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− | <div class=" | + | <div class="header1" id="header-project"> Project </div> |
− | <div class=" | + | <div class="header2">Welcome to CO-RAD!</div> |
− | <div class=" | + | <div class="content"> |
+ | The complexity of genetic circuits has made it difficult for synthetic biologists to design the artificial | ||
+ | biological systems. In our project, we developed <span class="caption">CO-RAD</span>, a <span class="caption">Collaborative | ||
+ | Optimization</span> platform with multiple functions including <span class="caption">Recommendation, | ||
+ | Analysis and Design</span>. With the help of CO-RAD, users can design genetic circuits easily and cooperate | ||
+ | with remote partners <span class="caption">in real time</span>. | ||
+ | More importantly, the <span class="caption">search & recommendation system in CO-RAD</span> were developed to | ||
+ | inspire users with some previous projects and optimize their design <span class="caption">withevolutionary | ||
+ | algorithm</span>. Moreover, <span class="caption">a novel numerical simulation algorithm</span>(TODO:超链接:model-simulation | ||
+ | for circuit)applied in CO-RAD was developed to predict the expression level of genetic circuits in no time. | ||
+ | Through In addition, we incorporated self-designed <span class="caption">wet-lab validation</span>(TODO:超链接:Validation)into | ||
+ | our project to validate the new results designed by our CO-RAD platform. In conclusion, by assisting in | ||
+ | collaboration and inspiration, CO-RAD makes complex biological systems accessible to researchers who want | ||
+ | rapid, intuitive, and high-quality | ||
+ | accomplish their designs. | ||
+ | |||
+ | </div> | ||
+ | <div class="header2"> Description </div> | ||
<div class="content"> | <div class="content"> | ||
− | + | Groupwork is the bread and butter of biological system & circuit design, due to the complexity of this research | |
− | + | field. In consequence of the complexity of biological systems, genetic circuit design and the limited personal | |
− | + | experience, it is very difficult for individuals to design a viable circuit alone.This raises the demand of | |
− | + | effective collaboration methods. It would be better if the biologists can work face to face, in which way they | |
− | + | can exchange ideas with absolute ease. However, in many cases we can’t even make sure everyone works on the | |
− | + | same continent, let alone in the same room, so we need appropriate ways for tele-cooperation. Sadly, | |
− | + | traditional online tools don’t satisfy biologists’ needs. For example, genetic circuits and experimental | |
− | + | protocols cannot be precisely represented via Google Doc. Local designing software such as SBOLDesigner don’t | |
− | + | let scientists edit online cooperatively, which brings down efficiency a lot. Besides, creative ideas and | |
+ | valuable suggestions are also important in collaboration, which will have a great influence in the final result | ||
+ | of users’ co-design. | ||
</div> | </div> | ||
− | <img src=" | + | <img src="images/Pr-De-4.png" /> |
− | <div class="content"> we | + | <div class="content"> |
+ | Therefore, we're here to solve the following problems: | ||
+ | <br /> | ||
+ | (1) How to make tele-cooperation as convenient as face-to-face collaboration. | ||
+ | <br /> | ||
+ | (2) How to encourage users to think of and share more creative ideas while cooperating. | ||
</div> | </div> | ||
− | < | + | <div class="header2"> Solution </div> |
− | < | + | |
− | < | + | <div class="header3">Help users come up with more creative ideas</div> |
− | </ | + | <div class="ui three cards"> |
− | </ | + | <div class="card wide-card"> |
+ | <div class="image"> | ||
+ | <img src="https://static.igem.org/mediawiki/2018/6/63/T--SYSU-Software--Des4.png" /> | ||
+ | </div> | ||
+ | <div class="content"> | ||
+ | <div class="ui header">Search & recommendaion</div> | ||
+ | </div> | ||
+ | <div class="ui bottom attached button detail-btn" data-id="4">View Detail</div> | ||
+ | </div> | ||
+ | <div class="card wide-card"> | ||
+ | <div class="image"> | ||
+ | <img src="https://static.igem.org/mediawiki/2018/a/ae/T--SYSU-Software--Des5.png" /> | ||
+ | </div> | ||
+ | <div class="content"> | ||
+ | <div class="ui header">Analysis & simulation</div> | ||
+ | </div> | ||
+ | <div class="ui bottom attached button detail-btn" data-id="5">View Detail</div> | ||
+ | </div> | ||
+ | <div class="card wide-card"> | ||
+ | <div class="image"> | ||
+ | <img src="https://static.igem.org/mediawiki/2018/f/f3/T--SYSU-Software--Des6.png" /> | ||
+ | </div> | ||
+ | <div class="content"> | ||
+ | <div class="ui header">Guide the design</div> | ||
+ | </div> | ||
+ | <div class="ui bottom attached button detail-btn" data-id="6">View Detail</div> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="ui modal" id="modal-4"> | ||
