description01
Can Cells be Controlled with Sound?
T oda y , it is r outine to induce the e xp r ession o f a gene in E . coli using only a small molecule . R e al small . T hink a r abinose , lactose , and rhamnose . P ouring th r ough p r evious r es e a r ch , we’ve determined th a t di r ected soundwaves can st r ess a cell ’ s pumps to open . La r ge enough for our ‘ e xp r ession inducing’ molecules to pass inside the cell‘s walls . One may ask , can sound become a r outine m e ans to induce gene e xp r ession in enginee r ed E . coli? While Sloveni a ’ s Sonicell and SUS T ech ’ s C e arll ’ s Sec r et p r ojects pursued a similar question in mammalian cells . We focused on inducing E. coli to express chromogenic reporters. . In other words , we’ve caused ta r geted cells to change colors by b e aming sound a t them . T oda y , it is r outine to induce the e xp r ession o f a gene in E . coli using only a small molecule . R e al small . T hink a r abinose , lactose , and rhamnose . P ouring th r ough p r evious r es e a r ch , we’ve determined th a t di r ected soundwaves can st r ess a cell ’ s pumps to open . La r ge enough for our ‘ e xp r ession inducing’ molecules to pass inside the cell‘s walls . One may ask , can sound become a r outine m e ans to induce gene e xp r ession in enginee r ed E . coli? While Sloveni a ’ s Sonicell and SUS T ech ’ s C e arll ’ s Sec r et p r ojects pursued a similar question in mammalian cells , we’ r e studying the details o f both p r ojects to induce ch r omogenesis in enginee r ed E. C oli cells . In English , we’ve caused ta r geted cells to change colors by b e aming sound a t them .
Description
Tell us about your project, describe what moves you and why this is something important for your team.
What should this page contain?
A clear and concise description of your project.
A detailed explanation of why your team chose to work on this particular project.
References and sources to document your research.
Use illustrations and other visual resources to explain your project.
Inspiration
See how other teams have described and presented their projects:
Advice on writing your Project Description
We encourage you to put up a lot of information and content on your wiki, but we also encourage you to include summaries as much as possible. If you think of the sections in your project description as the sections in a publication, you should try to be concise, accurate, and unambiguous in your achievements.
References
iGEM teams are encouraged to record references you use during the course of your research. They should be posted somewhere on your wiki so that judges and other visitors can see how you thought about your project and what works inspired you.
