Difference between revisions of "Team:Aix-Marseille"

 
(78 intermediate revisions by 5 users not shown)
Line 1: Line 1:
{{Aix-Marseille}}
+
{{Aix-Marseille/top|title=Home sweet home}}<html>
=Breaking Bugs - Project description=  
+
<link rel="stylesheet" href="https://2018.igem.org/wiki/index.php?title=Template:Aix-Marseille/flickity.css&action=raw&ctype=text/css">
 +
<script src="https://2018.igem.org/wiki/index.php?title=Template:Aix-Marseille/flickity.pkgd.min.js&action=raw&ctype=text/javascript"></script>
 +
<style>
 +
.igem_2018_team_content .igem_2018_team_column_wrapper { max-width: 90%; }
  
 +
.carousel-cell {
 +
  margin-right: 20%;
 +
  padding: 0 20%;
 +
  width: 100%;
 +
  display: flex;
 +
  align-items: center;
 +
  justify-content: center;
 +
  flex-wrap: wrap;
 +
}
 +
.carousel-cell .center-cell {
 +
  text-align: center;
 +
}
 +
.carousel-cell img { max-width: 100%; height: auto; }
 +
.carousel-cell .center-cell img { max-width: 40%; height: auto; }
 +
.carousel-cell div { max-width: 40em; }
  
Our focus this year is fighting bed bugs, a worldwide invasive pest, which is invading homes and biting humans for their blood. These tiny bugs became harmful to humans from the moment we made caves our homes, as the original hosts of bed bugs were bats.
 
Nowadays humans don’t live in caves, but this temporary troglodyte dwelling came with a cost: fighting against an insect addicted to human blood. While their bite usually don’t transmit any disease, it still induces serious dermatological and allergy issues.
 
  
Furthermore, only one bedbug is enough to declare a house good to be burnt to the ground ! To get rid of them, all personal effects must be decontaminated by fumigation or high temperature with the help of a professional. Thus, it requires people to leave their house for a few weeks. Moreover the fumigation has to be restarted a month later when eggs have hatched, because of their resistance to pesticides. This entire process comes with a very high cost !
+
/* no circle */
 +
.flickity-button {
 +
  background: transparent;
 +
}
 +
/* big previous & next buttons */
 +
.flickity-prev-next-button {
 +
  width: 50px;
 +
  height: 50px;
 +
}
 +
/* icon color */
 +
.flickity-button-icon {
 +
  fill: black;
 +
}
 +
/* hide disabled button */
 +
.flickity-button:disabled {
 +
  display: none;
 +
}
  
But have no fear, Aix-Marseille team is here. To find new ways to get rid of this pest we concentrated our efforts on three research axes. Firstly, the influence of pheromones on the sense of direction of beds bugs to create traps. Secondly, the possible use of chitinases and other proteases to break down the exoskeleton of the insect. Finally, disrupt the endosymbiotic bacterium of the bedbugs that allow the regulation of the reproduction to stop them from spreading.
+
/* position outside */
Together, we will find a solution to Break Bugs !
+
.flickity-prev-next-button.previous {
 +
  left: -20px;
 +
}
 +
.flickity-prev-next-button.next {
 +
  right: -20px;
 +
}
 +
 
 +
#sponsors ul, #sponsors li { margin: 0; padding: 0; }
 +
#sponsors ul { list-style: none; display: flex; align-items: center; overflow-x: auto; padding: 1em; justify-content: space-between;  }
 +
#sponsors li { margin-right: 1em; }
 +
#sponsors img { height: auto; max-height: 8em; width: 100%; }
 +
#bodyContent #sponsors a { background: none; background-image: none; }
 +
 
 +
</style>
 +
<script>
 +
 
 +
</script>
 +
</html>
 +
 
 +
<div class="main-carousel" data-flickity='{ "contain": true }'>
 +
<div class="carousel-cell" style="flex-direction: column">
 +
<p class="center-cell">
 +
[[File:T--Aix-Marseille--Bug_03.jpg]]
 +
</p>
 +
 
 +
<div style="text-align: center; text-transform: uppercase; font-weight: bold; font-family: sans-serif; font-size: 2.5em; line-height: 1.2em;">All bed bugs must come to an end !</div>
 +
</div>
 +
<div class="carousel-cell">
 +
<div style="padding: 2em">
 +
[[File:T--Aix-Marseille--wiki_3_2.jpg|300px]]
 +
</div>
 +
<div>
 +
== Project overview ==
 +
 
 +
Our focus this year is fighting '''bed bugs''', invasive pests distributed worldwide, that invade homes and bite humans for their blood. These tiny bugs became harmful from the moment humans made their homes in caves, as the original hosts of bed bugs were bats. Nowadays humans don’t live in caves, but this temporary troglodyte dwelling came with a cost: fighting against an insect addicted to human blood. While their bite usually doesn’t transmit any disease, it still induces serious dermatological and allergic problems.
 +
 
 +
We aim to find an efficient solution for eradicating bed bugs from infested living spaces.
 +
Our strategy consists of two integrated parts: using '''pheromones''' as a chemical lure that can attract bed bugs into a trap where they will be contaminated with '''''Beauveria bassiana''''', a virulent fungus for bed bugs, but safe for humans.
 +
 
 +
<div class="button_link" style="text-align:right"> [[Team:Aix-Marseille/Description|Learn more]]</div>
 +
</div>
 +
</div>
 +
<div class="carousel-cell"><div>
 +
 
 +
== Team ==
 +
[[File:T--Aix-Marseille--AMUT.png]]
 +
<div class="button_link" style="text-align:right"> [[Team:Aix-Marseille/Team|Meet the team]]</div>
 +
</div></div>
 +
<div class="carousel-cell">
 +
<div style="padding: 2em">
 +
[[File:T--Aix-Marseille--sciencebug.jpg|300px]]
 +
</div>
 +
<div>
 +
== Results ==
 +
Positive thoughts, positive actions and positive results.
 +
 
 +
As a hard working team, we aimed high this year. We have generated results that met with the bronze, silver and gold medals requirements. We were able to produce a functional endochitinase (Gold medal criterion), metabolic intermediates from the benzaldehyde/benzylalcohol biosynthesis pathway, and the DMTS/DMDS pheromones (Silver medal criterion) . We have successfully modelled the trap (Gold medal criterion) and tested it in infested premises.
 +
 
 +
Furthermore, we have made collaborations (Silver medal criterion) with the iGEM committee, as well as with private companies. This sets a solid ground for further developments around the project. Last but not least, a nationwide advertisement campaign engaged the public in our adventure. We had a mutual interest: all bed bugs must come to an end.
 +
 
 +
<div class="button_link" style="text-align:right"> [[Team:Aix-Marseille/Results|See our results]]</div>
 +
</div></div>
 +
 
 +
</div>
 +
 
 +
{{Aix-Marseille/Sponsors}}

Latest revision as of 02:59, 18 October 2018

Home sweet home

  • T--Aix-Marseille--logo-amu cmjn.eps.png
  • T--Aix-Marseille--FSDIE.png
  • T--Aix-Marseille--Amidex.png
  • T--Aix-Marseille--US.png