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| <div class="mod-content modelo"> | | <div class="mod-content modelo"> |
| <h2><a name="model">Model</a></h2> | | <h2><a name="model">Model</a></h2> |
− | <p>Lorem ipsum dolor sit amet, consectetur adipiscing elit. Donec interdum lacinia posuere. Sed nunc felis, consequat a tincidunt eu, lacinia id nisi. Praesent eget erat consequat, ultrices justo nec, eleifend ex. Donec iaculis turpis id augue molestie, in venenatis enim pellentesque. Etiam quis semper diam, sit amet rhoncus libero. Vivamus pulvinar bibendum lacus, at iaculis enim tempor semper. In ac enim libero. Mauris at porta mi, in euismod arcu. | + | <p>With our project, we aimed to find a quantitative value for the crosstalk between quorum sensing systems. However, there is an intrinsic question about it: How to do it? How to look at the results of our measurements and find a relation between the systems? |
| </p> | | </p> |
− | <p>Lorem ipsum dolor sit amet, consectetur adipiscing elit. Donec interdum lacinia posuere. Sed nunc felis, consequat a tincidunt eu, lacinia id nisi. Praesent eget erat consequat, ultrices justo nec, eleifend ex. Donec iaculis turpis id augue molestie, in venenatis enim pellentesque. Etiam quis semper diam, sit amet rhoncus libero. Vivamus pulvinar bibendum lacus, at iaculis enim tempor semper. In ac enim libero. Mauris at porta mi, in euismod arcu. | + | <p>A natural way to adress this issue is to model the system. As a simplification of the world, modelling biological systems allows us to look only through the most interesting aspects we want to understand. So, with that in mind, we decided to construct a model where we can answer the core-question: How much interaction is there between the system complexes and their promoters? |
| </p> | | </p> |
− | <p>Lorem ipsum dolor sit amet, consectetur adipiscing elit. Donec interdum lacinia posuere. Sed nunc felis, consequat a tincidunt eu, lacinia id nisi. Praesent eget erat consequat, ultrices justo nec, eleifend ex. Donec iaculis turpis id augue molestie, in venenatis enim pellentesque. Etiam quis semper diam, sit amet rhoncus libero. Vivamus pulvinar bibendum lacus, at iaculis enim tempor semper. In ac enim libero. Mauris at porta mi, in euismod arcu. | + | <p>With this objective in mind and, using our design as foundation, with the goal to escalate to more complex ideas, our model aimed (and achieved) two basic objectives: |
| </p> | | </p> |
− | </div>
| + | <ul> |
− | </article>
| + | <li>Create a general model of quorum sensing systems, with which we can estimate the crosstalk between the systems and, therefore, be able to predict the behavior in future system studies (<a href="https://2018.igem.org/Team:USP-Brazil/Model">Single System Model and Predictions</a>)</li> |
− | | + | <li>Escalate the model to predict the behaviour in more complex combinations, from 2 to N systems in a single system, being able to determine the systems combinations with maximum orthogonality (<a href="https://2018.igem.org/Team:USP-Brazil/MultiModel">Multi-System Model</a>)</li> |
− | | + | </ul> |
− | <article>
| + | <p>We also proposed some <a href="https://2018.igem.org/Team:USP-Brazil/Statistics">stochastic and statistical analysis</a>, using some mathematical and computational approaches. |
− | <div class="mod-content simulacoes">
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− | <h2><a name="simu">Simulations</a></h2>
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− | <p>Lorem ipsum dolor sit amet, consectetur adipiscing elit. Donec interdum lacinia posuere. Sed nunc felis, consequat a tincidunt eu, lacinia id nisi. Praesent eget erat consequat, ultrices justo nec, eleifend ex. Donec iaculis turpis id augue molestie, in venenatis enim pellentesque. Etiam quis semper diam, sit amet rhoncus libero. Vivamus pulvinar bibendum lacus, at iaculis enim tempor semper. In ac enim libero. Mauris at porta mi, in euismod arcu. | + | |
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− | <p>Lorem ipsum dolor sit amet, consectetur adipiscing elit. Donec interdum lacinia posuere. Sed nunc felis, consequat a tincidunt eu, lacinia id nisi. Praesent eget erat consequat, ultrices justo nec, eleifend ex. Donec iaculis turpis id augue molestie, in venenatis enim pellentesque. Etiam quis semper diam, sit amet rhoncus libero. Vivamus pulvinar bibendum lacus, at iaculis enim tempor semper. In ac enim libero. Mauris at porta mi, in euismod arcu.
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− | <p>Lorem ipsum dolor sit amet, consectetur adipiscing elit. Donec interdum lacinia posuere. Sed nunc felis, consequat a tincidunt eu, lacinia id nisi. Praesent eget erat consequat, ultrices justo nec, eleifend ex. Donec iaculis turpis id augue molestie, in venenatis enim pellentesque. Etiam quis semper diam, sit amet rhoncus libero. Vivamus pulvinar bibendum lacus, at iaculis enim tempor semper. In ac enim libero. Mauris at porta mi, in euismod arcu.
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| </div> | | </div> |
| </article> | | </article> |
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− | <div class="mod-content etatistica">
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− | <h2><a name="stats">Statistics</a></h2>
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− | <p>Lorem ipsum dolor sit amet, consectetur adipiscing elit. Donec interdum lacinia posuere. Sed nunc felis, consequat a tincidunt eu, lacinia id nisi. Praesent eget erat consequat, ultrices justo nec, eleifend ex. Donec iaculis turpis id augue molestie, in venenatis enim pellentesque. Etiam quis semper diam, sit amet rhoncus libero. Vivamus pulvinar bibendum lacus, at iaculis enim tempor semper. In ac enim libero. Mauris at porta mi, in euismod arcu.
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− | <p>Lorem ipsum dolor sit amet, consectetur adipiscing elit. Donec interdum lacinia posuere. Sed nunc felis, consequat a tincidunt eu, lacinia id nisi. Praesent eget erat consequat, ultrices justo nec, eleifend ex. Donec iaculis turpis id augue molestie, in venenatis enim pellentesque. Etiam quis semper diam, sit amet rhoncus libero. Vivamus pulvinar bibendum lacus, at iaculis enim tempor semper. In ac enim libero. Mauris at porta mi, in euismod arcu.
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− | <p>Lorem ipsum dolor sit amet, consectetur adipiscing elit. Donec interdum lacinia posuere. Sed nunc felis, consequat a tincidunt eu, lacinia id nisi. Praesent eget erat consequat, ultrices justo nec, eleifend ex. Donec iaculis turpis id augue molestie, in venenatis enim pellentesque. Etiam quis semper diam, sit amet rhoncus libero. Vivamus pulvinar bibendum lacus, at iaculis enim tempor semper. In ac enim libero. Mauris at porta mi, in euismod arcu.
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| </main> | | </main> |
| </div> | | </div> |