Difference between revisions of "Team:SJTU-BioX-Shanghai/Story"
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| + | <p>In chapter 1, you will learn about how we brought up ECHO while from chapter 2 to chapter 4 we will introduce our four modules for you. In chapter 5, we will introduce our inspiring human practice. | ||
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| + | <br><br/> | ||
| + | <p>Now follow us to start the amazing trip. | ||
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| + | <div class="story_chapter_header"> | ||
| + | <h2>Chapter1</h2> | ||
| + | <img src="https://static.igem.org/mediawiki/2018/9/95/T--SJTU-BioX-Shanghai--content_nav_left.png"/> | ||
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| + | <div class="story_chapter_txt"> | ||
<p>On the first day of blazing June, which happened to be the International Children’s Day, ECHO was brought up by Kairan Zhang. But at that time, ECHO has only one part, the acoustic reporter gene (arg). We found it extremely interesting since nowadays researchers often use fluorescent proteins or beta-galactosidase as reporters. But what if we develop a brand new reporting system that involves unique characteristics? Is it possible that we can use this to conquer an existing problem? | <p>On the first day of blazing June, which happened to be the International Children’s Day, ECHO was brought up by Kairan Zhang. But at that time, ECHO has only one part, the acoustic reporter gene (arg). We found it extremely interesting since nowadays researchers often use fluorescent proteins or beta-galactosidase as reporters. But what if we develop a brand new reporting system that involves unique characteristics? Is it possible that we can use this to conquer an existing problem? | ||
</p> | </p> | ||
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<p>With this ultimate goal in mind, we go on brainstorming over and over again. And we came up with all these amazing ideas listed below. | <p>With this ultimate goal in mind, we go on brainstorming over and over again. And we came up with all these amazing ideas listed below. | ||
</p> | </p> | ||
| + | <!--*********************** list-elements template ***********************--> | ||
| + | <ul class="list-parallel-elements" > | ||
| + | <li>Detection of intestinal flora </li> | ||
| + | <li>Pharmacological research</li> | ||
| + | <li>Detection of metabolism</li> | ||
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| + | </ul> | ||
| + | <!--*********************** list-elements template ends ***********************--> | ||
<br><br/> | <br><br/> | ||
<p>However, none of these listed above really struck us. Until one day, we came across an article the author has used the args on imaging in vivo using ultrasound. We immediately realized that the most suitable application and the biggest advantage of args is imaging in vivo and this is exactly the key point of diagnosis in modern medicine. | <p>However, none of these listed above really struck us. Until one day, we came across an article the author has used the args on imaging in vivo using ultrasound. We immediately realized that the most suitable application and the biggest advantage of args is imaging in vivo and this is exactly the key point of diagnosis in modern medicine. | ||
</p> | </p> | ||
| − | + | ||
<p>After connecting args with ultrasound, we did tons of research about human diseases and at last we chose colon cancer as our target disease for the multiple reasons. First, colon cancer has a high morbidity both in China and the rest of the world and its existing diagnosis method, colonoscopy, has limited accessibility for public due to its painful process and great expense. If a cheap, convenient and noninvasive screening method is developed, and is affordable for most people, there is a great possibility that the morbidity of colon cancer can decrease greatly. | <p>After connecting args with ultrasound, we did tons of research about human diseases and at last we chose colon cancer as our target disease for the multiple reasons. First, colon cancer has a high morbidity both in China and the rest of the world and its existing diagnosis method, colonoscopy, has limited accessibility for public due to its painful process and great expense. If a cheap, convenient and noninvasive screening method is developed, and is affordable for most people, there is a great possibility that the morbidity of colon cancer can decrease greatly. | ||
</p> | </p> | ||
<p>Read more about background | <p>Read more about background | ||
</p> | </p> | ||
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<p>Since we have decided the core of our project, we moved on to designing our systems. In brief, our microbe incorporates four independent modules listed below. | <p>Since we have decided the core of our project, we moved on to designing our systems. In brief, our microbe incorporates four independent modules listed below. | ||
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<p>xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx </p> | <p>xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx </p> | ||
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Revision as of 18:56, 17 October 2018
Dear friends,
We are so glad to have you here. On this page, we will take you back to all the stories that happened this summer. You are going to see how ECHO grows from a simple idea to a complete project and eventually turns into reality. You can also find out how our team grows from 18 individuals to one collective.
In chapter 1, you will learn about how we brought up ECHO while from chapter 2 to chapter 4 we will introduce our four modules for you. In chapter 5, we will introduce our inspiring human practice.
Now follow us to start the amazing trip.
Chapter1
On the first day of blazing June, which happened to be the International Children’s Day, ECHO was brought up by Kairan Zhang. But at that time, ECHO has only one part, the acoustic reporter gene (arg). We found it extremely interesting since nowadays researchers often use fluorescent proteins or beta-galactosidase as reporters. But what if we develop a brand new reporting system that involves unique characteristics? Is it possible that we can use this to conquer an existing problem?
With this ultimate goal in mind, we go on brainstorming over and over again. And we came up with all these amazing ideas listed below.
- Detection of intestinal flora
- Pharmacological research
- Detection of metabolism
However, none of these listed above really struck us. Until one day, we came across an article the author has used the args on imaging in vivo using ultrasound. We immediately realized that the most suitable application and the biggest advantage of args is imaging in vivo and this is exactly the key point of diagnosis in modern medicine.
After connecting args with ultrasound, we did tons of research about human diseases and at last we chose colon cancer as our target disease for the multiple reasons. First, colon cancer has a high morbidity both in China and the rest of the world and its existing diagnosis method, colonoscopy, has limited accessibility for public due to its painful process and great expense. If a cheap, convenient and noninvasive screening method is developed, and is affordable for most people, there is a great possibility that the morbidity of colon cancer can decrease greatly.
Read more about background
Since we have decided the core of our project, we moved on to designing our systems. In brief, our microbe incorporates four independent modules listed below.
- CRC targeting module
- Ultrasonic Reporting module
- Suicide module
- Therapeutic module
With the combination of the four modules, we’ve constructed ECHO, a device that can target cancer cells, image the cancerous tissues using ultrasound and give a preliminary bio-treatment of CRC.
Read more about design.
xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx
Chapter2
xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx xxx
Chapter3
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Chapter4
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Chapter5
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Chapter6
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