Difference between revisions of "Team:EPFL"

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    <h1>CAPOEIRA</h1>
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    <img src="https://static.igem.org/mediawiki/2018/3/3e/T--EPFL--encapsulin.jpg" class="img-circle" alt="encapsulin" width="150" height="150">
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    <h3>Cancer Personalized Encapsulin Immunotherapy and Relapse Assay</h3>
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      <a href="https://2018.igem.org/Team:EPFL/Description"><h2>What is CAPOEIRA ?</h2></a>
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                                    <h2 class="text-white my-4">
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      <p style="font-size:20px;">While cancer is still the disease of the 21st century, new insights and approaches are changing the landscape of cancer therapy. Cancer immunotherapy is becoming a key technique for the successful fight against cancer. The goal of cancer immunotherapy
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                      <span class="display-4 font-weight-bold">CAPOEIRA</span>
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        is to harness the immune system in the fight against cancer. The project that the EPFL 2018 iGEM team is presenting is focused on the development of a new therapeutic approach to target specific types of cancer using immunotherapy methods, with
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                    </h2>
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        a focus on vaccines. Furthermore, the project aims to integrate the personalized medicine approaches, by using patient-specific neoantigens to trigger the immune system and produce the response against cancer. The project is exhaustive and can
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                                    <p class="lead text-white">Cancer Personalized Encapsulin Immunotherapy and Relapse Assay</p>
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        be divided into the following parts:</p>
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      <br>
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                                            <span class="btn-inner--text">Learn more about our project</span>
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                        </div>
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            <h3>Detection of cancer patient specific tumor mutations and neoantigens</h3>
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            <a href="#sct_page_examples" class="tongue tongue-bottom scroll-me"><i class="fas fa-angle-down"></i></a>
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          <img src="https://static.igem.org/mediawiki/2018/9/93/T--EPFL--vaccine.png" alt="vaccine">
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                    <h3 class="heading h3">What is CAPOEIRA ?</h3>
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                    <div class="text-center mt-4">
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            <h3>Expression of the neoantigens and the adjuvant using encapsulin</h3>
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                        <p class="lead lh-180">While cancer is still the disease of the 21st century, new insights and approaches are changing the landscape of cancer therapy. Cancer immunotherapy is becoming a key technique for the successful fight against cancer. The goal of cancer immunotherapy is to harness the immune system in the fight against cancer. The project that the EPFL 2018 iGEM team is presenting is focused on the development of a new therapeutic approach to target specific types of cancer using immunotherapy methods, with a focus on vaccines. Furthermore, the project aims to integrate the personalized medicine approaches, by using patient-specific neoantigens to trigger the immune system and produce the response against cancer. The project is exhaustive and can be divided into the following parts:</p>
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            <h3>Maturation of dendritic cells and T-cells</h3>
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                                        <h3 class="h5">Detection</h3>
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                                        <p>Detection of cancer patient specific tumor mutations and neoantigens</p>
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          <img src="https://static.igem.org/mediawiki/2018/3/3c/T--EPFL--follow_up.png" alt="follow_up">
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            <h3>Detection of cancer relapse using liquid biopsies of ctDNA and cancer miRNA</h3>
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                                        <h3 class="h5">Vaccine</h3>
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                                        <p>Expression of the neoantigens and the adjuvant using encapsulin</p>
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                                        <h3 class="h5">Immune response</h3>
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                                        <p>Maturation of dendritic cells and T-cells</p>
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                                    </div>
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                                        <h3 class="h5">Follow up</h3>
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                                        <p>Detection of cancer relapse using liquid biopsies of ctDNA and cancer miRNA</p>
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                                    </div>
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    </main>
 
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Revision as of 12:39, 23 August 2018

iGEM EPFL 2018 iGEM EPFL 2018

CAPOEIRA

Cancer Personalized Encapsulin Immunotherapy and Relapse Assay

Learn more about our project

What is CAPOEIRA ?

While cancer is still the disease of the 21st century, new insights and approaches are changing the landscape of cancer therapy. Cancer immunotherapy is becoming a key technique for the successful fight against cancer. The goal of cancer immunotherapy is to harness the immune system in the fight against cancer. The project that the EPFL 2018 iGEM team is presenting is focused on the development of a new therapeutic approach to target specific types of cancer using immunotherapy methods, with a focus on vaccines. Furthermore, the project aims to integrate the personalized medicine approaches, by using patient-specific neoantigens to trigger the immune system and produce the response against cancer. The project is exhaustive and can be divided into the following parts:

Detection

Detection of cancer patient specific tumor mutations and neoantigens

Vaccine

Expression of the neoantigens and the adjuvant using encapsulin

Immune response

Maturation of dendritic cells and T-cells

Follow up

Detection of cancer relapse using liquid biopsies of ctDNA and cancer miRNA