Difference between revisions of "Team:DLUT China B/Human Practices"

(Prototype team page)
 
m
 
(5 intermediate revisions by the same user not shown)
Line 1: Line 1:
−
{{DLUT_China_B}}
+
<html lang="en">
−
<html>
+
<head>
−
 
+
    <meta charset="UTF-8">
−
<div class="column full_size judges-will-not-evaluate">
+
    <meta http-equiv="X-UA-Compatible" content="IE=edge">
−
<h3>★  ALERT! </h3>
+
    <title>Human Practices</title>
−
<p>This page is used by the judges to evaluate your team for the <a href="https://2018.igem.org/Judging/Medals">medal criterion</a> or <a href="https://2018.igem.org/Judging/Awards"> award listed below</a>. </p>
+
    <link rel="stylesheet" href="https://2018.igem.org/wiki/index.php?title=Template:DLUT_China_B/css/style.css&action=raw&ctype=text/css">
−
<p> Delete this box in order to be evaluated for this medal criterion and/or award. See more information at <a href="https://2018.igem.org/Judging/Pages_for_Awards"> Instructions for Pages for awards</a>.</p>
+
    <link rel="stylesheet" href="https://2018.igem.org/wiki/index.php?title=Template:DLUT_China_B/css/nav.css&action=raw&ctype=text/css">
−
</div>
+
    <link rel="stylesheet" href="https://2018.igem.org/wiki/index.php?title=Template:DLUT_China_B/css/fontawesome.css&action=raw&ctype=text/css">
−
 
+
    <link rel="stylesheet" href="https://2018.igem.org/wiki/index.php?title=Template:DLUT_China_B/css/contents.css&action=raw&ctype=text/css">
−
 
+
</head>
−
<div class="clear"></div>
+
<body>
−
 
+
<div id="dlutb">
−
 
+
    <div id="moduleHeader">
−
 
+
        <div id="nav"></div>
−
<div class="column full_size">
+
        <div id="background" class="humanPractices"></div>
−
 
+
        <div class="moduleTitle">Human Practices</div>
−
<h1>Human Practices</h1>
+
    </div>
−
<p>
+
−
At iGEM we believe societal considerations should be upfront and integrated throughout the design and execution of synthetic biology projects. “Human Practices” refers to iGEM teams’ efforts to actively consider how the world affects their work and the work affects the world. Through your Human Practices activities, your team should demonstrate how you have thought carefully and creatively about whether your project is responsible and good for the world. We invite you to explore issues relating (but not limited) to the ethics, safety, security, and sustainability of your project, and to show how this exploration feeds back into your project purpose, design and execution.
+
−
</p>
+
−
 
+
−
 
+
−
 
+
−
<p>For more information, please see the <a href="https://2018.igem.org/Human_Practices">Human Practices Hub</a>. There you will find:</p>
+
−
+
−
<ul>
+
−
<li> an <a href="https://2018.igem.org/Human_Practices/Introduction">introduction</a> to Human Practices at iGEM </li>
+
−
<li>tips on <a href="https://2018.igem.org/Human_Practices/How_to_Succeed">how to succeed</a> including explanations of judging criteria and advice about how to conduct and document your Human Practices work</li>
+
−
<li>descriptions of <a href="https://2018.igem.org/Human_Practices/Examples">exemplary work</a> to inspire you</li>
+
−
<li>links to helpful <a href="https://2018.igem.org/Human_Practices/Resources">resources</a></li>
+
−
<li>And more! </li>
+
−
</ul>
+
−
+
−
 
+
−
 
+
−
 
+
−
 
+
−
<p>On this page, your team should document all of your Human Practices work and activities. You should write about the Human Practices topics you considered in your project, document any activities you conducted to explore these topics (such as engaging with experts and stakeholders), describe why you took a particular approach (including referencing any work you built upon), and explain if and how you integrated takeaways from your Human Practices work back into your project purpose, design and/or execution. </p>
+
−
+
−
<p>If your team has gone above and beyond in work related to safety, then you should document this work on your Safety wiki page and provide a description and link on this page. If your team has developed education and public engagement efforts that go beyond a focus on your particular project, and for which would like to nominate your team for the Best Education and Public Engagement Special Prize, you should document this work on your Education and Education wiki page and provide a description and link here. </p>
+
−
</div>
+
−
+
−
<div class="clear"></div>
+
−
 