+ | <div class="header">Search & recommendaion</div> | ||
+ | <div class="image content"> | ||
+ | <div class="ui medium image"> | ||
+ | <img src="https://static.igem.org/mediawiki/2018/6/63/T--SYSU-Software--Des4.png" /> | ||
+ | </div> | ||
+ | <div class="description"> | ||
+ | Given the experience of previous achievements provides valuable inspiration while cooperating, we | ||
+ | developed this function to help users quickly find the project they need. | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="actions"> | ||
+ | <div class="ui black deny button">Close</div> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="ui modal" id="modal-5"> | ||
+ | <div class="header">Analysis & simulation</div> | ||
+ | <div class="image content"> | ||
+ | <div class="ui medium image"> | ||
+ | <img src="https://static.igem.org/mediawiki/2018/a/ae/T--SYSU-Software--Des5.png" /> | ||
+ | </div> | ||
+ | <div class="description"> | ||
+ | Deeper understanding of the circuit design can help users make more hypothetical opinions. Our software | ||
+ | analyzes circuits and gives values for CG and CAI, and builds mathematical simulation models to predict | ||
+ | expression levels. | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="actions"> | ||
+ | <div class="ui black deny button">Close</div> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="ui modal" id="modal-6"> | ||
+ | <div class="header">Guide the design</div> | ||
+ | <div class="image content"> | ||
+ | <div class="ui medium image"> | ||
+ | <img src="https://static.igem.org/mediawiki/2018/f/f3/T--SYSU-Software--Des6.png" /> | ||
+ | </div> | ||
+ | <div class="description"> | ||
+ | Through an algorithm that simulates evolution, users can get optimal kinetic parameters for circuits, | ||
+ | which can assist users in modifying their circuits to reach the expected behavior. | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="actions"> | ||
+ | <div class="ui black deny button">Close</div> | ||
+ | </div> | ||
+ | </div> | ||
+ | |||
+ | <div class="header3">Solve the inconvenience of remote collaboration and communication</div> | ||
+ | <br /> | ||
+ | <div class="ui three cards"> | ||
+ | <div class="card wide-card"> | ||
+ | <div class="image"> | ||
+ | <img src="https://static.igem.org/mediawiki/2018/c/c9/T--SYSU-Software--Des1.png" /> | ||
+ | </div> | ||
+ | <div class="content"> | ||
+ | <div class="ui header">Real-time collaboration</div> | ||
+ | </div> | ||
+ | <div class="ui bottom attached button detail-btn" data-id="1">View Detail</div> | ||
+ | </div> | ||
+ | <div class="card wide-card"> | ||
+ | <div class="image"> | ||
+ | <img src="https://static.igem.org/mediawiki/2018/9/9a/T--SYSU-Software--Des2.png" /> | ||
+ | </div> | ||
+ | <div class="content"> | ||
+ | <div class="ui header">Synchroniaztion sketchpad</div> | ||
+ | </div> | ||
+ | <div class="ui bottom attached button detail-btn" data-id="2">View Detail</div> | ||
+ | </div> | ||
+ | <div class="card wide-card"> | ||
+ | <div class="image"> | ||
+ | <img src="https://static.igem.org/mediawiki/2018/b/b8/T--SYSU-Software--Des3.png" /> | ||
+ | </div> | ||
+ | <div class="content"> | ||
+ | <div class="ui header">SBOL support</div> | ||
+ | </div> | ||
+ | <div class="ui bottom attached button detail-btn" data-id="3">View Detail</div> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="ui modal" id="modal-1"> | ||
+ | <div class="header">Real-time collaboration</div> | ||
+ | <div class="image content"> | ||
+ | <div class="ui medium image"> | ||
+ | <img src="https://static.igem.org/mediawiki/2018/c/c9/T--SYSU-Software--Des1.png" /> | ||
+ | </div> | ||
+ | <div class="description"> | ||
+ | A real-time genetic circuit design platform where multiple users can edit one file at the same time, | ||
+ | just like (and even better than!) working on the same computer. | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="actions"> | ||
+ | <div class="ui black deny button">Close</div> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="ui modal" id="modal-2"> | ||
+ | <div class="header">Synchroniaztion sketchpad</div> | ||
+ | <div class="image content"> | ||
+ | <div class="ui medium image"> | ||
+ | <img src="https://static.igem.org/mediawiki/2018/9/9a/T--SYSU-Software--Des2.png" /> | ||
+ | </div> | ||
+ | <div class="description"> | ||
+ | A tool that simulates pen and paper, users can express their opinions by labeling or drawing during the | ||
+ | communication process. | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="actions"> | ||
+ | <div class="ui black deny button">Close</div> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="ui modal" id="modal-3"> | ||
+ | <div class="header">SBOL support</div> | ||
+ | <div class="image content"> | ||
+ | <div class="ui medium image"> | ||
+ | <img src="https://static.igem.org/mediawiki/2018/b/b8/T--SYSU-Software--Des3.png" /> | ||
