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<p>This page is used by the judges to evaluate your team for the <a href="https://2018.igem.org/Judging/Medals">medal criterion</a> or <a href="https://2018.igem.org/Judging/Awards"> award listed below</a>. </p>
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<p> Delete this box in order to be evaluated for this medal criterion and/or award. See more information at <a href="https://2018.igem.org/Judging/Pages_for_Awards"> Instructions for Pages for awards</a>.</p>
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<h1>Human Practices</h1>
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At iGEM we believe societal considerations should be upfront and integrated throughout the design and execution of synthetic biology projects. “Human Practices” refers to iGEM teams’ efforts to actively consider how the world affects their work and the work affects the world. Through your Human Practices activities, your team should demonstrate how you have thought carefully and creatively about whether your project is responsible and good for the world. We invite you to explore issues relating (but not limited) to the ethics, safety, security, and sustainability of your project, and to show how this exploration feeds back into your project purpose, design and execution.
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<h1>Overview</h1>
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<p>When considering how to develop our Candida albican detection assay into a more user friendly test, we consulted with several professionals to gain insight and conducted an Institutional Review Board (IRB) survey that provided feedback from potential users. Our process for Human Practices consisted of six basic steps.</p>
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<p>For more information, please see the <a href="https://2018.igem.org/Human_Practices">Human Practices Hub</a>. There you will find:</p>
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<h1 style="margin-bottom:0;">Step 1</h1>
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<h2 style="text-align: center;margin-top:0;">Doing research on the problem and learning diagnosis and treatment processes</h2>
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<li> an <a href="https://2018.igem.org/Human_Practices/Introduction">introduction</a> to Human Practices at iGEM </li>
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<p>Learning about how current tests are being used and what doctors would prefer to have was important in transforming our assay. We wanted to make sure that our diagnosis test could benefit professionals working.</p>
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<li>tips on <a href="https://2018.igem.org/Human_Practices/How_to_Succeed">how to succeed</a> including explanations of judging criteria and advice about how to conduct and document your Human Practices work</li>
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<li>descriptions of <a href="https://2018.igem.org/Human_Practices/Examples">exemplary work</a> to inspire you</li>
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<li>links to helpful <a href="https://2018.igem.org/Human_Practices/Resources">resources</a></li>
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<li>And more! </li>
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<p>Who we talked to:</p>
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<p>On this page, your team should document all of your Human Practices work and activities. You should write about the Human Practices topics you considered in your project, document any activities you conducted to explore these topics (such as engaging with experts and stakeholders), describe why you took a particular approach (including referencing any work you built upon), and explain if and how you integrated takeaways from your Human Practices work back into your project purpose, design and/or execution. </p>
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<p>If your team has gone above and beyond in work related to safety, then you should document this work on your Safety wiki page and provide a description and link on this page. If your team has developed education and public engagement efforts that go beyond a focus on your particular project, and for which would like to nominate your team for the Best Education and Public Engagement Special Prize, you should document this work on your Education and Education wiki page and provide a description and link here. </p>
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<h3 style="margin-top:0;">Practicing OBGYN: Dr. Lisa Yang</h3>
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<p>Dr. Lisa Yang is a practicing OBGYN, who regularly sees patients, performs surgeries, and works at the hospital with labor and delivering babies. She also works with residents in training by overseeing the work they do with different tests they conduct and surgeries they perform. She answered our questions on different diagnostic tests that she conducts, which is located on the problem page.</p>
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<p>From our talk with her we learned what her ideal detection method would encompass:</p>
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<p>The iGEM judges will review this page to assess whether you have met the Silver and/or Gold medal requirements based on the Integrated Human Practices criteria listed below. If you nominate your team for the <a href="https://2018.igem.org/Judging/Awards">Best Integrated Human Practices Special Prize</a> by filling out the corresponding field in the <a href="https://2018.igem.org/Judging/Judging_Form">judging form</a>, the judges will also review this page to consider your team for that prize.
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<li>If she is able to get information while in office and not have to send things into the lab</li>
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<li>If the test has a good positive predictive value and a low negative predictive value  ie. accuracy</li>
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<li>If the test is relatively cost effective</li>
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<li>If her staff is able to perform the test because she either has to conduct the test herself or send it into a lab</li>
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<li>If the test is comparable to the gold standard test and can deliver the same results</li>
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<h3>Silver Medal Criterion #3</h3>
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<p>Convince the judges you have thought carefully and creatively about whether your work is responsible and good for the world. Document how you have investigated these issues and engaged with your relevant communities, why you chose this approach, and what you have learned. Please note that surveys will not fulfill this criteria unless you follow scientifically valid methods. </p>
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<h3>Gold Medal Criterion #1</h3>
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<p>Expand on your silver medal activity by demonstrating how you have integrated the investigated issues into the purpose, design and/or execution of your project. Document how your project has changed based upon your human practices work.
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<h1 style="margin-bottom:0;">Step 2</h1>
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<h2 style="text-align: center;margin-top:0;">Developing our Paper-Based Assay</h2>
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<p>Throughout the process of building our paper-based assay, we consulted professionals who helped us change our assay to better fit the needs of healthcare professionals and patients everywhere.</p>
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<p>Who we talked to:</p>
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<h3>Best Integrated Human Practices Special Prize</h3>
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<p>To compete for the Best Integrated Human Practices prize, please describe your work on this page and also fill out the description on the judging form. </p>
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<p>How does your project affect society and how does society influence the direction of your project? How might ethical considerations and stakeholder input guide your project purpose and design and the experiments you conduct in the lab? How does this feedback enter into the process of your work all through the iGEM competition? Document a thoughtful and creative approach to exploring these questions and how your project evolved in the process to compete for this award!</p>
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<p>You must also delete the message box on the top of this page to be eligible for this prize.</p>
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<h3 style="margin-top:0;">Dr. Linnes</h3>
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<p>Dr. Linnes is an assistant professor at Purdue University who specializes in developing paper-based assays. She provided examples of paper-based assays she designed and brought to light different factors to include within our assay. Throughout the improvement of our assay, she was able to provide input and expertise in the design.</p>
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<h1 style="margin-bottom:0;">Step 3</h1>
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<h2 style="text-align: center;margin-top:0;">Learn how to Relay our research to the public</h2>
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<p>Communicating our research and transporting or assay to the public is important when making our assay more globally accessible. </p>
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<p>Who we talked to:</p>
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<h3 style="margin-top:0;">Dr. Cooky</h3>
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<p>Dr. Cooky is an associate professor of American Studies and Women’s, Gender, and Sexuality Studies at Purdue University. During our project she helped us in focusing in on how we can help the general public understand our research. She also brought to light that yeast infections are “a relatively minor medical issue that creates a disproportionate impact on women’s lives.”</p>
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<p>Throughout our talk with her she brought to our attention:</p>
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<li>How the youth is getting educated on sexual health and what their programs entail</li>
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<li>Whether or not sexual health education programs are teach about infections like vulvovaginal candidiasis</li>
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<li>Different misconceptions that surround women’s health and the implications of what going to get treatment for infections like vulvovaginal candidiasis entail</li>
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<li>How different cultures view women’s health and the challenges women face in obtaining a test and getting treatment</li>
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<li>Make sure our test is something women could do by themselves by keeping it simple and accessible</li>
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<li>Consider a global reach with our test</li>
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<p>Dr. Clase is the director of the Biotechnology Innovation and Regulatory Science Center and also a professor in Agricultural and Biological Engineering as well as Technology Leadership and Innovation. She works extensively with building programs to help secure access to medicine in Africa and developing nations. Dr. Clase helped us by answering questions about bringing our assay to the global market. From talking with her she answered our questions about international healthcare and suggested we find out how people learn about healthcare and where people go if there is no doctor or nurse.</p>
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<h1 style="margin-bottom:0;">Step 4</h1>
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<h2 style="text-align: center;margin-top:0;">Changing our detection method based on the conversations with professionals</h2>
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<p>Originally we designed our assay with as many steps as necessary in order to gain the best results with the least amount of factors to account for. However, based on our talk Dr. Linnes who shed light on a method of a three step application system that users prefer. Due to this discovery, we modified our assay to fit within the three step application suggestion.</p>
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<h2 style="text-align: center;margin-top:0;">Assess public knowledge through survey</h2>
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<p>A major part of our research was finding a way to make the assay more user-friendly than current brands. In order to do so we conducted an IRB survey that used Amazon Mechanical Turk that helped us receive feedback from a diverse demographic range.</p>
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<div class="myButton medium" href="https://2018.igem.org/Team:Purdue/Quiz" style="width:370px;">Click here to learn more</div>
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<h2 style="text-align: center;margin-top:0;">Public Engagement</h2>
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<p>We had the opportunity to work with Purdue University Libraries in creating an event called DIYBio and Maker, where we educated the Purdue community about synthetic biology and our project. During the event we interacted with students and shed light on the importance of synthetic biology and the implications of our research.</p>
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<p>A major part of our research was finding a way to make the assay more user-friendly than current brands. In order to do so we conducted an IRB survey that used Amazon Mechanical Turk that helped us receive feedback from a diverse demographic range.</p>
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<div class="myButton medium" href="https://2018.igem.org/Team:Purdue/Quiz" style="width:370px;">Click Here to lean more</div>
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Revision as of 19:30, 14 October 2018

