Overview
We design a visualized liquid-crystal-based urine protein detector for early diagnosis of nephropathy. The antibody molecules are bound by antigens immobilized on the substrate of the liquid crystal cell, causing changes in the alignment of the liquid crystal molecules. After the polarized light passes, different brightness and color changes are produced depending on the amount of the immobilized antibody. This product uses the sensitive marker of diabetic nephropathy, beta2 microglobulin, as an antigen to ensure the detection of impaired renal function in the incipientDN. The detector is very simple to use. The user only needs to add one drop of urine to the detector and obtain visible results. Thus, our product is painless and household portable.
Our new application is to detect multiple proteins at the same time, and only need to add samples and antibody solutions to complete a simple visual inspection. We will develop a test kit for other diseases, the same principle is just to change to different markers and their antibodies. Therefore, our products have considerable application prospects.
