Difference between revisions of "Team:Aix-Marseille"

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{{Aix-Marseille/top|title=Breaking bugs}}
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{{Aix-Marseille/top|title=Home sweet home}}<html>
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= Project overview =
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Our focus this year is fighting bed bugs, a worldwide invasive pest, which is invading homes and biting humans for their blood. These tiny bugs became harmful to humans from the moment we made caves our homes, as the original hosts of bed bugs were bats. Nowadays humans don’t live in caves, but this temporary troglodyte dwelling came with a cost: fighting against an insect addicted to human blood. While their bite usually doesn’t transmit any disease, it still induces serious dermatological and allergy issues.
 
  
We aim to find an efficient solution for removing bedbugs from infested living spaces. Our strategy consists of two integrated parts: using pheromones as a chemical lure that can attract bedbugs to a trap where they will be eliminated using Beauveria bassiana, a highly virulent fungus to bedbugs, but safe for humans.
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The pheromones that we plan to use, are chemical molecules produced by the bugs themselves. They use them to navigate in space. Beauveria bassiana has a great ability to penetrate the protective layer of a bedbug (i.e. cuticle), leading consequently to the death of the insect by altering its circulatory system.
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[https://2018.igem.org/Team:Aix-Marseille/Description Learn more about the project ]
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[[File:T--Aix-Marseille--Bug_03.jpg]]
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<div style="text-align: center; text-transform: uppercase; font-weight: bold; font-family: sans-serif; font-size: 2.5em; line-height: 1.2em;">All bed bugs must come to an end !</div>
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== Project overview ==
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Our focus this year is fighting '''bed bugs''', invasive pests distributed worldwide, that invade homes and bite humans for their blood. These tiny bugs became harmful from the moment humans made their homes in caves, as the original hosts of bed bugs were bats. Nowadays humans don’t live in caves, but this temporary troglodyte dwelling came with a cost: fighting against an insect addicted to human blood. While their bite usually doesn’t transmit any disease, it still induces serious dermatological and allergic problems.
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We aim to find an efficient solution for eradicating bed bugs from infested living spaces.
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Our strategy consists of two integrated parts: using '''pheromones''' as a chemical lure that can attract bed bugs into a trap where they will be contaminated with '''''Beauveria bassiana''''', a virulent fungus for bed bugs, but safe for humans.
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<div class="button_link" style="text-align:right"> [[Team:Aix-Marseille/Description|Learn more]]</div>
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== Team ==
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[[File:T--Aix-Marseille--AMUT.png]]
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<div class="button_link" style="text-align:right"> [[Team:Aix-Marseille/Team|Meet the team]]</div>
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[[File:T--Aix-Marseille--sciencebug.jpg|300px]]
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== Results ==
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Positive thoughts, positive actions and positive results.
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As a hard working team, we aimed high this year. We have generated results that met with the bronze, silver and gold medals requirements. We were able to produce a functional endochitinase (Gold medal criterion), metabolic intermediates from the benzaldehyde/benzylalcohol biosynthesis pathway, and the DMTS/DMDS pheromones (Silver medal criterion) . We have successfully modelled the trap (Gold medal criterion) and tested it in infested premises.
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Furthermore, we have made collaborations (Silver medal criterion) with the iGEM committee, as well as with private companies. This sets a solid ground for further developments around the project. Last but not least, a nationwide advertisement campaign engaged the public in our adventure. We had a mutual interest: all bed bugs must come to an end.
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<div class="button_link" style="text-align:right"> [[Team:Aix-Marseille/Results|See our results]]</div>
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{{Aix-Marseille/Sponsors}}

Latest revision as of 02:59, 18 October 2018

Home sweet home

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