Team:KUAS Korea/Description

Description

Medical and unit staffs are considered as the main route for secondary infection in the hospital since contacts between staffs and immunocompromised patients frequently occur in the confined space. Our plan is to develop a toolkit for detecting pathogens and further prevent the spread via staffs. We are trying to develop a toolkit that senses the presence and the quantity of pathogen such as MRSA. It is done by attaching fluorescent tags to the protein that specifically binds to the pathogen-specific surface protein. The proof of concept will be done by the detection of E.coli DH5-alpha, which is transformed to express the surface protein of the pathogen(e.g. MRSA). The development of such toolkit will resolve the problems regarding hospital-acquired infections (HAIs). HAIs may lead to complications and this can be potentially fatal to patients with compromised immune systems. For antibiotics are widely used and prescribed in hospitals, early detecting and eliminating antibiotic-resistance bacteria are crucial tasks for medical institutions. This method is cost-effective, multi-plexible, highly sensitive and specific to pathogens which enables easy and intuitive analysis.

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Inspiration

See how other teams have described and presented their projects:

• 2016 Imperial College
• 2016 Wageningen UR
• 2014 UC Davis
• 2014 SYSU Software

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References

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