Abstract
While building our model, we developed a software tool to help us find the optimal solution. After we finished, we modified the software and made it universal, which means it can be used by other researchers.
enzyme | Substrate | Turnover Number [1/s] | KM Value [mM] |
---|---|---|---|
ERG10 | acetyl-CoA | 2.1 | 0.33 |
ERG13 | acetoacetyl-CoA, acetyl-CoA | 4.6 | acetoacetyl-CoA:0.0014, acetyl-CoA:0.05 |
HMG1 | hydroxymethylglutaryl-CoA | 0.023 | 0.045 |
ERG12 | mevalonate | 2.36 | 0.012 |
ERG8 | phosphomevalonate | 3.4 | 0.0042 |
ERG19 | (R,S)-5-diphosphomevalonate | 5.9 | 0.0091 |
NDPS1 | isopentenyl diphosphate | 0.14 | 0.047 |