Difference between revisions of "Team:Kyoto/Basic Parts"
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<p>For this year’s iGEM competition, we have chosen to submit Rev protein for the award of <a href="">iGEMers can export their RNA sequences containing an RRE to the cytoplasm if they express Rev protein simultaneously. </p> | <p>For this year’s iGEM competition, we have chosen to submit Rev protein for the award of <a href="">iGEMers can export their RNA sequences containing an RRE to the cytoplasm if they express Rev protein simultaneously. </p> | ||
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<h5>How Rev works</h5> | <h5>How Rev works</h5> | ||
Revision as of 15:01, 7 October 2018
Basic Part
Protein
For this year’s iGEM competition, we have chosen to submit Rev protein for the award of iGEMers can export their RNA sequences containing an RRE to the cytoplasm if they express Rev protein simultaneously.
How Rev works
Rev recruits CRM1, a principal nuclear export factor in cells which mediates export of cellular RNAs including snRNA and all 4 ribosomal RNAs to the cytoplasm.
Key advantage
Rev protein makes it possible to export complex RNA structures from the nucleus to the cytoplasm, which otherwise cannot be achieved effectively.