Difference between revisions of "Team:Lund"

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<h1>Oxygen is the Issue</h1>
<p>The rapid development of biotechnology has allowed the utilization of microorganisms in the sustainable manufacturing of essential products used in our day to day lives. The demand for more energy efficient technologies is increasing as society places more emphasis on the environment. Our project revolves around the co-expression of a bacterial hemoglobin as a means to increase oxygen utilization which in turn improves the yields of these products.</p>
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<p>One of the most common bottlenecks in biomanufacturing are oxygen deprivations. Cells are often grown into high cell densities to optimize the products yields. This can in turn limit oxygen availability, resulting in slower growth and undesired fermentation products.</p>
 
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<h1>A Very Special<br> Hemoglobin</h1>
<p>The rapid development of biotechnology has allowed the utilization of microorganisms in the sustainable manufacturing of essential products used in our day to day lives. The demand for more energy efficient technologies is increasing as society places more emphasis on the environment. Our project revolves around the co-expression of a bacterial hemoglobin as a means to increase oxygen utilization which in turn improves the yields of these products.</p>
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<p>Vitreoscilla is a strictly aerobic organism which, during oxygen deprivations, expresses Vitreoscilla hemoglobin (VHb). This defense mechanism  allows the bacterium to survive in very hypoxic conditions. Its hemoglobin has been found to have very useful biotechnical applications in combating oxygen limitations.</p>
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<h1>Our Project</h1>
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<p>Our project investigates the protein productivity based on the degree of VHb expression. Low VHb expression will not do the job while too high starves the cell resources. The answer lays somewhere in between. Find out how (Link to design).</p>
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Revision as of 13:06, 17 October 2018

It all starts here

The rapid development of biotechnology has allowed the utilization of microorganisms in the sustainable manufacturing of essential products used in our day to day lives. The demand for more energy efficient technologies is increasing as society places more emphasis on the environment. Our project revolves around the co-expression of a bacterial hemoglobin as a means to increase oxygen utilization which in turn improves the yields of these products.

Oxygen is the Issue

One of the most common bottlenecks in biomanufacturing are oxygen deprivations. Cells are often grown into high cell densities to optimize the products yields. This can in turn limit oxygen availability, resulting in slower growth and undesired fermentation products.

A Very Special
Hemoglobin

Vitreoscilla is a strictly aerobic organism which, during oxygen deprivations, expresses Vitreoscilla hemoglobin (VHb). This defense mechanism allows the bacterium to survive in very hypoxic conditions. Its hemoglobin has been found to have very useful biotechnical applications in combating oxygen limitations.

Our Project

Our project investigates the protein productivity based on the degree of VHb expression. Low VHb expression will not do the job while too high starves the cell resources. The answer lays somewhere in between. Find out how (Link to design).

Modeling

Phasellus cursus lorem a posuere feugiat. Sed elementum mattis ligula dignissim pretium. Duis

Scaling up

Phasellus cursus lorem a posuere feugiat. Sed elementum mattis ligula dignissim pretium. Duis

Practices

Phasellus cursus lorem a posuere feugiat. Sed elementum mattis ligula dignissim pretium. Duis

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