Team:NEU China A/Model

In the affected area of patients with inflammatory bowel disease, the concentration of nitric oxide is significantly increased, so we chose it as the input signal of our anti-inflammatory device. However, the nitric oxide is very unstable, so we have introduced an amplifier which can converts unstable gas signals into stable intracellular signals for sustained high-level output. The amplifier is based on a positive feedback loop. Transcription activator B-A can self-drive in a manner independent of the input signal for a period of time after the signal is input, and the metabolic flow in this cycle can be transferred to the output circuit (Figure 1).