Difference between revisions of "Team:HUST-China/Modeling overview"

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Modeling overview

1. Overview

This year, our job can be mainly divided into three parts: model of system, sort of three genes pathway in Rhodopseudomonas, and intelligent device software.

2. Model of System

In order to see whether our system can work and how our system will work, we build a model to simulate our system. This model shows us the details of our system, inspire us how to improve our system and give our intelligent device software data so that we can change the application experiment to get a better result.

3. Sort of three genes

In Rhodopseudomonas, the sequence of genes in plasmid influences them expression ability. (Shou-Chen.2012) We have three genes to transfer. So we should find out which gene is the most important, and we sort three genes by their importance.

3. Intelligent device software

Using a new multi-culture bacteria system means that we should use a new fermentation strategy. So we use algorithm to know the situation of the system and decide how to control the device, so that the system will work more efficiently and steadily. Reference

Reference

[1] 2.Shou-Chen Lo. 2012. Enhancement of Hydrogen Production and Carbon Fixation in Purple Nonsulfur Bacterium by Synthetic Biology. Ph.D. Dissertation

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                    <h3><strong>1. <span class="red-content">Overview </span></strong></h3>
                    <p style="font-size:16px; line-height: 25px;letter-spacing:1px; text-indent:0px;">
-This year, our job can be mainly divided into three parts: Comparison of Rhodopseudomonas and Cyanobacteria, sort of three genes pathway in Rhodopseudomonas, and intelligent device software.
+This year, our job can be mainly divided into three parts: model of system, sort of three genes pathway in Rhodopseudomonas, and intelligent device software.
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-                   <h3><strong>2. <span class="red-content">Comparison between PSB</span></strong></h3>
+                   <h3><strong>2. <span class="red-content">Model of System</span></strong></h3>
                    <p style="font-size:16px; line-height: 25px;letter-spacing:1px; text-indent:0px;">
-In order to produce Lactate， we have two methods, using Cyanobacteria or Rhodopseudomonas. Cyanobacteria is used widely in the laboratory and has many papers to support.，Because it is more efficient and easier to control. But Shewanella is heterotrophic facultative anaerobes, and produces electricity only in anaerobic environment (Justin et al.2009). So we think Rhodopseudomonas may be better to act as an producer so the cycle photophosphorylation does not produce oxygen. But Rhodopseudomonas is not as efficient as Cyanobacteria. So we use computer simulation to find which one is better.
+In order to see whether our system can work and how our system will work, we build a model to simulate our system. This model shows us the details of our system, inspire us how to improve our system and give our intelligent device software data so that we can change the application experiment to get a better result.
 </p>
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              <h4><strong>Reference </strong></h4>
             <p style="font-size:16px; line-height: 25px;letter-spacing:1px; text-indent:0px;">
-<span>[1] Justin L. Burns, Thomas J. DiChristina. 2009. Anaerobic Respiration of Elemental Sulfur and Thiosulfate by Shewanella oneidensis MR-1 Requires psrA, a Homolog of the phsA Gene of Salmonella enterica Serovar Typhimurium LT2. American Society for Microbiology Journals</span></p>
+ <span>[1] 2.Shou-Chen Lo. 2012. Enhancement of Hydrogen Production and Carbon Fixation in Purple Nonsulfur Bacterium by Synthetic Biology. Ph.D. Dissertation</span></p>
-           <p style="font-size:16px; line-height: 25px;letter-spacing:1px; text-indent:0px;">
- <span>[2] 2.Shou-Chen Lo. 2012. Enhancement of Hydrogen Production and Carbon Fixation in Purple Nonsulfur Bacterium by Synthetic Biology. Ph.D. Dissertation</span></p>
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