Difference between revisions of "Team:MIT/Public Engagement"

The course was developed as a result of the iGEM MIT team delving into iGEM Human Practices literature and realizing that currently used synthetic biology curriculums do not include enough about the impact of research and technological advancements on society. To remove public mistrust of new synthetic advancements, it's very important to cultivate an environment that promotes responsible research within the scientific community.

The curriculum developed by team MIT is meant to be an optional addition to synthetic biology courses that already exist (such as the BioBuilder Club). It does not hope to replace these courses, but rather augment them by providing a fuller picture of synthetic biology and its intersections with the real world. The course consists of 4 one-hour modules following the AREA guidelines: Anticipate, Reflect, Engage, and Act. These guidelines were followed by team MIT in our own scientific endeavours and we hoped that by formalizing our method into a curriculum, we could teach and encourage other young researchers to develop responsive research habits and therefore create a culture of responsive and transparent science.

Each module in our curriculum consists of a lecture section, an individual activity section and a group activity section. The short lecture sections will involve dissemination of information that will teach students the Responsible Research and Innovation (RRI) framework: how to anticipate potential opportunities of a research project, what considerations must be reflected upon before diving into commercialization of a product, how to engage with the public and relevant stakeholders in order to gain a deeper insight into the impact of the technology, and finally how can we, as researchers, scientists, teachers and policymakers, act appropriately in order to ensure that research is done responsibly.

The individual activity sections will vary from reading case studies and filling out Stakeholder/Value matrices to writing policy drafts as policymakers in order to amend laws regulating biotechnology and synthetic biology.

The group activity sections will range from group discussions for carrying out SWOT (Strengths, Weaknesses, Opportunities, Threats) analysis to role-playing a possible dialogue/engagement between a researcher and a stakeholder affected by the researcher's technology.

The course aims to foster a habit of healthy discourse in students and emphasizes critical thinking as a major tool to navigate the political, ethical, economic, and societal implications of all our actions.

BioBuilder Club is a program that "engages high school teams around the world who use synthetic biology to develop novel biotechnologies." We reached out to the founder of the program, Natalie Kuldell and she offered to let us teach an upcoming delegation from Wuhan University, China. We developed a one-hour crash course for this delegation in order to gauge how responsive the students were to our interactive responsible science curriculum.

HSSP is multi-weekend program held once during the spring and once during the summer at MIT, open to rising 7th graders to current 12th graders. We taught a group of about 80-100 students during the last week of July. We developed a 90-minute lesson-plan that included a quick intro to synthetic biology, some examples of synthetic tools used and an ethical science segment where we divided the students into groups in order to lead discussions about how some new upcoming controversial synthetic solutions were considered ethically problematic and what could be done to make them more acceptable by the public.

Similarly, we taught this crash-course to students from the BoSTEM scholars program. The MIT BoSTEM Scholars Academy addresses issues related to STEM education access and targets students who will increase diversity in those fields. The program aims to provide Greater Boston area high school students, the majority of which are women and underrepresented minorities, with the opportunity to gain an experience in STEM. Team MIT was really eager to collaborate with their program, so that we could inspire more interest in the young kids who joined us for the crash-course as well as a lab tour.

Team MIT reached out to MIT Museum so that we could present our project to the general public. We wanted to reach out to a varied population, which included young kids, tourists and general science enthusiasts and normalize the idea of syn-bio therapeutics such as our treatment for dental caries. Our project was interactive and avoided using too much biology jargon so that the information we were trying to impart was easily accessible to all.

To demonstrate how biofilm form on teeth, we used magnets and iron filings. We illustrated how one bacterial cell could attract other bacteria around it and how this signalling and attraction lead to all of them accumulating on our teeth and forming biofilm!

To demonstrate how biological circuits worked in synthetic biology, we used an actual circuit, where we represented different parts of the circuit by different biological parts. We illustrated how we had transplanted a signalling system from a bacterial cell into a mammalian cell and how that transplantation leads to the turning on of an LED light (which represented our output protein that prevents biofilm formation).

The MIT Museum demonstration was on overall success and we managed to interact with people of different ages and from different parts of the world. We also added an "Ask a Synthetic Biologist Anything" booth so if people had extra questions after our demo could learn even more. We felt that this was very essential to breaking down incorrect myths people believed about synthetic biology.

Here are the posters we created for this exhibit. Feel free to use them to host conversations about synthetic biology within your own communities!