+
−
+
−
<div class="column full_size">
+
−
<div class="highlight decoration_background">
+
−
<p>The iGEM judges will review this page to assess whether you have met the Silver and/or Gold medal requirements based on the Integrated Human Practices criteria listed below. If you nominate your team for the <a href="https://2018.igem.org/Judging/Awards">Best Integrated Human Practices Special Prize</a> by filling out the corresponding field in the <a href="https://2018.igem.org/Judging/Judging_Form">judging form</a>, the judges will also review this page to consider your team for that prize.
+
−
</p>
+
−
</div>
+
−
</div>
+
−
 
+
−
<div class="clear extra_space"></div>
+
−
 
+
−
 
+
−
 
+
−
<div class="column full_size">
+
−
+
−
<h3>Silver Medal Criterion #3</h3>
+
−
<p>Convince the judges you have thought carefully and creatively about whether your work is responsible and good for the world. Document how you have investigated these issues and engaged with your relevant communities, why you chose this approach, and what you have learned. Please note that surveys will not fulfill this criteria unless you follow scientifically valid methods. </p>
+
−
 
+
−
 
+
−
<h3>Gold Medal Criterion #1</h3>
+
−
<p>Expand on your silver medal activity by demonstrating how you have integrated the investigated issues into the purpose, design and/or execution of your project. Document how your project has changed based upon your human practices work.
+
−
</p>
+
−
</div>
+
−
 
+
  
 +
    <div id="mainBody">
 +
        <div id="contents"></div>
 +
        <div id="article">
 +
            <div class="mainText">
 +
                <p>We carried out human practices from the perspectives of the public, doctors and researchers, and get
 +
                    different feedback to promote our projects further.</p>
 +
            </div>
  
−
<div class="clear extra_space"></div>
+
            <div>
 +
                <h2 class="title">Interview with the public</h2>
 +
                <div class="mainText">
 +
                    <p>The team members conducted a social survey. We found that many people are too busy to go to the
 +
                        hospital for regular medical examinations. People pay less attention to the health of the
 +
                        kidneys. We want to change this situation by using our portable urine testing equipment.
 +
                        According to the practical data, we have found that more than 80% of respondents are willing to
 +
                        use our products. Considering about the binding time of antigen and antibody and the
 +
                        corresponding time of liquid crystal, the acceptable waiting time for respondents is about 40
 +
                        minutes. We will shorten the waiting time under the condition of ensuring the accuracy of
 +
                        measurement in the subsequent experiments.</p>
 +
                    <p>This interview and sample survey enriched our project background data. We analyzed and processed
 +
                        the data obtained from the survey and found that our project does have certain market demand.
 +
                        This also laid the foundation for our subsequent optimization of experimental conditions.</p>
 +
                    <table class="img">
 +
                        <tr>
 +
                            <td><img src="https://static.igem.org/mediawiki/2018/b/b4/T--DLUT_China_B--HumanPractice14.jpg">
 +
                            </td>
 +
                        </tr>
 +
                        <tr>
 +
                            <td>
 +
                                <p class="footnote">Fig.1 interview with the public</p>
 +
                            </td>
 +
                        </tr>
 +
                    </table>
 +
                </div>
 +
            </div>
  
