Team:BIT/Practices/Silver

<!DOCTYPE html> Silver

Silver

In this section, we hope to present a panoramic view of the entire practice activity , so we list what we have done in chronological order and give a detailed description of each work. Every single work is carried out after careful arrangement and thinking.

WHEN: 5.9-6.3
WHERE: online
WHO: netizen
WHAT:
To know how other people thought about our JACOB2.0. We release a questionnaire online, and got 450 responses. It is really amazing that we received suggestions from people of different regions, different age groups even different education background . With their help, we made a conclusion which shaped our design and emphasis of the whole project .

WHEN: 6.8
WHERE: Aerospace General Hospital in Beijing
WHO: an expert in clinical laboratory department
WHAT:
We went to the hospital laboratory and asked the expert to verify the clinical application of biomarkers and the time consuming and cost of hospital detection.
We know that biomarkers are of great clinical significance, but hospitals do not have instruments for early disease screening.
The equipment of the hospital is more expensive, because turn on the machine to start one detection’s cost is high, so they will accumulate certain sample and then do the examination For the cost of the hospital surveillance project, by the price bureau and so on the department prescribes the price must be generally twice the cost.

WHEN: 8.2
WHERE: the remote areas of Guizhou province
WHO: the headmaster of the local primary school & the host of the local hotel
WHAT:
We conducted interviews about early disease screening and treatment of local people in remote areas of Guizhou province on the basis of summer education. After that, combined with online research, we have summed up three major causes of poverty due to illness: high time cost, high money cost, low medical resources.

WHEN: 8.15
WHERE: BOHUI-Tech in Beijing
WHO: the company's leading R & D staff
WHAT:
During our project this year, in order to investigate our chip and instrument design and marketing issues, we went to BOHUI-Tech. It is a special biological kit and microfluidic chip technology associated with manufacturing enterprises. We first had a visit around the company. The fully automated chip production really broaded our horizon.We even talked with the company's leading R & D staff about our overall design of the project and our questions. We received a lot of professional guidance.

WHEN: 8.25
WHERE: Liangxiang Campus of Beijing Institute of Technology
WHO: freshman and sophomore
WHAT:
We went to our university---Beijing Institute of Technology to do a preaching for the freshmen. They show a lot of curiosity about both iGEM and synthetic biology.
We patiently introduced iGEM to them and answered many questions they had about our team.

WHEN: 9.20/9.29
WHERE: High/middle school
WHO: students
WHAT:
We hope for children from the next generation of synthetic biology is the propaganda is not just a preach but long-term understanding and learning process, we used easy and understandable ways to introduce people to synthetic biology this year. We also design a mini program for students to learn and browsing about synthetic biology, iGEM, and related knowledge introduction together website recommendation. The enthusiasm of the students is so high that we get good feedback as below.
In fact, WeChat mini program is more than just a program. Our design for it is not only a simple introduction, but a platform for resource exchange and sharing. We will provide lab visits and iGEM training registration opportunities and simple basic knowledge testing in this program. It provides opportunities for high school students to study at a higher level. In the future, we would like to contact the high school affiliated to Beijing institute of technology, we also hope that we can realize the formalize synthetic biology lectures.

WHEN: 4.20-10.10
WHERE: Beijing Institute of Technology
WHO: Experts
WHAT:

Deng Yulin

Professor of Institute of space biomedical engineering
Professor deng yulin provided us with the overall idea of our project, especially on the implementation of the integrated chip and the overall feasibility of the project. He also shared us knowledge with in-depth explorations on the synthetic biology usage in detection and its significance. including suggestions on the construction and safety of the whole team.

Lv Xuefei

Associate professor of Institute of space biomedical engineering
She is an expert in research about biosensor. In the process of the project, Se has given us very important guidance on the function realization of the whole biosensor design.

Li Xiaoqiong

Associate professor of Institute of space biomedical engineering
He takes weak signal detection technology as the core research direction. As we hope in a new form for engineering bacterium fluorescence signal detection met difficult to reconcile the contradictions, but we asked him and seek for solution and with the help of him, we completed a a new type microbial sensor which takes smart phone as the core.

Xu Jiandong

Development department and public relation department manager of BO-HUI company
This summer, we went to BO-HUI company. we introduced our project to the technical staff of the development team and got many useful Suggestions. In addition, we also had a interview with Xu , and talk about marketing sections and the laws and regulations. Such as the need to show to the public unique and novel point but do not overturns the mainstream, and the need for relevant in vitro testing instrument and platform application and strictly comply with the required by laws and regulations, etc.

Li Yongrui , Li kunjie and Yang Yuanzhan. PhD and Graduate student

At the time of the device design, we had frets about how to make our device a more suitable place for biological experiment and the choice of device interface with the outside. Through interviews with them we got many suggestions and views, including the design of the interface need to be user friendly and easy to handle.Yang yuanzhan, graduate student, he can master skills in lab. He helped us to carry out a detailed analysis of the results and processes of biological experiments.


Fig 1.Experts help map for JACOB2.0

WHEN: 7.25-9.10
WHERE: Laws and regulations investigation
WHO: \
WHAT:
Laws & Regulations research can re-examine whether our projects conform to national regulations and requirements.
By carefully reading “Guiding principles for Registration and Application of quantitative Detection Reagents for tumor markers”, we learned about the product performance indicators that conform to the regulations. We checked the minimum detection limit, detection range, precision, specificity of our project and try to make the various indicators of our project to meet the requirements and optimize our project.
At the same time, we also want to know how to do if our biomarkers products can be put on the market, so we checked the "Registration Management method for in Vitro Diagnostic Reagents," and learn that the specific indicators should be determined according to the specific markers. And the product standard formulated by the applicant shall not be lower than the national standard or industry standard.

click practice1 and practice2 for regulations detail