Difference between revisions of "Team:UIUC Illinois/Model"

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<h1> Modeling</h1>
 
<h1> Modeling</h1>
  
<p>Mathematical models and computer simulations provide a great way to describe the function and operation of BioBrick Parts and Devices. Synthetic Biology is an engineering discipline, and part of engineering is simulation and modeling to determine the behavior of your design before you build it. Designing and simulating can be iterated many times in a computer before moving to the lab. This award is for teams who build a model of their system and use it to inform system design or simulate expected behavior in conjunction with experiments in the wetlab.</p>
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<p>We constructed computational growth models of our S. cerevisiae/L. lactis co-culture
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based on monod kinetics. The monod equation is a simplified model for relating the growth
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rate of an organism to the concentration of a limiting substrate. We constructed out models
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based on the assumption that both organisms used glucose as their limiting substrate.
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These models informed what we expected to see in the lab.</p>
  
 
<img src = "https://static.igem.org/mediawiki/2018/9/93/T--UIUC_Illinois--Gro_sim.gif" height ="400" width="600"></img>
 
<img src = "https://static.igem.org/mediawiki/2018/9/93/T--UIUC_Illinois--Gro_sim.gif" height ="400" width="600"></img>

Revision as of 03:52, 18 October 2018

Modeling

We constructed computational growth models of our S. cerevisiae/L. lactis co-culture based on monod kinetics. The monod equation is a simplified model for relating the growth rate of an organism to the concentration of a limiting substrate. We constructed out models based on the assumption that both organisms used glucose as their limiting substrate. These models informed what we expected to see in the lab.

We utilized the Gro programming language to simulate the growth conditions of our co-culture.

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