 +
            <div>
 +
                <h2 class="title">Interviews with doctors</h2>
 +
                <div class="mainText">
 +
                    <p>In August 2018, the team members went to Linyi City People's Hospital of Shandong Province to
 +
                        interview Dr. Liu Haijun, a specialist in nephrology. We knew that early diagnosis and treatment
 +
                        are extremely important in delaying the development of kidney disease. Only when the patient has
 +
                        obvious symptoms will he go to the hospital for an examination. But they may already have
 +
                        entered the dominant diabetic nephropathy (overtDN).</p>
 +
                    <p>Blood test is the most common diagnosis method of the hospital currently. It takes ¥48 to test
 +
                        the blood β<sub>2</sub>-microglobulin. However, Dr.Liu said that if a portable urine test method can be
 +
                        developed, it can not only alleviate the pain of blood drawing, but also greatly improve the
 +
                        awareness of diabetes patients and the rate of early visits.</p>
 +
                    <p>In this interview we exchanged ideas with doctors, and we have learned that from a clinical
 +
                        perspective, our project is more suitable for use at home. It can greatly arouse the awareness
 +
                        of early patients, which can indirectly improve the diagnosis rate and provide the best time for
 +
                        treatment.</p>
 +
                    <table class="img">
 +
                        <tr>
 +
                            <td><img src="https://static.igem.org/mediawiki/2018/9/9c/T--DLUT_China_B--HumanPractice10.jpg">
 +
                            </td>
 +
                            <td><img src="https://static.igem.org/mediawiki/2018/d/d4/T--DLUT_China_B--HumanPractice11.jpg">
 +
                            </td>
 +
                        </tr>
 +
                        <tr>
 +
                            <td colspan="2">
 +
                                <p class="footnote">Fig.2 Interviews with doctors</p>
 +
                            </td>
 +
                        </tr>
 +
                    </table>
 +
                </div>
 +
            </div>
  
 +
            <div>
 +
                <h2 class="title">Interview with the researches in the Dalian Institute of Chemical Physics(DICP)</h2>
 +
                <div class="mainText">
 +
                    <p>In order to better understand the current situation of urine testing, the team members came to
 +
                        the Research Group of Biomolecular Efficient Separation and Characterization of Dalian Institute
 +
                        of Chemical Physics, Chinese Academy of Sciences in October 2018. We exchanged ideas with
 +
                        researcher Yuan Huiming. Researcher Yuan said that the main problem in urine testing is to
 +
                        eliminate interference from other proteins in the urine. The nanobody of β<sub>2</sub>-microglobulin we
 +
                        selected is more specific and can solve this problem well. On the other hand, our liquid crystal
 +
                        detection method has extremely high sensitivity and has great advantages for the detection of
 +
                        trace proteins in urine.</p>
 +
                    <p>This exchange allowed us to see the achievability and practical application of our project from
 +
                        the aspect of technical application. It also let us have confidence in our projects.</p>
 +
                    <table class="img">
 +
                        <tr>
 +
                            <td><img src="https://static.igem.org/mediawiki/2018/c/c4/T--DLUT_China_B--HumanPractice12.jpg">
 +
                            </td>
 +
                            <td><img src="https://static.igem.org/mediawiki/2018/3/31/T--DLUT_China_B--HumanPractice13.jpg">
 +
                            </td>
 +
                        </tr>
 +
                        <tr>
 +
                            <td colspan="2">
 +
                                <p class="footnote">Fig.3 Interview with the researches</p>
 +
                            </td>
 +
                        </tr>
 +
                    </table>
 +
                </div>
 +
            </div>
 +
        </div>
 +
    </div>
  
−
<div class="column full_size">
+
    <div id="footer">
−
<h3>Best Integrated Human Practices Special Prize</h3>
+
        <div id="address">
 +
            <h3><i class="fas fa-map-marker-alt"></i> Address</h3>
 +
            <p>No.2 Linggong Road, Ganjingzi District, Dalian City, Liaoning Province, P.R.C., 116024</p>
 +
            <h3><i class="fas fa-at"></i> E-mail</h3>
 +
            <p>igem_dlut_china_B#163.com (Please replace # with @)</p>
 +
        </div>
 +
        <div id="follow">
 +
            <h3>Follow Us</h3>
 +
            <div id="platformName">
 +
                <p><i class="fab fa-weixin"></i> WeChat</p>
 +
                <p></p>
 +
                <p><i class="fab fa-weibo"></i> Weibo</p>
 +
            </div>
 +
            <div id="qrCode">
 +
                <div><img src="https://static.igem.org/mediawiki/2018/c/c6/T--DLUT_China_B--wechat.png" width="100"></div>
 +
                <div></div>
 +
                <div><img src="https://static.igem.org/mediawiki/2018/6/6b/T--DLUT_China_B--weibo.png" width="100"></div>
  
