Team:RHIT/MetabolismModel




Metabolism Model



The FBA model allows us to run quick simulations on the growth of the E. coli on various environmental conditions [source]. Below is a specific simulation with just FBA, assuming the E. coli was growing in aerobic conditions on various carbon sources, all at the maximum flux of -10 mM/(gram of DW * hr).

Theoretical ATP Production of E.coli (1366 model) Growing on Different Media

The yield was predicted through maximizing the fluxes of reactions ATP synthase (with 4 protons per ATP) and both polyphosphate kinases.