Difference between revisions of "Team:HZAU-China/Design"
ShuguangWang (Talk | contribs) |
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/* border:2px solid black */ | /* border:2px solid black */ | ||
/* background-color: #323643 */ | /* background-color: #323643 */ | ||
| + | } | ||
| + | |||
| + | .xie{ | ||
| + | font-style: italic; | ||
| + | } | ||
| + | |||
| + | .zhengwen p{ | ||
| + | text-align: justify !important; | ||
| + | font-family: Arial, Helvetica, sans-serif !important; | ||
| + | color: #484848; | ||
| + | font-size: 22px !important; | ||
| + | padding-right: 20px; | ||
| + | |||
} | } | ||
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color: black; | color: black; | ||
border-bottom: 3px solid black; | border-bottom: 3px solid black; | ||
| − | + | margin-bottom: 20px; | |
} | } | ||
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<!-- 正文 --> | <!-- 正文 --> | ||
<div class="zhengwen"> | <div class="zhengwen"> | ||
| − | |||
<div id="float01" class="cur"> | <div id="float01" class="cur"> | ||
| − | <div class="h1"> | + | <div class="h1"><span class="xie">sifA</span> knock out</div> |
| − | + | <p>SifA maintains the integrity of Salmonella-containing vacuole (SCV) where Salmonella survive and replicate1. The exsistence of SCV limits GSDMD-N275 releasing to cytoplasma. what else, growth of <span class="xie">ΔsifA</span> mutant is inhibited in macrophage2.Thus, we knock out the sifA gene in order to prevent the stability of SCV and reduce the virulence of Salmonella. <span class="xie">ΔsifA</span> mutant was cnstructed by using gene editing systerm based on two-step allelic exchange3.</p> | |
</div> | </div> | ||
<div id="float02"> | <div id="float02"> | ||
| − | <div class="h1"> | + | <div class="h1">Targeting</div> |
</div> | </div> | ||
<div id="float03"> | <div id="float03"> | ||
| − | <div class="h1"> | + | <div class="h1">Regulation of pyroptosis</div> |
| + | </div> | ||
| + | <div id="float04"> | ||
| + | <div class="h1">Reference</div> | ||
</div> | </div> | ||
</div> | </div> | ||
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</div> | </div> | ||
<div class="floatCtro"> | <div class="floatCtro"> | ||
| − | <p class="daohanger"> | + | <p class="daohanger">sifA knock out</p> |
| − | <p class="daohanger"> | + | <p class="daohanger">Targeting</p> |
| − | <p class="daohanger"> | + | <p class="daohanger">Regulation of pyroptosis</p> |
| + | <p class="daohanger">Reference</p> | ||
<a> | <a> | ||
<span>Back to Top</span> | <span>Back to Top</span> | ||
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scrolls() | scrolls() | ||
function scrolls() { | function scrolls() { | ||
| − | var f1, f2, f3, bck; | + | var f1, f2, f3, f4, bck; |
var fixRight = $('div.floatCtro p'); | var fixRight = $('div.floatCtro p'); | ||
var blackTop = $('div.floatCtro a') | var blackTop = $('div.floatCtro a') | ||
| Line 729: | Line 745: | ||
f2 = $('#float02').offset().top; | f2 = $('#float02').offset().top; | ||
f3 = $('#float03').offset().top; | f3 = $('#float03').offset().top; | ||
| + | f4 = $('#float04').offset().top; | ||
if (sTop <= f2 - 100) { | if (sTop <= f2 - 100) { | ||
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fixRight.eq(2).addClass('cur').siblings().removeClass('cur'); | fixRight.eq(2).addClass('cur').siblings().removeClass('cur'); | ||
} | } | ||
| − | + | if (sTop >= f4 - 100) { | |
| + | fixRight.eq(3).addClass('cur').siblings().removeClass('cur'); | ||
| + | } | ||
} | } | ||
}) | }) | ||
Revision as of 21:55, 8 October 2018
sifA knock out
SifA maintains the integrity of Salmonella-containing vacuole (SCV) where Salmonella survive and replicate1. The exsistence of SCV limits GSDMD-N275 releasing to cytoplasma. what else, growth of ΔsifA mutant is inhibited in macrophage2.Thus, we knock out the sifA gene in order to prevent the stability of SCV and reduce the virulence of Salmonella. ΔsifA mutant was cnstructed by using gene editing systerm based on two-step allelic exchange3.
Targeting
Regulation of pyroptosis
Reference
