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+ | SSTi-SZGD | ||
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+ | Tailor Of Time | ||
+ | </div> | ||
<div class="Hyaluronic"> | <div class="Hyaluronic"> | ||
Hyaluronic acid micro factory : A bacterium produces low molecular weight hyaluronic acid | Hyaluronic acid micro factory : A bacterium produces low molecular weight hyaluronic acid | ||
<!--{cn}透明质酸微工厂:一菌直接生产小分子透明质酸--> | <!--{cn}透明质酸微工厂:一菌直接生产小分子透明质酸--> | ||
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<!--{cn}通过微生物发酵产生的下透明质酸通常是通过--> | <!--{cn}通过微生物发酵产生的下透明质酸通常是通过--> | ||
<i>Streptococus species<!--{cn}兽疫链球菌--></i> | <i>Streptococus species<!--{cn}兽疫链球菌--></i> | ||
− | , which contains endotoxins. We constructed recombinant Bacillus subtilis, the food-grade safe species, to mass produce hyaluronic acid. | + | , which contains endotoxins. We constructed recombinant |
− | <!--{cn} | + | <!--{cn},但其中含有内毒素。为了安全的大量生产透明质酸,我们构建了食品级安全菌--> |
+ | <i>Bacillus subtilis<!--{cn}枯草芽孢杆菌--></i> | ||
+ | , the food-grade safe species, to mass produce hyaluronic acid. | ||
+ | <!--{cn}。--> | ||
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<div class="col-xs-12 col-md-6 img"></div> | <div class="col-xs-12 col-md-6 img"></div> | ||
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<div class="col-xs-12 col-md-6 img"></div> | <div class="col-xs-12 col-md-6 img"></div> | ||
<div class="col-xs-12 col-md-6 content"> | <div class="col-xs-12 col-md-6 content"> | ||
− | After covalently cross-link, low molecular weight hyaluronic acid (LMW-HA) forms stable hydrogel that is important for film-forming process. By introducing a hydrolase gene, we constructed a B. Subtilis strain that is able to biosynthesize LMW-HA. | + | After covalently cross-link, low molecular weight hyaluronic acid (LMW-HA) forms stable hydrogel that is important for film-forming process. By introducing a hydrolase gene, we constructed a |
− | <!--{cn} | + | <!--{cn}低分子量透明质酸(LMW-HA)共价交联后形成稳定的水凝胶,对成膜过程具有重要意义。通过引入水解酶基因,构建了一株能够生物合成LMW-HA的--> |
+ | <i>B. Subtilis<!--{cn}枯草芽孢杆菌--></i> | ||
+ | strain that is able to biosynthesize LMW-HA. | ||
+ | <!--{cn}菌株。--> | ||
</div> | </div> | ||
<div class="clearfix"></div> | <div class="clearfix"></div> | ||
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<!--paragraph 5--> | <!--paragraph 5--> | ||
<div class="col-xs-12 paragraph five" style="text-align: center;"> | <div class="col-xs-12 paragraph five" style="text-align: center;"> | ||
− | <div class="col-xs-12 img"></div> | + | <div class="col-xs-12 col-sm-6 img"></div> |
+ | <div class="col-xs-12 col-sm-6 img"></div> | ||
<div class="col-xs-12 content"> | <div class="col-xs-12 content"> | ||
We developed a novel cosmetic product: HA Micro-Needle Patch !!! | We developed a novel cosmetic product: HA Micro-Needle Patch !!! | ||
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</section> | </section> | ||
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</div> | </div> |
Revision as of 05:18, 13 October 2018
SSTi-SZGD
Tailor Of Time
Tailor Of Time
Hyaluronic acid micro factory : A bacterium produces low molecular weight hyaluronic acid
In our modern world, millions of people do not hesitate to spend a fortune to achieve younger looking and vibrant appearances, thus the cosmetic industry keeps growing.
Hyaluronic acid is one of the mostly used ingredients in cosmetic products, thanks to its exceptional water retention ability that helps rejuvenating skin and reducing wrinkles.
Hyaulornic acid production via microbial fermentation is generally through
Streptococus species
, which contains endotoxins. We constructed recombinant
Bacillus subtilis
, the food-grade safe species, to mass produce hyaluronic acid.
After covalently cross-link, low molecular weight hyaluronic acid (LMW-HA) forms stable hydrogel that is important for film-forming process. By introducing a hydrolase gene, we constructed a
B. Subtilis
strain that is able to biosynthesize LMW-HA.
We developed a novel cosmetic product: HA Micro-Needle Patch !!!
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- Application
- Applied Design
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- Demonstrate
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- Human Practices
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