Difference between revisions of "Team:DTU-Denmark/Model"

 
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<div class="headlinecontainer"><h1>Modeling</h1></div>
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<h3>★  ALERT! </h3>
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<p>This page is used by the judges to evaluate your team for the <a href="https://2018.igem.org/Judging/Medals">medal criterion</a> or <a href="https://2018.igem.org/Judging/Awards"> award listed below</a>. </p>
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<p> Delete this box in order to be evaluated for this medal criterion and/or award. See more information at <a href="https://2018.igem.org/Judging/Pages_for_Awards"> Instructions for Pages for awards</a>.</p>
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When $a \ne 0$, there are two solutions to \(ax^2 + bx + c = 0\) and they are
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$$x = {-b \pm \sqrt{b^2-4ac} \over 2a}.$$
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Modeling in the biological sciences provides a great tool for investigating and predicting outcomes based on a variety of different parameters. <br><br>
  
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From studying the fungal behavior in details to the structural behavior of the mycelium-based structures, we have been applying four different approaches to solve some of the problems and increase our understanding of the processes involved in the project. <br><br>
  
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The whole idea of basing structures on fungal mycelium relies on the growth and the optimization of the basic physical and mechanical properties of the fungus. We have therefore developed two different approaches to simulating the biomass growth; a detailed model following the location of <a href="https://2018.igem.org/Team:DTU-Denmark/GrowthModelling">hyphae and locations</a> and another one involving applying a system of partial differential equations (PDE) that models <a href="https://2018.igem.org/Team:DTU-Denmark/GrowthModelling">the biomass movement</a>.<br><br>
  
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When you change the characteristics of the mycelium, the structural properties will most likely also be influenced. The study of this has therefore been carried out by <a href="https://2018.igem.org/Team:DTU-Denmark/DesignOfExperiments">designing the building materials</a>, testing the designs and testing out whether the <a href="https://2018.igem.org/Team:DTU-Denmark/StructuralIntegrity">mycelium can withstand the pressure needed</a>.
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<h1> Modeling</h1>
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<p>Mathematical models and computer simulations provide a great way to describe the function and operation of BioBrick Parts and Devices. Synthetic Biology is an engineering discipline, and part of engineering is simulation and modeling to determine the behavior of your design before you build it. Designing and simulating can be iterated many times in a computer before moving to the lab. This award is for teams who build a model of their system and use it to inform system design or simulate expected behavior in conjunction with experiments in the wetlab.</p>
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<p style="text-align:center;"> <a href="https://2018.igem.org/Team:DTU-Denmark/GrowthModelling"><img class="hoverimg" src="https://static.igem.org/mediawiki/2018/8/8d/T--DTU-Denmark--model1-overview.jpg" style="max-width: 100%;" title="Growth Modeling"> </a>
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<p style="text-align:center;"> <a href="https://2018.igem.org/Team:DTU-Denmark/DesignOfExperiments"><img class="hoverimg" src="https://static.igem.org/mediawiki/2018/d/da/T--DTU-Denmark--model3-overview.jpg" style="max-width: 100%;" title="Design of Experiments"> </a>
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<p style="text-align:center;"> <a href="https://2018.igem.org/Team:DTU-Denmark/StructuralIntegrity"><img class="hoverimg" src="https://static.igem.org/mediawiki/2018/3/3d/T--DTU-Denmark--model2-overview.jpg" style="max-width: 100%;" title="Structural Integrity"> </a>
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<h3> Gold Medal Criterion #3</h3>
 
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Convince the judges that your project's design and/or implementation is based on insight you have gained from modeling. This could be either a new model you develop or the implementation of a model from a previous team. You must thoroughly document your model's contribution to your project on your team's wiki, including assumptions, relevant data, model results, and a clear explanation of your model that anyone can understand.
 
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The model should impact your project design in a meaningful way. Modeling may include, but is not limited to, deterministic, exploratory, molecular dynamic, and stochastic models. Teams may also explore the physical modeling of a single component within a system or utilize mathematical modeling for predicting function of a more complex device.
 
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Please see the <a href="https://2018.igem.org/Judging/Medals"> 2018
 
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Medals Page</a> for more information.
 
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<h3>Best Model Special Prize</h3>
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To compete for the <a href="https://2018.igem.org/Judging/Awards">Best Model prize</a>, please describe your work on this page  and also fill out the description on the <a href="https://2018.igem.org/Judging/Judging_Form">judging form</a>. Please note you can compete for both the gold medal criterion #3 and the best model prize with this page.  
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<h3> Inspiration </h3>
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                        <li><a style="font-size:16px;" href="mailto:dtubiobuilders@gmail.com">dtubiobuilders@gmail.com</a></li>
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Here are a few examples from previous teams:
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<li><a href="https://2016.igem.org/Team:Manchester/Model">2016 Manchester</a></li>
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<li><a href="https://2014.igem.org/Team:ETH_Zurich/modeling/overview">2014 ETH Zurich</a></li>
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Latest revision as of 01:56, 18 October 2018

Modeling

Modeling in the biological sciences provides a great tool for investigating and predicting outcomes based on a variety of different parameters.

From studying the fungal behavior in details to the structural behavior of the mycelium-based structures, we have been applying four different approaches to solve some of the problems and increase our understanding of the processes involved in the project.

The whole idea of basing structures on fungal mycelium relies on the growth and the optimization of the basic physical and mechanical properties of the fungus. We have therefore developed two different approaches to simulating the biomass growth; a detailed model following the location of hyphae and locations and another one involving applying a system of partial differential equations (PDE) that models the biomass movement.

When you change the characteristics of the mycelium, the structural properties will most likely also be influenced. The study of this has therefore been carried out by designing the building materials, testing the designs and testing out whether the mycelium can withstand the pressure needed.