| − | background-color: #f9f9f9;
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| − | border-radius: 7px;
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| − | box-shadow: 0px 8px 16px 0px rgba(0, 0, 0, 0.2);
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| − | z-index: 1;
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| − | width: 200px;
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| − | margin-top: 40px;
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| − | Float: none;
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| − | .burger-content div, .burger-content a {
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| − | text-decoration: none;
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| − | color: #525b65;
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| − | padding: 6px 8px;
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| − | text-decoration: none;
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| − | display: block;
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| − | text-align: left;
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| − | font-weight: bold;
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| − | overflow: hidden;
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| − | }
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| − | #topnav .b-dropdown:hover .b-dropdown-content {
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| − | display: inline-block;
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| − | #topnav .b-dropdown-content a:hover {
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| − | color: black;
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| − | #topnav .b-dropdown-content {
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| − | background-color: #f9f9f9;
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| − | min-width: 150px;
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| − | margin-left: 200px;
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| − | z-index: 1;
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| − | input[type=checkbox]{
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| − | input[type=checkbox]:checked ~ .burger-content {
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| − | @media screen and (max-width:750px) {
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| − | #topnav .dropdown .dropbtn {
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| − | #topnav {
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| − | #topnav li.burger {
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| − | display: flex;
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| − | }
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| − | /*-------------------------------------------*/
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| − |
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| − | /*--alignment--*/
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| − | .content {
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| − | margin:0 auto;
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| − | background-color:#002855;
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| − | }
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| − | .contentb {
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| − | margin:0% auto;
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| − | background-color:#002855;
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| − | white-space: nowrap ;
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| − | overflow: hidden;
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| − | width: 100%;
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| − | }
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| − | .logos {
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| − | width: 33%;
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| − | vertical-align: middle;
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| − | display: inline-block;
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| − | }
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| − | .logos img {
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| − | text-align: center;
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| − | display: table-cell;
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| − | vertical-align: middle;
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| − | width: 0 auto;
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| − | }
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| − |
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| − | /*------------------------Shapes-------------------------------------------*/
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| − | .rectangleb{
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| − | height: 600;
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| − | width: 100%;
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| − | background-color: #002855;
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| − | position:relative;
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| − | }
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| − | .triangleb {
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| − | background-color: #002855;
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| − | width: 100%;
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| − | min-width: 600px;
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| − | position: absolute;
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| − | margin: 0;
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| − | margin-top: -0.5px;
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| − | }
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| − | .triangleb:after {
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| − | content: "";
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| − | position: absolute;
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| − | min-width: 600px;
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| − | top: 100%;
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| − | left: 0;
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| − | right: 0;
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| − | padding-bottom: 10%;
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| − | background-color: #002855;
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| − | clip-path: polygon(0% 0%, 100% 0%, 50% 100%);
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| − | }
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| − |
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| − | .trianglew{
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| − | background-color: #fff;
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| − | width: 100%;
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| − | min-width: 600px;
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| − | position: absolute;
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| − | margin: 0;
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| − | margin-top: -0.5px;
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| − | }
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| − |
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| − | .trianglew:after {
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| − | content: "";
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| − | position: absolute;
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| − | top: 100%;
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| − | left: 0;
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| − | right: 0;
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| − | padding-bottom: 10%;
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| − | background-color: #fff;
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| − | clip-path: polygon(0% 0%, 100% 0%, 50% 100%);
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| − | }
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| − | .spacer {
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| − | height: 10vw;
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| − | }
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| − | .spacerw {
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| − | height: 10vw;
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| − | }
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| − |
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| − | </style>
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| − |
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| − | <body>
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| − | <div class="content">
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| − | <div class="contentb">
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| − | <!-- Page content -->
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| − | <div style='padding-top: 50px;'></div>
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| − | <!--______________UC Davis logo____________-->
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| − |
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| − | <div class="logos" style="background-color: #002855;">
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| − | <a href="http://ucdavis.com">
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| − | <img src="https://static.igem.org/mediawiki/2018/a/a5/T--UC_Davis--whitelogo.png" alt="uc davis logo" style="margin-left: auto;margin-right:auto; width: 50%;" Padding: "0";>
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| − | </a>
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| − | </div>
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| − |
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| − | <!--_____________Cenozoic logo_____________-->
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| − |
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| − | <div class="logos" style="background-color: #002855">
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| − | <a href="https://2018.igem.org/Team:UC_Davis">
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| − | <img src="https://static.igem.org/mediawiki/2018/1/1b/T--UC_Davis--DNA_refined.png" alt="Cenozoic logo" style="width: 80%; margin-left: auto;margin-right: auto;"Padding: "0";>
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| − | </a>
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| − | </div>
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| − |
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| − |
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| − | <!--______________iGEM logo____________-->
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| − |
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| − | <div class="logos" style="background-color: #002855">
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| − | <a href="https://2018.igem.org">
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| − | <img src="https://static.igem.org/mediawiki/2018/2/2b/T--UC_Davis--iGEM.png" alt="iGEM logo" style="width: 40%; margin-left: auto;margin-right: auto;" ;Padding: "0";>
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| − | </a>
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| − | </div>
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| − | </div>
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| − | <div style='padding-top: 130px;'></div>
