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{{:Team:TU-Eindhoven/NavMenu}} | {{:Team:TU-Eindhoven/NavMenu}} | ||
<html> | <html> | ||
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<head> | <head> | ||
− | + | <style> | |
body, html { | body, html { | ||
height: 100%; | height: 100%; | ||
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} | } | ||
.bgimg-1 { | .bgimg-1 { | ||
− | background-image: url( | + | background-image: url(https://static.igem.org/mediawiki/2018/c/c9/T--TU-Eindhoven--BgImg1.jpeg); |
min-height: 500px; | min-height: 500px; | ||
} | } | ||
.bgimg-2 { | .bgimg-2 { | ||
− | background-image: url( | + | background-image: url(https://static.igem.org/mediawiki/2018/a/ad/T--TU-Eindhoven--homepageVideoThumbnail.jpeg); |
min-height: 400px; | min-height: 400px; | ||
} | } | ||
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.caption span.border { | .caption span.border { | ||
+ | line-height: 150%; | ||
background-color: #111; | background-color: #111; | ||
color: #fff; | color: #fff; | ||
padding: 18px; | padding: 18px; | ||
font-size: 25px; | font-size: 25px; | ||
− | letter-spacing: | + | letter-spacing: 3px; |
} | } | ||
h3 { | h3 { | ||
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text-transform: uppercase; | text-transform: uppercase; | ||
font: 20px "Lato", sans-serif; | font: 20px "Lato", sans-serif; | ||
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} | } | ||
#videoModal video { | #videoModal video { | ||
− | width: | + | width: 85%; |
margin:0 auto; | margin:0 auto; | ||
top: 50%; | top: 50%; | ||
left: 50%; | left: 50%; | ||
− | transform: translateX( | + | transform: translateX(9%) translateY(9%); |
} | } | ||
#videoModal { | #videoModal { | ||
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.closeFigure { | .closeFigure { | ||
position:fixed; | position:fixed; | ||
− | top: | + | top:25px; |
− | right: | + | right:45px; |
} | } | ||
+ | #tueMessage:hover { | ||
+ | background-color:rgba(255, 255, 255, 0.746); | ||
+ | } | ||
+ | #tueMessage { | ||
+ | cursor:default; | ||
+ | } | ||
+ | a:hover{ | ||
+ | text-decoration: none; | ||
+ | } | ||
+ | |||
</style> | </style> | ||
</head> | </head> | ||
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<div class="jumbotron neat"> | <div class="jumbotron neat"> | ||
<video id="bgvid" playsinline autoplay muted loop poster="https://static.igem.org/mediawiki/2018/a/ad/T--TU-Eindhoven--homepageVideoThumbnail.jpeg"> | <video id="bgvid" playsinline autoplay muted loop poster="https://static.igem.org/mediawiki/2018/a/ad/T--TU-Eindhoven--homepageVideoThumbnail.jpeg"> | ||
− | <source src="https://static.igem.org/mediawiki/2018/ | + | <source src="https://static.igem.org/mediawiki/2018/1/18/T--TU-Eindhoven--ShortVideoMuted.mp4" type="video/mp4"> |
</video> | </video> | ||
<!-- <div class="video-text"> | <!-- <div class="video-text"> | ||
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<div class="bgimg-1"> | <div class="bgimg-1"> | ||
<div class="caption"> | <div class="caption"> | ||
− | + | <span class="border">Welcome to GelCatraz: Where <em>E. coli</em> goes to stay!</span> | |
</div> | </div> | ||
</div> | </div> | ||
− | <div style="color: #777;background-color:white | + | <div style="color: #777;background-color:white;padding:50px 25%;text-align:justify;"> |
− | < | + | <p>Living biomaterials are an innovative type of device with wide-ranging implications. Combining the |
− | <p> | + | flexibility of living cells with biocompatiblematerials, this new class of devices is expected to |
− | + | impact many fields and assist society in dealing with the challenges ahead. Bacterial are a | |
− | + | particularly attractive platform since they can be genetically "tailored" to produce many different | |
− | + | types of proteins in response to almost any known type of chemical, physical or biological change. | |
− | + | </p> | |
− | + | <p> | |
− | + | Unfortunately, this potential is held back by challenges like maintaining the viability, functionality | |
− | + | and safety of the living components in freestanding materials and devices. One of the biggest | |
− | + | challenges in applying this emerging technology to real-world problems preventing bacterial leakage | |
− | + | while allowing for adequate diffusion of nutrients and products. In our project, we aimed to bring the | |
− | + | application of living materials a step closer to being realized. In the past several months we have | |
− | + | worked on our <a href="https://2018.igem.org/Team:TU-Eindhoven/Design">design</a> of a novel platform. Using an adhesive protein originating from arctic bacteria, | |
− | + | we <a href="https://2018.igem.org/Team:TU-Eindhoven/Results">successfully</a> reduced bacterial leakage by inducing genetically engineered <em>E. coli</em> to bind | |
− | + | to a dextran hydrogel with macroporous character. We used the modularity of our platform in a wound | |
+ | healing application, integrating in our design insights from our <a href="https://2018.igem.org/Team:TU-Eindhoven/Model">models</a> and <a href="https://2018.igem.org/Team:TU-Eindhoven/Human_Practices#stakeholder-container">feedback from stakeholders</a>. | ||
+ | We believe we have successfully completed all <a href="https://2018.igem.org/Team:TU-Eindhoven/Medal_Requirements">medal requirements</a> and have managed to <a href="https://2018.igem.org/Team:TU-Eindhoven/Results">demonstate</a> our | ||
+ | project in a prototype. | ||
+ | </p> | ||
</div> | </div> | ||
<div class="bgimg-2"> | <div class="bgimg-2"> | ||
<div class="caption"> | <div class="caption"> | ||
− | <span class="border" style="background-color: | + | <span id="tueMessage" class="border" style="background-color:rgba(255, 255, 255,0.5); font-size:25px;color: #312626;"> |
+ | Made with <span style="color:red">❤</span> from <span style="color:red">TU/e</span> | ||
+ | </span> | ||
</div> | </div> | ||
</div> | </div> | ||
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</div> | </div> | ||
</div> | </div> | ||
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<div id="videoModal" class="figureModalWindow"> | <div id="videoModal" class="figureModalWindow"> | ||
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</video> | </video> | ||
</div> | </div> | ||
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</html> | </html> | ||
{{:Team:TU-Eindhoven/footer}} | {{:Team:TU-Eindhoven/footer}} |
Latest revision as of 23:36, 17 October 2018
Living biomaterials are an innovative type of device with wide-ranging implications. Combining the flexibility of living cells with biocompatiblematerials, this new class of devices is expected to impact many fields and assist society in dealing with the challenges ahead. Bacterial are a particularly attractive platform since they can be genetically "tailored" to produce many different types of proteins in response to almost any known type of chemical, physical or biological change.
Unfortunately, this potential is held back by challenges like maintaining the viability, functionality and safety of the living components in freestanding materials and devices. One of the biggest challenges in applying this emerging technology to real-world problems preventing bacterial leakage while allowing for adequate diffusion of nutrients and products. In our project, we aimed to bring the application of living materials a step closer to being realized. In the past several months we have worked on our design of a novel platform. Using an adhesive protein originating from arctic bacteria, we successfully reduced bacterial leakage by inducing genetically engineered E. coli to bind to a dextran hydrogel with macroporous character. We used the modularity of our platform in a wound healing application, integrating in our design insights from our models and feedback from stakeholders. We believe we have successfully completed all medal requirements and have managed to demonstate our project in a prototype.