−
<p>To compete for the Best Integrated Human Practices prize, please describe your work on this page and also fill out the description on the judging form. </p>
+
            </div>
 +
        </div>
 +
    </div>
  
−
<p>How does your project affect society and how does society influence the direction of your project? How might ethical considerations and stakeholder input guide your project purpose and design and the experiments you conduct in the lab? How does this feedback enter into the process of your work all through the iGEM competition? Document a thoughtful and creative approach to exploring these questions and how your project evolved in the process to compete for this award!</p>
+
    <div id="back" class="btn">
−
<p>You must also delete the message box on the top of this page to be eligible for this prize.</p>
+
        <i class="fas fa-angle-up"></i>
 +
    </div>
  
 +
    <script src="https://2018.igem.org/wiki/index.php?title=Template:DLUT_China_B/js/script.js&action=raw&ctype=text/javascript"></script>
 +
    <script src="https://2018.igem.org/wiki/index.php?title=Template:DLUT_China_B/js/contents.js&action=raw&ctype=text/javascript"></script>
 +
    <script>
 +
        $(document).ready(function () {
 +
            $(window).scroll(function () {
 +
                topToggle();
 +
            });
 +
            $(window).scroll(function () {
 +
                contentsAnchor();
 +
            });
 +
        });
 +
    </script>
 
</div>
 
</div>
 +
</body>
 +
</html>

Latest revision as of 02:47, 18 October 2018

Human Practices

Human Practices

We carried out human practices from the perspectives of the public, doctors and researchers, and get different feedback to promote our projects further.

Interview with the public

The team members conducted a social survey. We found that many people are too busy to go to the hospital for regular medical examinations. People pay less attention to the health of the kidneys. We want to change this situation by using our portable urine testing equipment. According to the practical data, we have found that more than 80% of respondents are willing to use our products. Considering about the binding time of antigen and antibody and the corresponding time of liquid crystal, the acceptable waiting time for respondents is about 40 minutes. We will shorten the waiting time under the condition of ensuring the accuracy of measurement in the subsequent experiments.

This interview and sample survey enriched our project background data. We analyzed and processed the data obtained from the survey and found that our project does have certain market demand. This also laid the foundation for our subsequent optimization of experimental conditions.

Fig.1 interview with the public

Interviews with doctors

In August 2018, the team members went to Linyi City People's Hospital of Shandong Province to interview Dr. Liu Haijun, a specialist in nephrology. We knew that early diagnosis and treatment are extremely important in delaying the development of kidney disease. Only when the patient has obvious symptoms will he go to the hospital for an examination. But they may already have entered the dominant diabetic nephropathy (overtDN).

Blood test is the most common diagnosis method of the hospital currently. It takes ¥48 to test the blood β2-microglobulin. However, Dr.Liu said that if a portable urine test method can be developed, it can not only alleviate the pain of blood drawing, but also greatly improve the awareness of diabetes patients and the rate of early visits.

In this interview we exchanged ideas with doctors, and we have learned that from a clinical perspective, our project is more suitable for use at home. It can greatly arouse the awareness of early patients, which can indirectly improve the diagnosis rate and provide the best time for treatment.

Fig.2 Interviews with doctors

Interview with the researches in the Dalian Institute of Chemical Physics(DICP)

In order to better understand the current situation of urine testing, the team members came to the Research Group of Biomolecular Efficient Separation and Characterization of Dalian Institute of Chemical Physics, Chinese Academy of Sciences in October 2018. We exchanged ideas with researcher Yuan Huiming. Researcher Yuan said that the main problem in urine testing is to eliminate interference from other proteins in the urine. The nanobody of β2-microglobulin we selected is more specific and can solve this problem well. On the other hand, our liquid crystal detection method has extremely high sensitivity and has great advantages for the detection of trace proteins in urine.

This exchange allowed us to see the achievability and practical application of our project from the aspect of technical application. It also let us have confidence in our projects.

Fig.3 Interview with the researches