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| − |
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| − | <!--______________Top Navigation Bar____________-->
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| − | <ul class="topnav" id="topnav">
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| − |
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| − | <!--______________Project____________-->
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| − | <div class="dropdown">
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| − | <button class="dropbtn">PROJECT</button>
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| − | <div class="dropdown-content">
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| − | <a href="#">Design</a>
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| − | <a href="#">Results</a>
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| − | <a href="#">Modelling</a>
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| − | <a href="#">InterLab</a>
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| − |
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| − | </div>
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| − | </div>
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| − | <!--______________Human Resources____________-->
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| − | <div class="dropdown">
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| − | <button class="dropbtn">HUMAN RESOURCES</button>
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| − | <div class="dropdown-content">
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| − | <a href="#">Motivation</a>
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| − | <a href="#">Outreach</a>
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| − | <a href="#">Policy</a>
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| − | </div>
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| − | </div>
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| − | <!--______________Parts____________-->
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| − | <div class="dropdown">
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| − | <button class="dropbtn">PARTS</button>
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| − | <div class="dropdown-content">
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| − | <a href="#">Basic</a>
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| − | <a href="#">Composite</a>
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| − | <a href="#">Parts Collection</a>
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| − |
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| − | </div>
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| − | </div>
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| − | <!--______________Lab____________-->
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| − | <div class="dropdown">
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| − | <button class="dropbtn">LAB WORK</button>
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| − | <div class="dropdown-content">
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| − | <a href="#">Notebook</a>
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| − | <a href="#">Methods and Materials</a>
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| − | <a href="#">Safety</a>
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| − |
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| − | </div>
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| − | </div>
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| − | <!--______________Acknowledgements____________-->
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| − | <div class="dropdown">
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| − | <button class="dropbtn">TEAM</button>
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| − | <div class="dropdown-content">
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| − | <a href="#">Meet the Team</a>
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| − | <a href="#">Advisors</a>
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| − | <a href="#">Sposors</a>
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| − | </div>
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| − | </div>
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| − | <!--______________Achievements____________-->
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| − | <div class="dropdown">
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| − | <button class="dropbtn">ACHIEVEMENTS</button>
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| − | <div class="dropdown-content">
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| − | <a href="#">Medal Requirements</a>
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| − | <a href="#">Outreach</a>
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| − | </div>
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| − | </div>
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| − |
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| − |
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| − | <!--___________________________________Burger Menu____________________________________________-->
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| − | <li class="burger"><input type="checkbox" id="b-control"><label for="b-control">☰</label>
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| − | <div class="burger-content">
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| − | <div class="b-dropdown"><a href="Project" class="b-dropdown-main">Project</a>
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| − | <div class="b-dropdown-content">
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| − | <a href="#">Design</a>
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| − | <a href="#">Results</a>
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| − | <a href="#">Modelling</a>
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| − | <a href="#">InterLab</a>
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| − | </div>
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| − | </div>
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| − | <div class="b-dropdown"><a href="Practices" class="b-dropdown-main"> Human Practices</a>
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| − | <div class="b-dropdown-content">
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| − | <a href="#">Motivation</a>
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| − | <a href="#">Outreach</a>
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| − | <a href="#">Policy</a>
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| − | </div>
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| − | </div>
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| − | <div class="b-dropdown"><a href="Parts" class="b-dropdown-main">Parts</a>
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| − | <div class="b-dropdown-content">
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| − | <a href="#">Basic</a>
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| − | <a href="#">Composite</a>
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| − | <a href="#">Parts Collection</a>
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| − | </div>
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| − | </div>
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| − | <div class="b-dropdown"><a href="Lab" class="b-dropdown-main">Lab Work</a>
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| − | <div class="b-dropdown-content">
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| − | <a href="#">Notebook</a>
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| − | <a href="#">Methods and Materials</a>
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| − | <a href="#">Safety</a>
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| − | </div>
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| − | </div>
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| − | <div class="b-dropdown b-Acknowledgements"><a href="Acknowledgements" class="b-dropdown-main">Team</a>
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| − | <div class="b-dropdown-content">
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| − | <a href="#">Meet the Team</a>
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| − | <a href="#">Advisors</a>
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| − | <a href="#">Sponsors</a>
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| − | </div>
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| − | </div>
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| − | <div class="b-dropdown"><a href="Parts" class="b-dropdown-main">Achievements</a>
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| − | <div class="b-dropdown-content">
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| − | <a href="#">Medal Requirements</a>
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| − | <a href="#">Outreach</a>
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| − | </div>
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| − | </div>
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| − | </div>
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| − | </span>
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| − | </li>
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| − | </ul>
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| − | <!--__________________________________________________________________________________________-->
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| − |
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| − | </ul>
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| − | </div>
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| − |
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| − | <!--______Triangle and Spacing______-->
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| − | <div class="triangleb"></div>
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| − | <div class="spacer"></div>
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| − |
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| − | <!--_______CONTENT Arrow 1______________-->
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| − |
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| − | <center>
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| − | <div style = ' padding-right: 100PX; padding-left: 60PX; padding-bottom: 20px;padding-top: 100px; font-size: 30px; color: #d9a900'; ><b>Mammailian Cell Based Biosensor For Physiological Effects Of Toxins</b></div>
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| − | </center>
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| − | <div style='padding-top: 30px;'></div>
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| − |
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| − | <div style = 'padding-right: 100PX; padding-left: 100PX; text-indent: 50px;line-height: 25px; font-size: 18px' >
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| − | After visiting the Yurok Tribe, it became clear that to have a real positive impact regarding their problems with pollution and health, it would be necessary to draw a clear narrative between sources of pollution, a specific toxin in the environment, a high quality field test, a causal effect on human health, and a specific policy change.
