Team:TecCEM

Enhance Tissue Regeneration.

In Mexico there is a great percentage of people that cannot afford the treatment of second degree burns. This type of injuries mentiones are the third cause of infant mortality in our country, this is an important issue that has to be solved.

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Abstract

In Mexico there is a great percentage of people that cannot afford the treatment of second degree burns. This type of injuries mentiones are the third cause of infant mortality in our country, this is an important issue that has to be solved. This project approaches that problem ith the design of a multi-glycopeptide scaffold and the recombinant growth factor Leptin B to induce fibroblast proliferation. Nanoencapsulation was employed to ensure proper delivery and distribution. Growth measurements were evaluated through cell image analysis and lactate dehydrogenase activity as an indirect indicator, obtained from the culture medium in the MiniSkin Simulator, which is a hardware to test molecules in a 3D culture. This system could enhance tissue regeneration, minimizing infection risks and treatment lapses for affected patients with second degree burns.

Why

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