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| <div id="contents"></div> | | <div id="contents"></div> |
| <div id="article"> | | <div id="article"> |
| + | <div class="mainText"> |
| + | <p>We carried out human practices from the perspectives of the public, doctors and researchers, and get |
| + | different feedback to promote our projects further.</p> |
| + | </div> |
| + | |
| <div> | | <div> |
− | <h2 class="title">Brochure Designing and Preaching</h2> | + | <h2 class="title">Interview with the public</h2> |
| <div class="mainText"> | | <div class="mainText"> |
− | <p>Our team of practice designed a brochure on knowledge about kidney disease carefully in order to | + | <p>The team members conducted a social survey. We found that many people are too busy to go to the |
− | make more patients with diabetes and hypertension recognize the dangers of the development of | + | hospital for regular medical examinations. People pay less attention to the health of the |
− | chronic kidney disease(CKD), and help the old to prevent CKD, hypertension and diabetes early.In | + | kidneys. We want to change this situation by using our portable urine testing equipment. |
− | July 2018, we held a knowledge preaching about the early prevention of CKD in Jianshan Community | + | According to the practical data, we have found that more than 80% of respondents are willing to |
− | of Dalian ,and at the same time, we distributed our brochure designed by ourselves.In a summer | + | use our products. Considering about the binding time of antigen and antibody and the |
− | house in the community, we distributed the brochure to some aunts,which lead them to understand | + | corresponding time of liquid crystal, the acceptable waiting time for respondents is about 40 |
− | the dangers of kidney disease, the causes of kidney disease, and methods for preventing early
| + | minutes. We will shorten the waiting time under the condition of ensuring the accuracy of |
− | kidney disease. Besides, we answered many questions about diabetes and high blood pressure asked | + | measurement in the subsequent experiments.</p> |
− | by those aunts patiently. After we had a further communication with community residents by
| + | <p>This interview and sample survey enriched our project background data. We analyzed and processed |
− | interviewing them, we clearly felt that they had a deeper understanding of the dangers of CKD | + | the data obtained from the survey and found that our project does have certain market demand. |
− | and the importance of its early prevention,which means our practice is successful enough.</p> | + | This also laid the foundation for our subsequent optimization of experimental conditions.</p> |
| <table class="img"> | | <table class="img"> |
| <tr> | | <tr> |
− | <td><img src="https://static.igem.org/mediawiki/2018/0/0c/T--DLUT_China_B--HumanPractice6.jpg"></td> | + | <td><img src="https://static.igem.org/mediawiki/2018/b/b4/T--DLUT_China_B--HumanPractice14.jpg"> |
− | <td><img src="https://static.igem.org/mediawiki/2018/1/17/T--DLUT_China_B--HumanPractice7.jpg"></td> | + | </td> |
| </tr> | | </tr> |
| <tr> | | <tr> |
− | <td><img src="https://static.igem.org/mediawiki/2018/3/38/T--DLUT_China_B--HumanPractice8.jpg"></td> | + | <td> |
− | <td><img src="https://static.igem.org/mediawiki/2018/f/f1/T--DLUT_China_B--HumanPractice9.jpg"></td> | + | <p class="footnote">Fig.1 interview with the public</p> |
| + | </td> |
| </tr> | | </tr> |
| </table> | | </table> |
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| <div> | | <div> |
− | <h2 class="title">Interviews with Doctors</h2> | + | <h2 class="title">Interviews with doctors</h2> |
| <div class="mainText"> | | <div class="mainText"> |
− | <p>During the summer vacation, the team members carried out practical activities throughout the | + | <p>In August 2018, the team members went to Linyi City People's Hospital of Shandong Province to |
− | country and went to the hospital to interview the specialists in the kidney department. We not
| + | interview Dr. Liu Haijun, a specialist in nephrology. We knew that early diagnosis and treatment |
− | only understand the serious situation that diabetes and hypertension cause the proportion of | + | are extremely important in delaying the development of kidney disease. Only when the patient has |
− | chronic kidney disease in China to rise year by year, but also know that patients with diabetes
| + | obvious symptoms will he go to the hospital for an examination. But they may already have |
− | have no early and staged awareness. When patients come to the hospital for treatment, most of | + | entered the dominant diabetic nephropathy (overtDN).</p> |
