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<html lang="en"> | <html lang="en"> | ||
+ | <!--loader start--> | ||
+ | <style type="text/css"> | ||
+ | .chromeframe { | ||
+ | margin: 0.2em 0; | ||
+ | background: #ccc; | ||
+ | color: #000; | ||
+ | padding: 0.2em 0;} | ||
+ | #loader-wrapper { | ||
+ | position: fixed; | ||
+ | top: 0; | ||
+ | left: 0; | ||
+ | width: 100%; | ||
+ | height: 100%; | ||
+ | z-index:999999;} | ||
+ | #loader { | ||
+ | display: block; | ||
+ | position: relative; | ||
+ | left: 50%; | ||
+ | top: 50%; | ||
+ | width: 150px; | ||
+ | height: 150px; | ||
+ | margin: -75px 0 0 -75px; | ||
+ | border-radius: 50%; | ||
+ | border: 3px solid transparent; | ||
+ | /* COLOR 1 */ | ||
+ | border-top-color: #FFF; | ||
+ | -webkit-animation: spin 2s linear infinite; /* Chrome, Opera 15+, Safari 5+ */ | ||
+ | -ms-animation: spin 2s linear infinite; /* Chrome, Opera 15+, Safari 5+ */ | ||
+ | -moz-animation: spin 2s linear infinite; /* Chrome, Opera 15+, Safari 5+ */ | ||
+ | -o-animation: spin 2s linear infinite; /* Chrome, Opera 15+, Safari 5+ */ | ||
+ | animation: spin 2s linear infinite; /* Chrome, Firefox 16+, IE 10+, Opera */ | ||
+ | z-index:1001;} | ||
+ | #loader:before { | ||
+ | content: ""; | ||
+ | position: absolute; | ||
+ | top: 5px; | ||
+ | left: 5px; | ||
+ | right: 5px; | ||
+ | bottom: 5px; | ||
+ | border-radius: 50%; | ||
+ | border: 3px solid transparent; | ||
+ | /* COLOR 2 */ | ||
+ | border-top-color: #FFF; | ||
+ | -webkit-animation: spin 3s linear infinite; /* Chrome, Opera 15+, Safari 5+ */ | ||
+ | -moz-animation: spin 3s linear infinite; /* Chrome, Opera 15+, Safari 5+ */ | ||
+ | -o-animation: spin 3s linear infinite; /* Chrome, Opera 15+, Safari 5+ */ | ||
+ | -ms-animation: spin 3s linear infinite; /* Chrome, Opera 15+, Safari 5+ */ | ||
+ | animation: spin 3s linear infinite; /* Chrome, Firefox 16+, IE 10+, Opera */} | ||
+ | #loader:after { | ||
+ | content: ""; | ||
+ | position: absolute; | ||
+ | top: 15px; | ||
+ | left: 15px; | ||
+ | right: 15px; | ||
+ | bottom: 15px; | ||
+ | border-radius: 50%; | ||
+ | border: 3px solid transparent; | ||
+ | border-top-color: #FFF; | ||
+ | /* COLOR 3 */ | ||
+ | -moz-animation: spin 1.5s linear infinite; /* Chrome, Opera 15+, Safari 5+ */ | ||
+ | -o-animation: spin 1.5s linear infinite; /* Chrome, Opera 15+, Safari 5+ */ | ||
+ | -ms-animation: spin 1.5s linear infinite; /* Chrome, Opera 15+, Safari 5+ */ | ||
+ | -webkit-animation: spin 1.5s linear infinite; /* Chrome, Opera 15+, Safari 5+ */ | ||
+ | animation: spin 1.5s linear infinite; /* Chrome, Firefox 16+, IE 10+, Opera */} | ||
+ | |||
+ | |||
+ | @-webkit-keyframes spin { | ||
+ | 0%{ | ||
+ | -webkit-transform: rotate(0deg); /* Chrome, Opera 15+, Safari 3.1+ */ | ||
+ | -ms-transform: rotate(0deg); /* IE 9 */ | ||
+ | transform: rotate(0deg); /* Firefox 16+, IE 10+, Opera */ | ||
+ | }100%{ | ||
+ | -webkit-transform: rotate(360deg); /* Chrome, Opera 15+, Safari 3.1+ */ | ||
+ | -ms-transform: rotate(360deg); /* IE 9 */ | ||
+ | transform: rotate(360deg); /* Firefox 16+, IE 10+, Opera */} | ||
+ | } | ||
+ | |||
+ | @keyframes spin { | ||
+ | 0%{ | ||
+ | -webkit-transform: rotate(0deg); /* Chrome, Opera 15+, Safari 3.1+ */ | ||
+ | -ms-transform: rotate(0deg); /* IE 9 */ | ||
+ | transform: rotate(0deg); /* Firefox 16+, IE 10+, Opera */ | ||
+ | }100%{ | ||
+ | -webkit-transform: rotate(360deg); /* Chrome, Opera 15+, Safari 3.1+ */ | ||
+ | -ms-transform: rotate(360deg); /* IE 9 */ | ||
+ | transform: rotate(360deg); /* Firefox 16+, IE 10+, Opera */} | ||
+ | } | ||
+ | |||
+ | |||
+ | #loader-wrapper .loader-section { | ||
+ | position: fixed; | ||
+ | top: 0; | ||
+ | width: 51%; | ||
+ | height: 100%; | ||
+ | background: #197580; /* Old browsers */ | ||
+ | z-index: 1000; | ||
+ | -webkit-transform: translateX(0); /* Chrome, Opera 15+, Safari 3.1+ */ | ||
+ | -ms-transform: translateX(0); /* IE 9 */ | ||
+ | transform: translateX(0); /* Firefox 16+, IE 10+, Opera */} | ||
+ | #loader-wrapper .loader-section.section-left {left: 0;} | ||
+ | #loader-wrapper .loader-section.section-right {right: 0;} | ||
+ | |||
+ | /* Loaded */ | ||
