Difference between revisions of "Team:BIT"

 
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                <p id="big-title">JACOB 2.0</p>
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                <p id="small-title">Just A Creative assay for detection Of Biomarkers</p>
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                <h2>BIT-dedication makes perfection.</h2>
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                <p>We, team BIT, are constantly seeking to revolutionize diagnosis through synthetic biology and engineering. Since 2015 our first show at iGEM, we had already built 4 prototypes that attacked pressing issues in unique angles, including ‘breast cancer detection’ and 'Disease Alarm'. Most importantly, we revisit each project to maximize its performance and further its influence. Last year we brought the project JACOB, an integrated biosensor of bacteria engineering, aptamer, and microfluidic technology. Today we present you JACOB 2.0, a new-gen diagnostic device with major upgrades. Come and take a look!</p>
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                    <a class="one-own" href="https://2018.igem.org/Team:BIT/Bio/Overview">
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                        <p>Bio</p>
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                        <p>Model</p>
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                        <p>Hardware</p>
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<h1> Preliminary project description </h1>
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                        <p>Practice</p>
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                        <p>Team</p>
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                    <a class="one-own" href="https://2018.igem.org/Team:BIT/Medal">
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                        <p>Medal</p>
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Based on the demand of the market and the background, In this project, we design an artificial biological system used for early warning detection a particular biomarkers , we try to use biosensors which will help the cancer screening process become more convenient . Even the LOD(limit of detection) is limited. We will try our best to improve accuracy of this system.
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The specific method is: to detect the content of specific cancer markers in blood samples by directed engineered bacteria system. Use specific small molecules to replace protein biomarkers’,mostly are macromolecules incoming signal as signal conversion process. After that,small molecules will get into the engineering bacteria, then the bacteria can produce green fluorescent protein through a series of operations.Use microfluidic chip device to load the biological component. And hardware in this system is used to detect the fluorescence signal. After establishing the equivalence relation between fluorescence and biomarkers, biomarkers content in blood will be calculated, and the probability of patients' disease can be deduced. Users can go to the hospital for more accurate detection after receiving early warning information . This is important to the early discovery of the disease in the public, which can reduce the deterioration of the disease due to the lack and late of detection.
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Latest revision as of 03:16, 18 October 2018

<!DOCTYPE html> Home

JACOB 2.0

Just A Creative assay for detection Of Biomarkers

BIT-dedication makes perfection.

We, team BIT, are constantly seeking to revolutionize diagnosis through synthetic biology and engineering. Since 2015 our first show at iGEM, we had already built 4 prototypes that attacked pressing issues in unique angles, including ‘breast cancer detection’ and 'Disease Alarm'. Most importantly, we revisit each project to maximize its performance and further its influence. Last year we brought the project JACOB, an integrated biosensor of bacteria engineering, aptamer, and microfluidic technology. Today we present you JACOB 2.0, a new-gen diagnostic device with major upgrades. Come and take a look!

Bio

Model

Hardware

Practice

Team

Medal