− | them have obvious symptoms and enter CKD phase III, and early visits and treatments are
| + | <p>Blood test is the most common diagnosis method of the hospital currently. It takes ¥48 to test |
− | extremely important for the development of delayed kidney disease. At present, the diagnosis | + | the blood β<sub>2</sub>-microglobulin. However, Dr.Liu said that if a portable urine test method can be |
− | method of the hospital is mainly blood test, but the doctor said that if a non-invasive portable
| + | developed, it can not only alleviate the pain of blood drawing, but also greatly improve the |
− | detection method through urine can be developed, it can not only alleviate the pain of blood
| + | awareness of diabetes patients and the rate of early visits.</p> |
− | drawing, but also have a very high rate of early detection and treatment. In this interview, we
| + | <p>In this interview we exchanged ideas with doctors, and we have learned that from a clinical |
− | learned the importance and urgent needs of early detection in the treatment of chronic kidney | + | perspective, our project is more suitable for use at home. It can greatly arouse the awareness |
− | disease and the importance of improving the awareness of early treatment of patients, and more | + | of early patients, which can indirectly improve the diagnosis rate and provide the best time for |
− | deeply recognized the practicality and usefulness of our projects.</p> | + | treatment.</p> |
| <table class="img"> | | <table class="img"> |
| <tr> | | <tr> |
− | <td><img src="https://static.igem.org/mediawiki/2018/9/9c/T--DLUT_China_B--HumanPractice10.jpg"></td> | + | <td><img src="https://static.igem.org/mediawiki/2018/9/9c/T--DLUT_China_B--HumanPractice10.jpg"> |
− | <td><img src="https://static.igem.org/mediawiki/2018/d/d4/T--DLUT_China_B--HumanPractice11.jpg"></td> | + | </td> |
| + | <td><img src="https://static.igem.org/mediawiki/2018/d/d4/T--DLUT_China_B--HumanPractice11.jpg"> |
| + | </td> |
| + | </tr> |
| + | <tr> |
| + | <td colspan="2"> |
| + | <p class="footnote">Fig.2 Interviews with doctors</p> |
| + | </td> |
| </tr> | | </tr> |
| </table> | | </table> |
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| <div> | | <div> |
− | <h2 class="title">Product Research, Fun Marketing</h2> | + | <h2 class="title">Interview with the researches in the Dalian Institute of Chemical Physics(DICP)</h2> |
| <div class="mainText"> | | <div class="mainText"> |
− | <p>In order to further understand the market demand for our products, the patient's recognition of | + | <p>In order to better understand the current situation of urine testing, the team members came to |
− | products and their performance expectations for the products, we designed a questionnaire of the | + | the Research Group of Biomolecular Efficient Separation and Characterization of Dalian Institute |
− | product. And to help people understand the superiority of our products, we have designed a | + | of Chemical Physics, Chinese Academy of Sciences in October 2018. We exchanged ideas with |
− | product-based storyline, and we hope to attract more people who interest in our products in the | + | researcher Yuan Huiming. Researcher Yuan said that the main problem in urine testing is to |
− | form of anthropomorphic storytelling and made our content of the project is impressive.</p> | + | eliminate interference from other proteins in the urine. The nanobody of β<sub>2</sub>-microglobulin we |
| + | selected is more specific and can solve this problem well. On the other hand, our liquid crystal |
| + | detection method has extremely high sensitivity and has great advantages for the detection of |
| + | trace proteins in urine.</p> |
| + | <p>This exchange allowed us to see the achievability and practical application of our project from |
| + | the aspect of technical application. It also let us have confidence in our projects.</p> |
| <table class="img"> | | <table class="img"> |
| <tr> | | <tr> |
− | <td><img src="https://static.igem.org/mediawiki/2018/c/c4/T--DLUT_China_B--HumanPractice12.jpg"></td> | + | <td><img src="https://static.igem.org/mediawiki/2018/c/c4/T--DLUT_China_B--HumanPractice12.jpg"> |
− | <td><img src="https://static.igem.org/mediawiki/2018/3/31/T--DLUT_China_B--HumanPractice13.jpg"></td> | + | </td> |
| + | <td><img src="https://static.igem.org/mediawiki/2018/3/31/T--DLUT_China_B--HumanPractice13.jpg"> |
| + | </td> |
| + | </tr> |
| + | <tr> |
| + | <td colspan="2"> |
| + | <p class="footnote">Fig.3 Interview with the researches</p> |
| + | </td> |
| </tr> | | </tr> |
| </table> | | </table> |