Bootstrap Example

Human Practices

Overview

When considering how to develop our Candida albican detection assay into a more user friendly test, we consulted with several professionals to gain insight and conducted an Institutional Review Board (IRB) survey that provided feedback from potential users. Our process for Human Practices consisted of six basic steps.

Step 1

Doing research on the problem and learning diagnosis and treatment processes

Learning about how current tests are being used and what doctors would prefer to have was important in transforming our assay. We wanted to make sure that our diagnosis test could benefit professionals working.

Who we talked to:

Step 2

Developing our Paper-Based Assay

Throughout the process of building our paper-based assay, we consulted professionals who helped us change our assay to better fit the needs of healthcare professionals and patients everywhere.

Who we talked to:

Step 3

Learn how to Relay our research to the public

Communicating our research and transporting or assay to the public is important when making our assay more globally accessible.

Who we talked to:

Integrated HP:

Step 4

Changing our detection method based on the conversations with professionals

Originally we designed our assay with as many steps as necessary in order to gain the best results with the least amount of factors to account for. However, based on our talk Dr. Linnes who shed light on a method of a three step application system that users prefer. Due to this discovery, we modified our assay to fit within the three step application suggestion.

Step 5

Assess public knowledge through survey

A major part of our research was finding a way to make the assay more user-friendly than current brands. In order to do so we conducted an IRB survey that used Amazon Mechanical Turk that helped us receive feedback from a diverse demographic range.

Click here to learn more

Step 6

Public Engagement

We had the opportunity to work with Purdue University Libraries in creating an event called DIYBio and Maker, where we educated the Purdue community about synthetic biology and our project. During the event we interacted with students and shed light on the importance of synthetic biology and the implications of our research.

Collaboration

A major part of our research was finding a way to make the assay more user-friendly than current brands. In order to do so we conducted an IRB survey that used Amazon Mechanical Turk that helped us receive feedback from a diverse demographic range.

Click Here to lean more

Special Thanks

to all those that made this possible

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Contact Us

igem@purdue.edu

Kevin Fitzgerald, B025

1203 W State St.

West Lafayette, IN 47906