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| − | <p style='font-size: 18px'>Polluters –> Environment (Field Test) –> Human Disease –> Policy Change –| </p>
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| − | <p style='font-size: 18px'> Polluters For best outcomes, every link in this chain needs to be well documented and backed by substantial evidence/data. It needs to be clear which organizations are responsible for introducing which toxins into the environment, that they are present in meaningful concentrations in the environment, that these toxins have a known causal effect on human disease, and what set of policy changes can help improve public health.</P>
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| − | </div>
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| − | <!--_______CONTENT Arrow 2______________-->
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| − |
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| − | <div class="rectangleb">
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| − | <!--______Triangle and Spacing______-->
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| − | <div class="trianglew"></div>
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| − | <div class="spacerw"></div>
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| − |
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| − | <!-- Page content -->
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| − | <div style='padding-top: 25px;'></div>
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| − | <center>
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| − | <div style = 'padding-left: 10PX; padding-bottom: 20px;padding-top: 20px; font-size: 30px; color: #d9a900'; ><b>Process</b></div>
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| − | </center>
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| − | <div style='padding-top: 30px;'></div>
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| − | <div style = 'padding-right: 100PX; padding-left: 100PX;padding-bottom: 60px; text-indent:50px ;line-height: 25px; color: #fff; font-size: 18px'; >
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| − | After initially focusing on the possibility of developing a new field test to help detect COCs in the environment, upon further research, it was determined that the current state
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| − | of the art field tests, ELISA immunoassays, are of high quality and effectiveness. In light of this finding, we determined that our efforts were best spent studying the effect of COCs, including chemicals which have not been previously studied in detail, on the physiological health of mammalian cells.
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| − | </div>
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| − | </div>
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| − | <!--______Triangle and Spacing______-->
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| − | <div class="triangleb"></div>
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| − | <!--_______CONTENT Arrow 3_____________-->
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| − |
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| − | <img src="https://static.igem.org/mediawiki/2018/9/93/T--UC_Davis--Plates.jpg" alt="Cenozoic logo" style="margin-left: auto;margin-right: auto; z-index:1;"width="100%"; height="560px"; Padding: "0";>
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| − | <!--_______CONTENT Arrow 4_____________-->
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| − | <div class="rectangleb">
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| − | <!--______Triangle and Spacing______-->
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| − | <div class="trianglew"></div>
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| − | <div class="spacer"></div>
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| − | <div style='padding-top: 25px;'></div>
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| − | <center>
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| − | <div style = 'padding-left: 10PX; padding-bottom: 20px;padding-top: 20px; font-size: 27px; color: #d9a900'; ><b>Limitations</b></div>
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| − | </center>
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| − | <div style='padding-top: 30px;'></div>
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| − | <div style = 'padding-right: 100PX; padding-left: 100PX;padding-bottom: 60px; text-indent:50px ;line-height: 25px; color: #fff; font-size: 18px'; >
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| − | A limitation of our research is that we will not be able to show a definitive causal link between COCs and human disease, but it is our intention to find links between COCs and physiological stress in mammalian systems, with the hope that our findings may motivate and inform further studies to find out if there is a causal link between these COCs and human disease.
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| − | </div>
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| − | </div>
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| − | <div class="triangleb"></div>
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| − | <div class="spacer"></div>
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| − | <div style='padding-top: 30px;'></div>
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| − | <center>
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| − | <div style = 'padding-left: 10PX; padding-bottom: 20px;padding-top: 20px; font-size: 30px; color: #d9a900'; ><b>Extension</b></div>
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| − | </center>
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| − | <div style='padding-top: 30px;'></div>
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| − | <div style = 'padding-right: 100PX; padding-left: 100PX; text-indent: 50px;line-height: 25px; font-size: 18px' >
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| − | A possible extension of our research would be to determine the effect of multiple COCs on the physiological health of mammalian cells. This would be of value in assessing and creating sane standards for pollution, as organisms in the natural environment are exposed to a variety of COCs at once, which may not have been previously screened in conjunction with each other. A possible finding from this might be that COC “A,” at a concentration below what is currently considered to be harmful, in the presence of COC “B,” also at a concentration below what is currently considered to be harmful, interact together to trigger a response associated with stress in mammalian cells.
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| − | </div>
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| − | <div style='padding-top: 30px;'></div>
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| − | </body>
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| − | </html>
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