Difference between revisions of "Team:New York City"
| Line 15: | Line 15: | ||
border-radius: 15px; | border-radius: 15px; | ||
} | } | ||
| + | |||
</style> | </style> | ||
</head> | </head> | ||
<body> | <body> | ||
<div class="container"> | <div class="container"> | ||
| − | <nav class=" | + | <nav class="sticky-top py-3 navbar navbar-expand-lg navbar-light mr-auto"> |
<div class="container d-flex flex-column flex-md-row justify-content-between"> | <div class="container d-flex flex-column flex-md-row justify-content-between"> | ||
<div class="navbar-brand"><a href="#">HD Resolution</a></div> | <div class="navbar-brand"><a href="#">HD Resolution</a></div> | ||
| Line 29: | Line 30: | ||
</a> | </a> | ||
<div class="dropdown-menu" aria-labelledby="navbarPR"> | <div class="dropdown-menu" aria-labelledby="navbarPR"> | ||
| − | <a class="dropdown-item" href=" | + | <a class="dropdown-item" href="#">What is HD?</a> |
| − | <a class="dropdown-item" href=" | + | <a class="dropdown-item" href="">Coming Soon</a> |
</div> | </div> | ||
</li> | </li> | ||
| Line 38: | Line 39: | ||
</a> | </a> | ||
<div class="dropdown-menu" aria-labelledby="navbarNB"> | <div class="dropdown-menu" aria-labelledby="navbarNB"> | ||
| − | <a class="dropdown-item" href=" | + | <a class="dropdown-item" href="">Coming Soon</a> |
</div> | </div> | ||
</li> | </li> | ||
| Line 46: | Line 47: | ||
</a> | </a> | ||
<div class="dropdown-menu" aria-labelledby="navbarHP"> | <div class="dropdown-menu" aria-labelledby="navbarHP"> | ||
| − | <a class="dropdown-item" href=" | + | <a class="dropdown-item" href="">Coming Soon</a> |
</div> | </div> | ||
</li> | </li> | ||
| Line 60: | Line 61: | ||
<div class="container text-center" align="center"> | <div class="container text-center" align="center"> | ||
<div class="row"> | <div class="row"> | ||
| − | <div class="col-sm- | + | <div class="col-sm-12" align="center"> |
| − | <h1 >Using genomics for a <span class="shiny">Resolution</span> to Huntington's Disease (<span class="shiny">HD</span>)</h1> | + | <h1 >Using genomics for a <span class="shiny">Resolution</span> to <br/> Huntington's Disease (<span class="shiny">HD</span>)</h1> |
</div> | </div> | ||
| − | <div class="col-sm- | + | </div> |
| + | <div class="row"> | ||
| + | <div class="col-sm-12" align="center"> | ||
<img class="headimage" src="https://static.igem.org/mediawiki/2018/1/1c/T--New_York_City--logo.PNG" width=100%/> | <img class="headimage" src="https://static.igem.org/mediawiki/2018/1/1c/T--New_York_City--logo.PNG" width=100%/> | ||
</div> | </div> | ||
Revision as of 06:48, 31 August 2018
Using genomics for a Resolution to
Huntington's Disease (HD)
WHAT
Huntington's Disease (HD) is a genetic disorder that results in the breakdown of nerve cells in the brain. Although the disease affects the whole brain, the basal ganglia, which plays a critical role in motor functions and behavior, is most severely affected. Thus, symptoms of HD include involuntary movements, personality changes, and cognitive problems. Over time, the effects of HD is extremely debilitating, eventually rendering a patient unable to speak, walk, or even reason.
WHY
HD is a result of a specific mutation in the huntingtin (HTT) gene, which results in a faulty production of the HTT protein, mHTT. The mutation is a trinucleotide repeat of the codon CAG, where 40 or more will lead to the expression of HD.
WHO
The most common form of HD is adult-onset, affecting people between their 30s and 40s. Many people form families and have children by the time they are diagnosed with HD, which automatically gives their children a 50% chance of inheriting the disease. HD affects about 1 in every 10,000 people worldwide.
HOW
Our goal is to develop a cure to Huntington's Disease by employing RNA strand displacement technology to target erroneous mRNA within the affected cells and replace it with the corrected RNA strand for proper protein synthesis.