+ | </div> | ||
+ | <div class="description"> | ||
+ | Our system is compatible with SBOL, the most common data format in the field of synthetic biology, | ||
+ | which means circuits edited on other software can be quickly imported into our software without | ||
+ | re-editing. | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="actions"> | ||
+ | <div class="ui black deny button">Close</div> | ||
+ | </div> | ||
+ | </div> | ||
+ | |||
+ | <div class="next-page-identify" data-value="3"></div> <!-- 这个是跳页标记 --> | ||
− | |||
− | |||
</div> | </div> | ||
+ | |||
+ | <script> | ||
+ | $('.detail-btn').on('click', function () { | ||
+ | $('#modal-' + $(this).attr('data-id')).modal('show'); | ||
+ | }); | ||
+ | </script> |
Revision as of 18:48, 15 October 2018
Project
Welcome to CO-RAD!
The complexity of genetic circuits has made it difficult for synthetic biologists to design the artificial biological systems. In our project, we developed, a platform with multiple functions including . With the help of CO-RAD, users can design genetic circuits easily and cooperate with remote partners . More importantly, the were developed to inspire users with some previous projects and optimize their design . Moreover, (TODO:超链接:model-simulation for circuit)applied in CO-RAD was developed to predict the expression level of genetic circuits in no time. Through In addition, we incorporated self-designed (TODO:超链接:Validation)into our project to validate the new results designed by our CO-RAD platform. In conclusion, by assisting in collaboration and inspiration, CO-RAD makes complex biological systems accessible to researchers who want rapid, intuitive, and high-quality accomplish their designs.
Description
Groupwork is the bread and butter of biological system & circuit design, due to the complexity of this research field. In consequence of the complexity of biological systems, genetic circuit design and the limited personal experience, it is very difficult for individuals to design a viable circuit alone.This raises the demand of effective collaboration methods. It would be better if the biologists can work face to face, in which way they can exchange ideas with absolute ease. However, in many cases we can’t even make sure everyone works on the same continent, let alone in the same room, so we need appropriate ways for tele-cooperation. Sadly, traditional online tools don’t satisfy biologists’ needs. For example, genetic circuits and experimental protocols cannot be precisely represented via Google Doc. Local designing software such as SBOLDesigner don’t let scientists edit online cooperatively, which brings down efficiency a lot. Besides, creative ideas and valuable suggestions are also important in collaboration, which will have a great influence in the final result of users’ co-design.
<img src="images/Pr-De-4.png" />
Therefore, we're here to solve the following problems:
(1) How to make tele-cooperation as convenient as face-to-face collaboration.
(2) How to encourage users to think of and share more creative ideas while cooperating.
Solution
Help users come up with more creative ideas
<img src="" />
Search & recommendaion
<img src="" />
Analysis & simulation
<img src="" />
Guide the design
Search & recommendaion
<img src="" />
Given the experience of previous achievements provides valuable inspiration while cooperating, we developed this function to help users quickly find the project they need.
Analysis & simulation
<img src="" />
Deeper understanding of the circuit design can help users make more hypothetical opinions. Our software analyzes circuits and gives values for CG and CAI, and builds mathematical simulation models to predict expression levels.
Guide the design
<img src="" />
Through an algorithm that simulates evolution, users can get optimal kinetic parameters for circuits, which can assist users in modifying their circuits to reach the expected behavior.
Solve the inconvenience of remote collaboration and communication
<img src="" />
Real-time collaboration
<img src="" />
Synchroniaztion sketchpad
<img src="" />
SBOL support
Real-time collaboration
<img src="" />
A real-time genetic circuit design platform where multiple users can edit one file at the same time, just like (and even better than!) working on the same computer.
Synchroniaztion sketchpad
<img src="" />
A tool that simulates pen and paper, users can express their opinions by labeling or drawing during the communication process.
SBOL support
<img src="" />
Our system is compatible with SBOL, the most common data format in the field of synthetic biology, which means circuits edited on other software can be quickly imported into our software without re-editing.
<script>
$('.detail-btn').on('click', function () { $('#modal-' + $(this).attr('data-id')).modal('show'); });
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