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| | | |
| </section> | | </section> |
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| <h2 class="inner-h">Software</h2> | | <h2 class="inner-h">Software</h2> |
| </header> | | </header> |
| + | |
| + | <section> |
| + | <h3 class="inner-h">Introduction</h3> |
| + | <p class="inner-text"> |
| + | Although the calcium leakage plays a notable role in the development of Heart Failure (HF), it is hard to detect with noninvasive methods in clinical practice. The severity of HF can also be estimated by the level of calcium leakage, which in turn helps the clinical investors to determine the dosage and methodology of AAV based gene therapy. Therefore, we invented a software which can adopt the BNP expression level in patients' blood to reckon the level of calcium leakage, to choose of different AAVs and the to discriminate of expressing promoters. |
| + | </p> |
| + | </section> |
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| <section> | | <section> |
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| </p> | | </p> |
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− | <center><img src="https://static.igem.org/mediawiki/2018/5/5e/T--SMMU-China--b1.png"></center> | + | <center><img src="https://static.igem.org/mediawiki/2018/5/5e/T--SMMU-China--b1.png" width="800px"></center> |
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− | <center><img src="https://static.igem.org/mediawiki/2018/5/58/T--SMMU-China--b2.png"></center> | + | <center><img src="https://static.igem.org/mediawiki/2018/5/58/T--SMMU-China--b2.png" width="600px"></center> |
| | | |
| <h5 class="inner-h">2. Treatment plan assisting module</h5> | | <h5 class="inner-h">2. Treatment plan assisting module</h5> |
| | | |
| <p class="inner-text"> | | <p class="inner-text"> |
− | a) Input: select the target value of reducing calcium leakage; | + | a)Input: select the target value of reducing calcium leakage; |
| <br> | | <br> |
− | b) output: based on your combination of virus serotype, promoter, and serum BNP value to calculate the titer of the therapeutic virus required for treatment and second injection time. | + | b)Output: based on your combination of virus serotype, promoter, and serum BNP value to calculate the titer of the therapeutic virus required for treatment. |
| | | |
| </p> | | </p> |
| | | |
− | <center><img src="https://static.igem.org/mediawiki/2018/f/f9/T--SMMU-China--b3.png"></center> | + | <center><img src="https://static.igem.org/mediawiki/2018/f/f9/T--SMMU-China--b3.png" width="600px"></center> |
| | | |
| <h5 class="inner-h">3. The custom setting assessment module </h5> | | <h5 class="inner-h">3. The custom setting assessment module </h5> |
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| c) Output: the expectation of calcium leakage reduction. | | c) Output: the expectation of calcium leakage reduction. |
| </p> | | </p> |
| + | |
| + | <center><img src="https://static.igem.org/mediawiki/2018/2/2d/T--SMMU-China--b4.png" width="600px"></center> |
| | | |
| <h3 class="inner-h">Github</h3> | | <h3 class="inner-h">Github</h3> |
| + | |
| + | <p class="inner-text"> |
| + | You can download and use our software from <a href=" https://github.com/igemsoftware2018/Team_SMMU_China">Github</a>. |
| + | </p> |
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