Template:SYSU-Software/statics/html/Safety/DryLabSafety.html

Safety
Dry-lab Safety
Q:What about the biosafety matters to notice while using CO-RAD?
   A: As a responsible iGEM team, we need to consider about safety level of circuits designed in our collaboration
   platform. There are two major parts in iGEM we need to consider about. First is to choose a safe enough Chassis to
   redesign the circuits. Second, we need a safe enough Parts as material to make a Gene blueprint that benefits human
   beings. Therefore, this year, iGEM safety community announced <a href="https://2018.igem.org/Safety/White_List">2018
     White List</a>.
Q:What about the source of parts and its safety level in CO-RAD?
   A: The source information is stored in our database including the original chassis and the adapted chassis. The
   database has been screened manually.For safety in use, we only collected Parts belonged to Risk Group 1 &2, and
   prohibited Parts in Risk Group 3 & 4. For the rest parts, we divided them into three three safety level which is
   judged by two criteria:
  • 1 level: no "Red Flag" tag, belonging Chassis belongs to Risk Group 1.
  • 2 level: no "Red Flag" tag, belonging Chassis belongs to Risk Group 2.
  • 3 level: with "Red Flag" tag.
 <img src="T--SYSU-Software--safety.png" style="width: 50%">
Figure 1: Safety group distribution
Q:Are those Parts stored in the database of CO-RAD safe enough?
   A: iGEM safety community has already accessed a series of Parts with Biosafety danger, and the 'Red Flag' tag was
   set in Registry. BY manually screening all Parts in database, we found there were only few that are tagged with
   'Red Flag'. For safety in use, we will alert users whiling using these parts.

 <img src="T--SYSU-Software--Warning.png" style="width: 25%">
Figure 2: Warning of dangerous parts
Q:By cooperating with CO-RAD, will there be any potential dangerous operation?
A:
  1. We believe that collaboration is a good way to avoid potential danger. By adding a comment to the the circuit, users can send their partners warnings.
    2.        <img src="T--SYSU-Software--save_comment.png" />
    Figure 3: Comment on the design
  2. Meanwhile, to prevent users from adding dangerous chassis mistakely, chassis should be selected before collaboration begins. It allows other users to capture unexpected behaviours while cooperating.
    3.      <img src="T--SYSU-Software--chassis.png">
    Figure 4: Select chassis