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Revision as of 19:13, 7 August 2018

description01 Can Cells be Controlled with Sound? Today, it is routine to induce the expression of a gene in E. coli using only a small molecule. Real small. Think arabinose, lactose, and rhamnose. Pouring through previous research, we’ve determined that directed soundwaves can stress a cell’s pumps to open. Large enough for our ‘expression inducing’ molecules to pass inside the cell‘s walls. One may ask, can sound become a routine means to induce gene expression in engineered E. coli? While Slovenia’s Sonicell and SUS Tech’s Cearll’s Secret projects pursued a similar question in mammalian cells. We focused on inducing E. coli to express chromogenic reporters.. In other words, we’ve caused targeted cells to change colors by beaming sound at them. Today, it is routine to induce the expression of a gene in E. coli using only a small molecule. Real small. Think arabinose, lactose, and rhamnose. Pouring through previous research, we’ve determined that directed soundwaves can stress a cell’s pumps to open. Large enough for our ‘expression inducing’ molecules to pass inside the cell‘s walls. One may ask, can sound become a routine means to induce gene expression in engineered E. coli? While Slovenia’s Sonicell and SUS Tech’s Cearll’s Secret projects pursued a similar question in mammalian cells, we’re studying the details of both projects to induce chromogenesis in engineered E.Coli cells. In English, we’ve caused targeted cells to change colors by beaming sound at them.

Description

Tell us about your project, describe what moves you and why this is something important for your team.

What should this page contain?

  • A clear and concise description of your project.
  • A detailed explanation of why your team chose to work on this particular project.
  • References and sources to document your research.
  • Use illustrations and other visual resources to explain your project.

Inspiration

See how other teams have described and presented their projects:

Advice on writing your Project Description

We encourage you to put up a lot of information and content on your wiki, but we also encourage you to include summaries as much as possible. If you think of the sections in your project description as the sections in a publication, you should try to be concise, accurate, and unambiguous in your achievements.

References

iGEM teams are encouraged to record references you use during the course of your research. They should be posted somewhere on your wiki so that judges and other visitors can see how you thought about your project and what works inspired you.