Difference between revisions of "Team:Oxford/InitialIdeas"

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<tr><th>Idea</th><th>Track</th><th>Benefits</th><th>Limitations</th></tr>
 
<tr><th>Idea</th><th>Track</th><th>Benefits</th><th>Limitations</th></tr>
<tr><td><B>Biodegradation</B>  - Removal of nitrates from water systems to reduce effects of eutrophication</td><td>Environment</td><td>High demand for environmental projects, Potential to use framework for broad water purification applications</td><td>Biological containment issues, Availability of chassis may limit scope of experimental data</td></tr>
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<tr><td><B>Biodegradation</B>  - Removal of nitrates from water systems to reduce effects of eutrophication</td><td>Environment</td><td></p>High demand for environmental projects</p>
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</p>Potential to use framework for broad water purification applications</p></td><td></p>Biological containment issues</p>
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</p>Availability of chassis may limit scope of experimental data</p></td></tr>
 
<tr><td><B>Snake Bites</B>  - Using protease composition to distinguish between different venoms</td><td>Diagnostics</td><td>Large impact in developing countries, High accuracy of protease detection</td><td>Hard to improve upon previous projects, Difficult to create cell-free device</td></tr>
 
<tr><td><B>Snake Bites</B>  - Using protease composition to distinguish between different venoms</td><td>Diagnostics</td><td>Large impact in developing countries, High accuracy of protease detection</td><td>Hard to improve upon previous projects, Difficult to create cell-free device</td></tr>
 
<tr><td><B>Latex Allergy</B>  - Designing a filter with an agent to bind/degrade the putative latex allergen hevein</td><td>Therapeutics</td><td>No current treatments focus on preventing latex exposure due to allergen molecule size, Possible application for other airborne allergens</td><td>Very small population affected, Lack of existing research: unclear if allergen cleavage reduces the response</td></tr>  
 
<tr><td><B>Latex Allergy</B>  - Designing a filter with an agent to bind/degrade the putative latex allergen hevein</td><td>Therapeutics</td><td>No current treatments focus on preventing latex exposure due to allergen molecule size, Possible application for other airborne allergens</td><td>Very small population affected, Lack of existing research: unclear if allergen cleavage reduces the response</td></tr>  

Revision as of 22:26, 14 October 2018

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Initial Ideas

Prior to our initial survey, we had many different ideas for potential projects:

IdeaTrackBenefitsLimitations
Biodegradation - Removal of nitrates from water systems to reduce effects of eutrophicationEnvironment

High demand for environmental projects

Potential to use framework for broad water purification applications

Biological containment issues

Availability of chassis may limit scope of experimental data

Snake Bites - Using protease composition to distinguish between different venomsDiagnosticsLarge impact in developing countries, High accuracy of protease detectionHard to improve upon previous projects, Difficult to create cell-free device
Latex Allergy - Designing a filter with an agent to bind/degrade the putative latex allergen heveinTherapeuticsNo current treatments focus on preventing latex exposure due to allergen molecule size, Possible application for other airborne allergensVery small population affected, Lack of existing research: unclear if allergen cleavage reduces the response
Date Rape Drug Sensor - Designing a cell-free biosensor for the detection of benzodiazepines in drinksEnvironmentImportant real world issue, Potential to build upon successful previous projects e.g. E.ChromiDifficult to justify extent of improvement from previous work, Limits to sensitivity of detection
Biofertiliser - Engineering nitrogen fixation pathways in non-leguminous plantsFood and NutritionPotential to be adapted for widespread issues such as desertificationDifficult to predict efficacy of system in plant models, Biological containment issues
Flavivirus Detection - Distinguishing between different mosquito-borne infections via protein detectionDiagnosticsHigh morbidity in developing countries, Non-specific nature of symptoms often delays treatment onsetSimilar devices have recently been developed, Difficult to improve upon existing diagnostics within given time frame

Three ideas were subsequently shortlisted: