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<p>Biocatalysis is the use of enzymes in chemical synthesis, and it has expanded significantly over the last few decades due to <b>shorter synthesis routes</b>, <b>reduced waste</b> and <b>high product yields</b> in comparison to chemical synthesis methods. Yet, each unique enzyme takes years to develop, while the demand for biocatalysts is growing at a rapid pace.</p> | <p>Biocatalysis is the use of enzymes in chemical synthesis, and it has expanded significantly over the last few decades due to <b>shorter synthesis routes</b>, <b>reduced waste</b> and <b>high product yields</b> in comparison to chemical synthesis methods. Yet, each unique enzyme takes years to develop, while the demand for biocatalysts is growing at a rapid pace.</p> |
Revision as of 11:29, 17 September 2018
Vilnius-Lithuania Overgraduate!
Biocatalysis is the use of enzymes in chemical synthesis, and it has expanded significantly over the last few decades due to shorter synthesis routes, reduced waste and high product yields in comparison to chemical synthesis methods. Yet, each unique enzyme takes years to develop, while the demand for biocatalysts is growing at a rapid pace.
The field of enzyme engineering is still in its youth, because of the great complexity of the particular field. From numerous amino acid combinations that form enzymes, only a handful can transform a given substrate into the required product. After pharmaceutical company fully develops a particular drug, it takes an average of two additional years to develop the enzyme(s) that can facilitate synthesis of such molecule. Enzyme engineering leaves a lot to be desired, even with the state of art screening solutions and the rise of directed protein evolution.
One of the major limiting factors concerning biocatalyst engineering is the protein activity characterization speed. That is why our goal is to develop a new generation high-throughput enzyme screening method, which will allow to move from characterization of thousand mutants in a day to billions of mutants in an hour. A change of this scale matters – large amount of data will allow our AI algorithms to evolve into new horizons – including the swift generation of novel enzymatic reactions and multiple enzyme metabolic route optimization.
Before you start
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Styling your wiki
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Inspiration
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