+ | .loaded #loader-wrapper .loader-section.section-left { | ||
+ | -webkit-transform: translateX(-100%); /* Chrome, Opera 15+, Safari 3.1+ */ | ||
+ | -ms-transform: translateX(-100%); /* IE 9 */ | ||
+ | transform: translateX(-100%); /* Firefox 16+, IE 10+, Opera */ | ||
+ | -webkit-transition: all 0.7s 0.3s cubic-bezier(0.645, 0.045, 0.355, 1.000); | ||
+ | transition: all 0.7s 0.3s cubic-bezier(0.645, 0.045, 0.355, 1.000);} | ||
+ | .loaded #loader-wrapper .loader-section.section-right { | ||
+ | -webkit-transform: translateX(100%); /* Chrome, Opera 15+, Safari 3.1+ */ | ||
+ | -ms-transform: translateX(100%); /* IE 9 */ | ||
+ | transform: translateX(100%); /* Firefox 16+, IE 10+, Opera */ | ||
+ | -webkit-transition: all 0.7s 0.3s cubic-bezier(0.645, 0.045, 0.355, 1.000); | ||
+ | transition: all 0.7s 0.3s cubic-bezier(0.645, 0.045, 0.355, 1.000);} | ||
+ | .loaded #loader { | ||
+ | opacity: 0; | ||
+ | -webkit-transition: all 0.3s ease-out; | ||
+ | transition: all 0.3s ease-out;} | ||
+ | .loaded #loader-wrapper { | ||
+ | visibility: hidden; | ||
+ | -webkit-transform: translateY(-100%); /* Chrome, Opera 15+, Safari 3.1+ */ | ||
+ | -ms-transform: translateY(-100%); /* IE 9 */ | ||
+ | transform: translateY(-100%); /* Firefox 16+, IE 10+, Opera */ | ||
+ | -webkit-transition: all 0.3s 1s ease-out; | ||
+ | transition: all 0.3s 1s ease-out;} | ||
+ | /* JavaScript Turned Off */ | ||
+ | .no-js #loader-wrapper {display: none;} | ||
+ | .no-js h1 {color: #222222;} | ||
+ | #loader-wrapper .load_title { | ||
+ | font-family:'Open Sans'; | ||
+ | color:#FFF; font-size:19px; width:100%; text-align:center; z-index:9999999999999; position:absolute; top:60%; opacity:1; line-height:30px; } | ||
+ | #loader-wrapper .load_title span { font-weight:normal; font-style:italic; font-size:13px; color:#FFF; opacity:0.5;} | ||
+ | </style> | ||
+ | <script type="text/javascript"> | ||
+ | // | ||
+ | $(window).ready(function(){ | ||
+ | $('body').addClass('loaded'); | ||
+ | $('#loader-wrapper .load_title').remove(); | ||
+ | }); | ||
+ | </script> | ||
+ | |||
+ | <div id="loader-wrapper"> | ||
+ | <div id="loader"></div> | ||
+ | <div class="loader-section section-left"></div> | ||
+ | <div class="loader-section section-right"></div> | ||
+ | <div class="load_title">Now Loading...</div> | ||
+ | </div> | ||
+ | <!--loader end--> | ||
<link rel="stylesheet" type="text/css" href="https://2018.igem.org/Template:NJU-China/Erase_css?action=raw&ctype=text/css"> | <link rel="stylesheet" type="text/css" href="https://2018.igem.org/Template:NJU-China/Erase_css?action=raw&ctype=text/css"> | ||
<link rel="stylesheet" type="text/css" href="https://2018.igem.org/Template:NJU-China/Home_css?action=raw&ctype=text/css"> | <link rel="stylesheet" type="text/css" href="https://2018.igem.org/Template:NJU-China/Home_css?action=raw&ctype=text/css"> | ||
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}) | }) | ||
</script> | </script> | ||
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<div class="scrollbar" id="bar" style="width: 0%; background: orange;"></div> | <div class="scrollbar" id="bar" style="width: 0%; background: orange;"></div> | ||
<img id="mainimg" src="https://static.igem.org/mediawiki/2018/5/5a/T--NJU-China--teamlogo1.png" class="img1" alt="teamlogo"> | <img id="mainimg" src="https://static.igem.org/mediawiki/2018/5/5a/T--NJU-China--teamlogo1.png" class="img1" alt="teamlogo"> |
Revision as of 05:57, 23 June 2018
New Strategy for Treating
Fragile X Syndrome
by Targeting Expression of
FMRP Using TBEV5'-UTR
———— NJU-CHINA
Learn more about us!
We (NJU-China 2018 team) aim to find the possible therapy of the Fragile X Syndrome, a genetical disease causing a great number of ill of brain. As is previously analyzed, the syndrome is due to the reduction of a specific protein named FMR-1 in the dendrites of our neural cells. In order to innovate the treatment, we developed a strategy by using a designed sequence of mRNA to transfer the target gene specially into the dendrites for higher efficiency and accuracy. With the production of the certain sequence, we are able to maintain the production of certain protein in the neuron to the required level.